Pharmaceutical agents containing acyclovir, fusaric acid and derivatives thereof
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-043/40
A01N-043/90
A01N-031/50
출원번호
US-0310614
(2002-12-03)
발명자
/ 주소
Douglas, Michael G.
Amin, Avinash N.
출원인 / 주소
Novactyl, Inc.
대리인 / 주소
Thompson Coburn LLP
인용정보
피인용 횟수 :
0인용 특허 :
2
초록▼
Compositions are provided, which comprise at least one nucleoside analogue inhibitor, pharmaceutically acceptable salts, solvates, or prodrugs thereof and fusaric acid, derivatives, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprising the above compositions are also p
Compositions are provided, which comprise at least one nucleoside analogue inhibitor, pharmaceutically acceptable salts, solvates, or prodrugs thereof and fusaric acid, derivatives, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprising the above compositions are also provided that optionally further include another therapeutically effective compound, such as a carrier. Systemic and topical preparations comprising the above compositions are also provided as well as methods of treating viral diseases by the administration of the above antiviral agents to a patient.
대표청구항▼
1. A method of treating a viral disease, disorder, or condition caused by a herpes simplex virus or varicella-zoster virus comprising topically administering to a patient afflicted with said disease, disorder, or condition a therapeutically effective dose of a pharmaceutically acceptable composition
1. A method of treating a viral disease, disorder, or condition caused by a herpes simplex virus or varicella-zoster virus comprising topically administering to a patient afflicted with said disease, disorder, or condition a therapeutically effective dose of a pharmaceutically acceptable composition comprising (1) about 1.75 μM acyclovir, a pharmaceutically acceptable salt, solvate or prodrug of acyclovir and (2) about 1 μg/m1 fusaric acid, or a pharmacologically acceptable salt of fusaric acid.2. A method of treating a viral disease, disorder, or condition caused by a herpes simplex virus or vancella-zoster virus comprising topically administering to a patient afflicted with said disease, disorder, or condition a therapeutically effective dose of a pharmaceutically acceptable composition comprising (1) about 1.75 μM acyclovir, a pharmaceutically acceptable salt, solvate or prodrug of acyclovir and (2) about 10 μg/m1 fusaric acid, or a pharmacologically acceptable salt of fusaric acid.3. A method of treating a viral disease, disorder, or condition caused by a herpes simplex virus or varicella-zoster virus comprising topically administering to a patient afflicted with said disease, disorder, or condition a therapeutically effective dose of a pharmaceutically acceptable composition comprising (1) about 6.1 μM acyclovir, a pharmaceutically acceptable salt, solvate or prodrug of acyclovir and (2) about 1 μg/m1 fusaric acid, or a pharmacologically acceptable salt of fusaric acid.4. A method of treating a viral disease, disorder, or condition caused by a herpes simplex virus or varicella-zoster virus comprising topically administering to a patient afflicted with said disease, disorder, or condition a therapeutically effective dose of a pharmaceutically acceptable composition comprising (1) about 6.1 μM acyclovir, a pharmaceutically acceptable salt, solvate or prodrug of acyclovir and (2) about 10 μg/m1 fusaric acid, or a pharmacologically acceptable salt of fusaric acid.
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이 특허에 인용된 특허 (2)
Fernandez-Pol Jose A., Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method.
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