국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0415856
(2002-08-08)
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우선권정보 |
DE-0042876 (2001-09-03) |
국제출원번호 |
PCT//DE02/02916
(2003-09-03)
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§371/§102 date |
20030903
(20030903)
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국제공개번호 |
WO03//026708
(2003-04-03)
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발명자
/ 주소 |
- Schunk, Werner
- Bruder, Michael
- Krause, Karl-Heinz
- Merkmann, Gerhard
- Vortkort, J?rg
|
출원인 / 주소 |
|
대리인 / 주소 |
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인용정보 |
피인용 횟수 :
37 인용 특허 :
10 |
초록
▼
A medical cushion (1), in particular an anti-decubitus cushion, is in particular multicellular and is distinguished in that the cushion is equipped, at least in the area where skin contact (6) occurs, with an active membrane (3) based on a skin-compatible matrix (4) into which a molecular sieve is m
A medical cushion (1), in particular an anti-decubitus cushion, is in particular multicellular and is distinguished in that the cushion is equipped, at least in the area where skin contact (6) occurs, with an active membrane (3) based on a skin-compatible matrix (4) into which a molecular sieve is mixed. This molecular sieve is charged with at least one active substance (Z, Z1, Z2), and the molecular sieve/active substance adduct (5) releases the active substance when the active membrane comes into skin contact (6) in conjunction with the transpiration of the skin.
대표청구항
▼
1. A medical cushion (1, 7), which is a multicellular anti-decubitus cushion, comprisinga cushion which is equipped, where skin contact (6, 13) occurs, with an active membrane (8, 9) based on a skin-compatible matrix (4, 10) into which a molecular sieve is mixed,said molecular sieve being charged wi
1. A medical cushion (1, 7), which is a multicellular anti-decubitus cushion, comprisinga cushion which is equipped, where skin contact (6, 13) occurs, with an active membrane (8, 9) based on a skin-compatible matrix (4, 10) into which a molecular sieve is mixed,said molecular sieve being charged with at least one active substance (Z, Z1, Z2, Z3, Z4), and a molecular sieve/active substance adduct (5, 11, 12) releases the active substance when the active membrane comes into skin contact (6, 13) in conjunction with the transpiration of the skin, andwherein the molecular sieve/active substance adduct (5, 11, 12) additionally contains crystallization water, such that the molecular sieve is partially dehydrated in relation to a sufficient base mol quantity (m) of crystallization water, andsaid molecular sieve containing the reduced mol quantity (m′) of crystallization water is charged with the active substance (Z, Z1, Z2, Z3, Z4) such that, when the active membrane (3, 9) comes into skin contact (6, 13), adsorption of water takes place during desoroption of the active substance and the crystallization water content of the molecular sieve increases.2. The medical cushion as claimed in claim 1,wherein the molecular sieve is a metal aluminum silicate of the following formula:Men[(AlO2)x·(SiO2)Y]; and a content of crystallization water selected from the group consisting of with crystallization water and without crystallization water.3. The medical cushion as claimed in claim 1,wherein the molecular sieve is a metal aluminum silicate of the following formula:Men[(AlO2)x·(SiO2)Y]·m(m′) H2O.4. The medical cushion as claimed in claim 2,wherein a metal of the first or second main group of the periodic table is used.5. The medical cushion as claimed in claim 4,wherein sodium is used as metal.6. The medical cushion as claimed in claim 2,wherein the molecular sieve is a sodium aluminum silicate of the following formula:Na86[(AlO2)86·(SiO2)106]; and with a content of crystallization water selected from the group consisting of with crystallization water and without crystallization water.7. The medical cushion as claimed in claim 3,wherein the molecular sieve is a sodium aluminum silicate of the following formula:Na86[(AlO2)86·(SiO2)106]·m(m′) H2O.8. The medical cushion as claimed in claim 1,wherein the molecular sieve contains a base mol quantity (m) of crystallization water of at least 100.9. The medical cushion as claimed in claim 7,wherein the molecular sieve is a sodium aluminum silicate of the following formula:Na86[(AlO2)86·(SiO2)106]·276 H2O.10. The medical cushion as claimed in claim 1,wherein the partially dehydrated molecular sieve has a degree of dehydration of at least 20%.11. The medical cushion as claimed in claim 1,wherein the degree of charging of the active substance (Z, Z1, Z2, Z3, Z4) in the molecular sieve/active substance adduct (5, 11, 12) is smaller than the degree of dehydration of the partially dehydrated molecular sieve.12. The medical cushion as claimed in claim 11,wherein the degree of charging is at least 50% of the degree of dehydration.13. The medical cushion as claimed in claim 1,wherein the molecular sieve/active substance adduct (5, 11, 12) is distributed substantially uniformly within the matrix (4, 10) of the active membrane (3, 9).14. The medical cushion as claimed in claim 1,wherein the molecular sieve/active substance adduct (5, 11, 12) has a proportion of 2 to 20% by weight, specifically relative to the total mass of the active membrane (3, 9).15. The medical cushion as claimed in claim 1,wherein the matrix (4, 10) of the active membrane (3, 9) is selected from the group consisting of a polymer, an elastomer, a thermoplastic elastomer and a thermoplastic.16. The medical cushion as claimed in claim 1,wherein the active membrane (3, 9) has a layer thickness of 0.5 mm to 2 mm.17. The medical cushion as claimed in claim 1,wherein with a uniform degree of dehydration, the molecular sieve is charged with at least a first active substance (Z1) and a second active substance (Z2) which are distinguished by a different degree of charging,so that the molecular sieve/active substance adduct (5) releases the active substances (Z1, Z2) sequentially when the active membrane (3) makes skin contact (6).18. The medical cushion as claimed in claim 1,wherein at least a first molecular sieve and a second molecular sieve are mixed into the matrix (10), which molecular sieves are of the same type but are distinguished by a different degree of dehydration, the first molecular sieve being charged with a first active substance (Z3) and the second molecular sieve being charged with a second active substance (Z4), and specifically with an approximately identical degree of charging,so that a first molecular sieve/active substance adduct (11) and a second molecular sieve/active substance adduct (12) release the active substances (Z3, Z4) sequentially when the active membrane (9) makes skin contact (13).19. The medical cushion as claimed in claim 1,wherein the active membrane (3, 9) is exchangeable.20. A method for producing a medical cushion (1, 7) comprising the following method steps:charging a molecular sieve with at least one active substance (Z, Z1, Z2, Z3, Z4) to form a molecular sieve/active substance adduct (5, 11, 12); and carrying out the charging at normal pressure;mixing the molecular sieve/active substance adduct (5, 11, 12) into the matrix (4, 10) to form the active membrane (3, 9); andfinally, assembling the active membrane (3, 9) with the medical cushion (1, 7).21. The method as claimed in claim 20, comprisingcarrying out the charging using a mortar mill or ball mill.22. The method as claimed in claim 20, comprisingcarrying out the charging in the presence of an inert gas.23. The method as claimed in claim 20, comprising the following method steps:partially dehydrating the molecular sieve with a sufficient base mol quantity (m) of crystallization water at 100 to 500° C., for several hours;charging the partially dehydrated molecular sieve with the reduced mol quantity (m′) of crystallization water with at least one active substance (Z, Z1, Z2, Z3, Z4) to form the molecular sieve/active substance adduct (5, 11, 12);mixing the molecular sieve/active substance adduct (5, 11, 12) into the matrix (4, 10) to form the active membrane (3, 9); andfinally, assembling the active membrane (3, 9) with the medical cushion (1, 7).24. The method as claimed in claim 23, comprisingcarrying out the dehydration at normal pressure.25. The method as claimed in claim 23, comprisingcarrying out the dehydration in the presence of an inert gas.26. The medical cushion as claimed in claim 8,wherein the molecular sieve contains a base mol quantity (m) of crystallization water of at least 200.27. The medical cushion as claimed in claim 10,wherein the partially dehydrated molecular sieve has a degree of dehydration of 40% to 70%.28. The medical cushion as claimed in claim 14,wherein the molecular sieve/active substance adduct (5, 11, 12) has a proportion of 5 to 10% by weight, specifically relative to the total mass of the active membrane (3, 9).29. The medical cushion as claimed in claim 16,wherein the active membrane (3, 9) has a layer of thickness of 1 mm.30. The method as claimed in claim 22, comprisingcarrying out the charging in the presence of nitrogen.31. The method as claimed in claim 23, comprising the following method steps:partially dehydrating the molecular sieve with a sufficient base mol quantity (m) of crystallization water at 350 to 450° C., for 2 to 6 hours;charging the partially dehydrated molecular sieve with the reduced mol quantity (m′) of crystallization water with at least one active substance (Z, Z1, Z2, Z3, Z4) to form the molecular sieve/active substance adduct (5, 11,12);mixing the molecular sieve/active substance adduct (5, 11, 12) into the matrix (4, 10) to form the active membrane (3, 9); andfinally assembling the active membrane (3, 9) with the medical cushion (1, 7).32. The method as claimed in claim 25, comprisingcarrying out the dehydration in the presence of nitrogen.
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