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Reversible geling co-polymer and method of making 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
출원번호 US-0209541 (1998-12-11)
발명자 / 주소
  • Gutowska, Anna
출원인 / 주소
  • Battelle Memorial Institute
대리인 / 주소
    Klarquist Sparkman, LLP
인용정보 피인용 횟수 : 21  인용 특허 : 51

초록 ▼

The present invention is a thereapeutic agent carrier having a thermally reversible gel or geling copolymer that is a linear random copolymer of an [meth-]acrylamide derivative and a hydrophilic comonomer, wherein the linear random copolymer is in the form of a plurality of linear chains having a pl

대표청구항 ▼

1. A biodegradable thermally reversibIe graft copolymer, comprising:a. a biodegradable, resorbable polymer; grafted with b. a side chain selected from the group consisting of homo-oligomers of[meth-]acrylamide derivatives and co-oligomers of [meth-]acrylamide derivatives copolymerized with hydrophil

이 특허에 인용된 특허 (51)

  1. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
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  10. Takahashi Toru (Shizuoka-ken JPX) Nakamura Hideki (Kanagawa-ken JPX) Goto Katsuya (Fukuoka-ken JPX), High polymer gel and vascular lesion embolizing material comprising the same.
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  11. Weissleder Ralph (Charlestown MA) Bogdanov Alexei (Newton MA), Hydrogel compositions and methods of use.
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  13. Bae You H. (Salt Lake City UT) Kim Sun W. (Salt Lake City UT), Implantable and refillable biohybrid artificial pancreas.
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  16. Tanaka Toyoichi (Wellesley MA) Ilmain Franck (St. Etienne FRX) Kokufuta Etsuo (Tsukuba JPX) Annaka Masahiko (Arlington MA), Interpenetrating-polymer network phase-transition gels.
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  17. Slepian Marvin ; Massia Stephen P., Local polymeric gel cellular therapy.
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  19. Slepian Marvin (Tucson AZ) Massia Stephen P. (Tucson AZ), Local polymeric gel therapy.
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  20. Levy, Richard, Lubricant compositions and methods.
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  21. Ito Shoji (Tsukuba JPX) Matsumaru Yuji (Tsukuba JPX) Hirano Takashi (Tsukuba JPX) Ohashi Shinichi (Tsukuba JPX), Method for vascular embolization.
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  22. Fernandez Julio M. ; Knudson Mark B., Method of delivering a lipid-coated condensed-phase microparticle composition.
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  23. Leavitt Richard D. ; Avila Luis Z., Method of local radiotherapy by polymerizing a material in vivo to form a hydrogel.
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  24. Hubbell Jeffrey A. (Austin TX) Elbert Donald (Austin TX) Hill-West Jennifer L. (Austin TX) Drumheller Paul D. (Austin TX) Chowdhury Sanghamitra (Round Rock TX) Sawhney Amarpreet (Newton MA), Multifunctional organic polymers.
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  25. Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
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  26. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill-West Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
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  27. Yokoyama Masayuki (Matsudo JPX) Sakurai Yasuhisa (Tokyo JPX) Okano Teruo (Ichikawa JPX) Kataoka Kazunori (Kashiwa JPX), Physical trapping type polymeric micelle drug preparation.
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  28. Wu Chi,HKX ; Jiang Suhong,HKX, Polymer gel composition and uses therefor.
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  29. Beth L. Armstrong ; Allison A. Campbell ; Anna Gutowska ; Lin Song, Polymer/ceramic composites.
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  30. Richard D. Leavitt ; Luis Z. Avila, Polymeric delivery of radionuclides and radiopharmaceuticals.
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  31. Slepian Marvin J. (Tucson AZ), Polymeric endoluminal paving process.
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  32. Schober Barton J. ; Pialet Joseph W. ; Pollack Robert A. ; Clark Denise R., Polymeric materials to self-regulate the level of polar activators in electrorheological fluids.
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  34. Mori Yuichi (Kanagawa JPX) Sakai Toshiya (Kanagawa JPX), Polymeric temperature sensitive drug carrier.
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  36. Coombes Allan G. A. (San Antonio TX) Heckman James D. (San Antonio TX) Boyan Barbara D. (San Antonio TX), Process of making a resorbable implantation device.
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  37. Bae You H. (Salt Lake City UT) Kim Sung W. (Salt Lake City UT) Valuev Lev I. (Moscow SUX), Pulsatile drug delivery device using stimuli sensitive hydrogel.
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  38. Greff Richard J. ; Wallace George, Radioactive embolizing compositions.
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  39. Bromberg Lev ; Lupton Elmer Cornelius (E.C.) ; Schiller Matthew E. ; Timm Mary Jo (M.J.) ; McKinney George, Responsive polymer networks and methods of their use.
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  40. Joshi Abhay (Irvine CA) Ding Shulin (Irvine CA) Himmelstein Kenneth J. (Irvine CA), Reversible gelation compositions and methods of use.
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  41. Hoeg Anne L. (Havnegaten CA NOX) Meadows David L. (Mission Viejo CA), Reversible gelation emulsion compositions and methods of use.
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  42. Tanaka Toyoichi (Newton MA) Hirokawa Yoshitsugu (Winchester MA), Reversible, discontinuous volume changes of ionized isopropylacrylamide cells.
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  45. Li Yong ; Hu Zhibing ; Zhang Xiaomin, Synthesis and use of heterogeneous polymer gels.
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  46. Mumick Pavneet Singh ; Chang Yihua ; Wang James Hongxue, Temperature sensitive polymers and water-dispersible products containing the polymers.
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  47. Gould Francis E. (Princeton) Johnston Christian W. (Neshanic Station) Seems George E. (Pennington NJ), Thermally reversible polyurethane hydrogels and cosmetic, biological and medical uses.
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  49. Cha Younsik (Salt Lake City UT) Choi Young Kweon (Salt Lake City UT) Bae You Han (Kwangju KRX), Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers.
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  50. Bae You H. (Salt Lake City UT), pH and temperature sensitive terpolymers for oral drug delivery.
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  51. Chang Nienyuan J. (Irvine CA), pH sensitive, reversible gelling, copolymeric erodible drug delivery system.
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  3. Amoroso, Nicholas J.; Badylak, Stephen Francis; Hong, Yi; Huber, Alexander; Takanari, Keisuke; Wagner, William R., Biohybrid composite scaffold.
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  4. Fuller, Gerald G.; Rappleye, C. Travis; Mandrusov, Evgenia, Compositions and methods for joining non-conjoined lumens.
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  7. Duerig, Urs T.; Frommer, Jane Elizabeth; Gotsmann, Bernd Walter; Hagberg, Erik Christopher; Hedrick, James Lupton; Knoll, Armin W.; Lee, Victor Yee-Way; Magbitang, Teddie Peregrino; Miller, Robert Dennis; Pratt, Russell Clayton; Wade, Charles Gordon; Windeln, Johannes, Method for high density data storage and imaging.
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  8. Duerig, Urs T.; Frommer, Jane Elizabeth; Gotsmann, Bernd Walter; Hagberg, Erik Christopher; Hedrick, James Lupton; Knoll, Armin W.; Lee, Victor Yee-Way; Magbitang, Teddie Peregrino; Miller, Robert Dennis; Pratt, Russell Clayton; Wade, Charles Gordon; Windeln, Johannes, Method for high density data storage and imaging.
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  10. Cruise, Gregory M.; Constant, Michael J.; Garretson, Joshua, Polymeric treatment compositions.
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  11. Cruise, Gregory M.; Constant, Michael J.; Garretson, Joshua, Polymeric treatment compositions.
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  12. Cruise, Gregory M.; Constant, Michael J.; Garretson, Joshua, Polymeric treatment compositions.
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  13. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Greene, Rob; Harris, Clayton, Polymeric treatment compositions.
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  14. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Greene, Rob; Harris, Clayton, Polymeric treatment compositions.
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  15. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Greene, Rob; Harris, Clayton, Polymeric treatment compositions.
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  16. Wackett, Lawrence P.; Aksan, Alptekin; Sadowsky, Michael J; Reategui, Eduardo; Kasinkas, Lisa, Silica encapsulated biomaterials.
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  17. Crall, Craig W., Sliding valve assembly.
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  18. Novak, Paige J.; Arnold, William Alan; Aksan, Alptekin, System and membrane for wastewater-generated energy and gas.
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  19. Guan, Jianjun; Wagner, William R.; Fujimoto, Kazuro Lee, Thermoresponsive, biodegradable, elastomeric material.
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  20. Martin, Stephanie M.; Huang, Lei; Yang, Shu-Ping; Huang, Yanbin; Villanueva, Julie; Greene, Sharon Linda; Arehart, Kelly; Sayre, Curtis; Johnson, Robert B., Vaginal treatment composition containing xylitol.
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  21. Yang, Shu Ping; Huang, Lei; Martin, Stephanie M.; Villanueva, Julie; Greene, Sharon; Arehart, Kelly; Sayre, Curtis; Johnson, Robert B., Xylitol for treatment of vaginal infections.
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