IPC분류정보
국가/구분 |
United States(US) Patent
등록
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국제특허분류(IPC7판) |
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출원번호 |
US-0014933
(2001-10-22)
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발명자
/ 주소 |
- Hsu, William
- Smith, Joseph Martin
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출원인 / 주소 |
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대리인 / 주소 |
Schwegman, Lundberg, Woessner &
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인용정보 |
피인용 횟수 :
78 인용 특허 :
87 |
초록
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The present invention provides a system and a method for discriminating supraventricular tachyarrhythmias from ventricular arrhythmias during a tachycardia episode. First cardiac signals and second cardiac signals are sampled for cardiac complexes. A first feature on the first cardiac signal and a s
The present invention provides a system and a method for discriminating supraventricular tachyarrhythmias from ventricular arrhythmias during a tachycardia episode. First cardiac signals and second cardiac signals are sampled for cardiac complexes. A first feature on the first cardiac signal and a second feature on the second cardiac signal are utilized to determine an average time difference for a plurality of normal sinus rhythm complexes. A time difference between the first feature and the second feature is then determined for each cardiac complex of a tachycardiac rhythm. The cardiac complex is characterized as a ventricular tachycardia complex if the time difference exceeds the average time difference by a predetermined amount. Otherwise, it is classified as VT if its morphology after alignment is different from that during normal sinus rhythm.
대표청구항
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1. A method, comprising:sensing a first cardiac complex of a heart contraction at a first cardiac region of a patient; sensing a second cardiac complex, associated with the same heart contraction as the first cardiac complex, at a second cardiac region of said patient; selecting a first fiducial fea
1. A method, comprising:sensing a first cardiac complex of a heart contraction at a first cardiac region of a patient; sensing a second cardiac complex, associated with the same heart contraction as the first cardiac complex, at a second cardiac region of said patient; selecting a first fiducial feature of the first cardiac complex; selecting a second fiducial feature of the second cardiac complex; determining a time difference between the first and second fiducial features; comparing the time difference to a template time difference between the first and second fiducial features obtained from said patient during normal sinus rhythm; and if the time difference differs from the template time difference by at least a predetermined margin, characterizing the first and second signals as arrhythmic. 2. The method of claim 1, further including:if the time difference exceeds the template time difference by at least a predetermined margin, characterizing the heart contraction as a tachycardia heart contraction; determining a percentage of tachycardia heart contractions in a plurality of heart contractions; and when the percentage of tachycardia heart contractions exceeds a threshold, delivering therapy for treating the tachycardia. 3. The method of claim 1, wherein the first and second fiducial features include at least one of:a predetermined signal deviation from a baseline representing a beginning of the cardiac complex; a maximum deflection of the cardiac complex; a signal return to the baseline within a predetermined time window from the beginning of the cardiac complex, the signal return representing an end of the cardiac complex; and a maximum slope portion of the cardiac complex. 4. The method of claim 1, wherein the template time difference is obtained from said patient using the time differences determined for a plurality of heart contractions during normal sinus rhythm.5. A method, comprising:sensing a first cardiac complex at a first cardiac region during a cardiac cycle of a patient; sensing a second cardiac complex at a second cardiac region during the cardiac cycle; selecting a first fiducial feature of the first cardiac complex; selecting a second fiducial feature of the second cardiac complex; determining a first amplitude for the first fiducial feature relative to a baseline of the first cardiac complex; determining a second amplitude for the second fiducial feature relative a baseline of the second cardiac complex; comparing the first and second amplitudes to respective first and second thresholds obtained from said patient during normal sinus rhythm; and characterizing whether the first and second cardiac complexes are arrhythmic using the results of the comparison. 6. The method of claim 5, further comprising:determining the first threshold using a statistical value obtained from the first amplitudes over a plurality of cardiac cycles during normal sinus rhythm; and determining the second threshold using a statistical value obtained from the second amplitudes over a plurality of cardiac cycles during normal sinus rhythm. 7. The method of claim 5, wherein the characterizing includes:if the first amplitude differs from the first threshold by at least a predetermined amount, characterizing the cardiac complex as arrhythmic; and if the second amplitude differs from the second threshold by at least the predetermined amount, characterizing the cardiac complex as arrhythmic. 8. The method of claim 5, wherein the first and second fiducial features include at least one of:a predetermined signal deviation from a baseline representing a beginning of a cardiac complex; a maximum deflection of a cardiac complex; a signal return to the baseline within a predetermined time window from the beginning of a cardiac complex, the signal return representing an end of the cardiac complex; and a maximum slope portion of a cardiac complex. 9. A method, comprising:sensing a first cardiac complex at a first cardiac region of a patient during a cardiac cycle; sensing a second cardiac complex, associated with the same heart contraction as the first cardiac complex, at a second cardiac region during the cardiac cycle; determining a first slope of a portion of the first cardiac complex; determining a second slope of a portion of the second cardiac complex; comparing the first slope to a first threshold slope and comparing the second slope to a second threshold slope, the first and second threshold slopes obtained from said patient during normal sinus rhythm; and characterizing whether the first and the second signals are arrhythmic using the results of the comparison. 10. The method of claim 9, wherein the first slope is a maximum slope along the first cardiac complex during the cardiac cycle, and the second slope is the maximum slope along the second cardiac complex during the cardiac cycle.11. The method of claim 9, wherein the first slope is taken along a predetermined first major inflection of the first cardiac complex, and the second slope is taken at a substantially identical predetermined first major inflection of the second cardiac complex.12. The method of claim 9, further comprising:determining the first threshold slope over a plurality of cardiac cycles during normal sinus rhythm; and determining the second threshold slope over a plurality of cardiac cycles during normal sinus rhythm. 13. The method of claim 9, wherein the characterizing includes:if the first slope differs from the first threshold slope by at least a predetermined amount, characterizing the cardiac complex as arrhythmic; and if the second slope differs from the second threshold slope by at least the predetermined amount, characterizing the cardiac complex as arrhythmic. 14. A system, comprising:a control system including first and second inputs to monitor respective first and second signals, each including the same cardiac complex detected at different cardiac locations of a patient; a morphology analyzer coupled to the control system, the morphology analyzer adapted to locate a first fiducial feature of a first cardiac complex on the first signal and a second fiducial feature of a second cardiac complex on the second signal, the first and second fiducial features associated with the same heart contraction; a signal feature comparison circuit coupled to the morphology analyzer, the signal feature comparison circuit adapted to compare at least one characteristic of at least one of the first and second fiducial features to a template quantity obtained from said patient that is representative of a normal sinus rhythm complex; and wherein the control system designates the cardiac complex as arrhythmic when the at least one characteristic differs from the corresponding template time difference by at least a predetermined margin. 15. The system of claim 14, wherein the morphology analyzer includes a characteristic quantity generator, coupled to the signal feature comparison circuit, configured to generate at least one of:a time difference between the first and second fiducial features; a first amplitude of the first fiducial feature; a second amplitude of the second fiducial feature; a first slope associated with the first signal; and a second slope associated with the second signal. 16. The system of claim 15, further including a template generator, coupled to the signal feature comparison circuit, the template generator adapted to generate the template time differences over a plurality of cardiac complexes obtained from the patient during normal sinus rhythm.17. The system of claim 14, wherein the morphology analyzer includes an amplitude detector adapted to detect at least one of the first and second fiducial features, and wherein the at least one of the first and second fiducial features includes at least one of:a signal deviation from a baseline; a maximum signal deflection; a signal return to the baseline; and a predetermined major signal inflection. 18. The system of claim 17, wherein the morphology analyzer further includes a timer adapted to determine at least one time of detection of the at least one of the first and second fiducial features.
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