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Microfluidic chip having integrated electrodes

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-027/447
  • B32B-007/00
출원번호 US-0939327 (2001-08-24)
발명자 / 주소
  • Zhao, Mingqi
  • Vanysek, Petr
  • Ricco, Antonio
  • Lackritz, Hilary S.
  • Qun, Zhu
  • Nguyen, Uyen
  • Bjornson, Torleif O.
출원인 / 주소
  • Aclara Biosciences, Inc.
인용정보 피인용 횟수 : 200  인용 특허 : 64

초록

A microfluidic device having integrated components for conducting chemical operations. Depending upon the desired application, the components include electrodes for manipulating charged entities, heaters, electrochemical detectors, sensors for temperature, pH, fluid flow, and other useful components

대표청구항

1. A microfluidic device for operations at high field strengths comprising:a substrate having at least one channel and at least one aperture in fluid communication with said channel; a cover bonded to said substrate such that a reservoir is formed at said at least one aperture; and a driving electro

이 특허에 인용된 특허 (64)

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  127. Inman, Christina E.; Mastroianni, Alexander; Hinz, Wolfgang; Li, Shifeng; Benson, Scott C., Methods and systems for point of use removal of sacrificial material.
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  130. Bustillo, James; Schultz, Jonathan; Rearick, Todd; Milgrew, Mark, Methods for manufacturing high capacitance microwell structures of chemically-sensitive sensors.
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  132. Bustillo, James; Li, Shifeng, Methods for manufacturing well structures for low-noise chemical sensors.
  133. Levine, Peter, Methods for operating an array column integrator.
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  136. Rothberg, Jonathan; Hinz, Wolfgang; Johnson, Kim; Bustillo, James, Methods for operating chemically-sensitive sample and hold sensors.
  137. Trost, Peter Karl; Egan, Michael E.; South, Doug; Root, Brian E.; Scott, Orion N.; Landers, James P., Micro fluidic optic design.
  138. Kowalik, Daniel, Micro-fluidic bubble fuse.
  139. Prakash, Manu; Gershenfeld, Neil, Microfluidic bubble logic devices.
  140. Egan, Michael E.; Root, Brian; Scott, Orion N.; South, Douglas J.; Bienvenue, Joan M.; Kinnon, Paul; Landers, James; Saul, David; Tsuei, An-Chi; Hayes, Jason; Springer, Matthew; Solomon, Matthew; Van Ruijven, Peter, Microfluidic cartridge.
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  148. Ganesan, Karthik, Microfluidic devices having a reduced number of input and output connections.
  149. Ganesan, Karthik, Microfluidic devices having a reduced number of input and output connections.
  150. Handique, Kalyan; Brahmasandra, Sundaresh N.; Ganesan, Karthik; Williams, Jeff, Microfluidic system for amplifying and detecting polynucleotides in parallel.
  151. Handique, Kalyan; Brahmasandra, Sundaresh N; Ganesan, Karthik; Williams, Jeff, Microfluidic system for amplifying and detecting polynucleotides in parallel.
  152. Handique, Kalyan; Parunak, Gene; Haley, Cecelia, Microfluidic valve and method of making same.
  153. Handique, Kalyan; Parunak, Gene, Moving microdroplets in a microfluidic device.
  154. Handique, Kalyan; Parunak, Gene, Moving microdroplets in a microfluidic device.
  155. Bienvenue, Joan M; Landers, James P; Scott, Orion N, Multiple-sample microfluidic chip for DNA analysis.
  156. Fife, Keith, One-transistor pixel array.
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  162. Lau, Aldrich N. K., Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis.
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  170. Wu, Betty; Althaus, John S.; Brahmasandra, Sundaresh N.; Handique, Kalyan; Phadke, Nikhil, Processing polynucleotide-containing samples.
  171. Duffy, Patrick; Wilson, Kerry; Handique, Kalyan; Williams, Jeff, Rack for sample tubes and reagent holders.
  172. Duffy, Patrick; Wilson, Kerry; Handique, Kalyan; Williams, Jeff, Rack for sample tubes and reagent holders.
  173. Wilson, Kerry; Handique, Kalyan; Williams, Jeff; Brahmasandra, Sundaresh N., Reagent holder.
  174. Wilson, Kerry; Handique, Kalyan; Brahmasandra, Sundaresh N.; Williams, Jeff, Reagent holder, and kits containing same.
  175. Handique, Kalyan; Springer, Theodore, Reagent tube.
  176. Masters, Brett P.; Miller, Michael F., Resonant sensor systems and methods with reduced gas interference.
  177. Gubatayao, Thomas Catalino; Handique, Kalyan; Ganesan, Karthik; Drummond, Daniel M., Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection.
  178. Putnam, Jonathan; Li, Shifeng, Self-aligned well structures for low-noise chemical sensors.
  179. Jakoby, Bernhard, Sensor.
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  181. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Single piece reagent holder.
  182. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Single piece reagent holder.
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  184. Jordan, Jeremy; Rearick, Todd, System for reducing noise in a chemical sensor array.
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  189. Ganesan, Karthik; Handique, Kalyan, Systems and methods for thermal actuation of microfluidic devices.
  190. Ganesan, Karthik; Handique, Kalyan, Systems and methods for thermal actuation of microfluidic devices.
  191. Burns, Mark A.; Johnson, Brian N.; Chen, Michael, Thermal microvalves.
  192. Bustillo, James; Rearick, Todd; Hinz, Wolfgang; Fife, Keith, Titanium nitride as sensing layer for microwell structure.
  193. Fife, Keith G.; Johnson, Kim L.; Milgrew, Mark James, Two-transistor pixel array.
  194. Fife, Keith; Johnson, Kim; Milgrew, Mark, Two-transistor pixel array.
  195. Fife, Keith; Johnson, Kim; Milgrew, Mark, Two-transistor pixel array.
  196. Holm-Kennedy, James, Ultrasensitive biosensors.
  197. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Unitized reagent strip.
  198. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Unitized reagent strip.
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  200. Rearick, Todd; Milgrew, Mark James; Schultz, Jonathan; Papalias, Chris; Johnson, Kim L., Windowed sequencing.
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