IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0435425
(2003-05-09)
|
발명자
/ 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
6 인용 특허 :
22 |
초록
▼
Apparatus and method for respiratory drug delivery using cartridge containing drug and propellant. User inserts cartridge into body of apparatus and activates piercing trigger to pierce drug compartment and propellant compartment, resulting in mixing and de-agglomeration of drug for respiratory deli
Apparatus and method for respiratory drug delivery using cartridge containing drug and propellant. User inserts cartridge into body of apparatus and activates piercing trigger to pierce drug compartment and propellant compartment, resulting in mixing and de-agglomeration of drug for respiratory delivery.
대표청구항
▼
1. A respiratory drug delivery system, comprising:a body;a piercing mechanism for piercing a drug compartment and a propellant compartment, the piercing mechanism comprising at least one pierce tubing, the pierce tubing comprising a lumen,wherein the lumen comprises a constriction for improved prope
1. A respiratory drug delivery system, comprising:a body;a piercing mechanism for piercing a drug compartment and a propellant compartment, the piercing mechanism comprising at least one pierce tubing, the pierce tubing comprising a lumen,wherein the lumen comprises a constriction for improved propellant velocity resulting in improved drug mixing or drug aerosolization; andwherein the drug compartment contains a drug, the propellant compartment contains a propellant, and piercing the drug compartment and the propellant compartment causes the propellant to flow into the drug compartment and aerosolize the drug for respiratory delivery through the body.2. The system of claim 1, further comprising a spacer for holding the aerosolized drug prior to respiratory delivery.3. A respiratory drug delivery system, comprising:a body;a piercing mechanism, for piercing a drug compartment and a propellant compartment;wherein the drug compartment comprises a first and a second drug sub-compartment, the first drug sub-compartment containing a first drug, the second sub-compartment containing a second drug, and wherein the propellant compartment comprises a first and a second propellant sub-compartment, the first propellant sub-compartment containing a first propellant, the second propellant sub-compartment containing a second propellant, and wherein the piercing mechanism comprises a first and a second pierce tubing, the first pierce tubing for piercing the first drug sub-compartment and the first propellant sub-compartment for aerosolizing the first drug, the second pierce tubing for piercing the second drug sub-compartment and the second propellant sub-compartment for aerosolizing the second drug.4. The system of claim 3, the first pierce tubing having shorter length than the second pierce tubing for staggered piercing of the drug sub-compartments and the propellant sub-compartments, resulting in staggered respiratory delivery of the first drug and the second drug.5. A cartridge apparatus, comprising:a first drug compartment containing a first drug;a second drug compartment containing a second drug;a first propellant compartment containing a first propellant for aerosolizing the first drug,a second propellant compartment containing a second propellant for aerosolizing the second drug, wherein the first drug compartment is joined to the first propellant compartment by a common membrane, the second drug compartment is joined to the second propellant compartment by a common membrane and the first drug and propellant compartments are fastened to the second drug and propellant compartments.6. A cartridge apparatus, comprising:a drug compartment containing a single dose of a drug; anda propellant compartment containing a propellant in a quantity suitable for aerosolizing the single dose of the drug,a propellant compartment containing a propellant for aerosolizing the drug; anda chaser compartment containing a chaser for providing secondary flow resulting in improved deposition of the drug, wherein the drug compartment is joined to the propellant compartment by a common membrane, and the propellant compartment is joined to the chaser compartment by a common membrane.7. A method for respiratory drug delivery, comprising:providing a cartridge according to claim 6,releasing the propellant from the propellant compartment;aerosolizing the drug using the released propellant;wherein the releasing step comprises piercing the propellant compartment; andreleasing a chaser from a chaser compartment for providing a secondary flow resulting in improved deposition of the drug.8. A method for respiratory drug delivery, comprising:providing a cartridge comprisinga drug compartment containing a single dose of a drug; anda propellant compartment containing a propellant in a quantity suitable for aerosolizing the single dose of the drug, wherein the drug compartment and propellant compartment are joined by a common membrane;releasing the propellant from the propellant compartment; andaerosolizing the drug using the released propellant;wherein the releasing step comprises piercing the propellant compartment.9. A cartridge comprising:a drug compartment containing a single dose of a drug;a propellant compartment containing a propellant in a quantity suitable for aerosolizing the single dose of the drug, wherein the drug compartment and propellant compartment are joined by a common membrane; anda plunger mechanism comprising a pierce head, the plunger mechanism being inside the propellant compartment;wherein movement of the plunger mechanism pierces the drug compartment and thrusts the propellant into the drug compartment, causing the propellant to aerosolize the drug for respiratory delivery.10. A cartridge comprising:a drug compartment containing a single dose of a drug;a propellant compartment containing a propellant in a quantity suitable for aerosolizing the single dose of the drug, wherein the drug compartment and propellant compartment are joined by a common membrane; anda plunger mechanism comprising a pierce head, the plunger mechanism being inside the propellant compartment;wherein movement of the plunger mechanism pressurizes the propellant, pierces the drug compartment and thrusts the propellant into the drug compartment, causing the propellant to aerosolize the drug for respiratory delivery.
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