Systems and methods for freezing and storing biopharmaceutical material
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B65D-025/00
F25D-025/00
F25B-029/00
출원번호
US-0724793
(2003-12-01)
발명자
/ 주소
Voute,Nicolas
Lok,Maxime N.
Leonard,Leonidas Cartwright
Hughes,Timothy Gerard
Wisniewski,Richard
출원인 / 주소
Integrated Biosystems, Inc.
대리인 / 주소
Heslin Rothenberg Farley &
인용정보
피인용 횟수 :
10인용 특허 :
98
초록▼
The present invention provides a system for freezing, thawing, and storing biopharmaceutical materials which includes a flexible container, a conduit, and a temperature control unit. The flexible container is adapted to receive a biopharmaceutical material therein for freezing, thawing, and storing.
The present invention provides a system for freezing, thawing, and storing biopharmaceutical materials which includes a flexible container, a conduit, and a temperature control unit. The flexible container is adapted to receive a biopharmaceutical material therein for freezing, thawing, and storing. The container is formed of a first substantially flat sheet of flexible material joined together by a seam with a second substantially flat sheet of flexible material so as to lie substantially flat when empty. The container fully encloses an interior portion for receiving the biopharmaceutical material. Also, the container is configured to form a three dimensional shape when filled with the biopharmaceutical material, wherein the three dimensional shape has a first side and a second side opposite the first side. The conduit is connected to the flexible container with the outside of the container being in fluid communication with the interior portion via the conduit. The temperature control unit includes a first surface and a second surface facing the first surface and the temperature control unit is configured to receive the flexible container therein, when the container is filled with the biopharmaceutical material. The container conforms to the shape of the interior of the temperature control unit and the first side and the second side of the container contact the first surface and the second surface of the temperature control unit. The first surface and/or the second surface of temperature control unit include heat transfer surface(s).
대표청구항▼
What is claimed is: 1. A container or freezing, storing and thawing a biopharmaceutical material, which is receivable in a temperature control unit, said container comprising: a container material having an exterior contact area and an interior configured to receive the biopharmaceutical material t
What is claimed is: 1. A container or freezing, storing and thawing a biopharmaceutical material, which is receivable in a temperature control unit, said container comprising: a container material having an exterior contact area and an interior configured to receive the biopharmaceutical material therein for freezing, storing and thawing; said container material connectable to a support member having a handle, said support member configured to support a weight of said container material in response to said support member being connected to said container material, said support member being received on a support structure in the temperature control unit and said interior receiving the biopharmaceutical material; and said support member being configured to support said container material within the temperature control unit allow said contact area to contact a heat transfer surface separate from said support member to allow heat transfer between said heat transfer surface and the biopharmaceutical material. 2. The container of claim 1 wherein said support member is configured to support the container within a channel of a transportation cart in response to said support member being received on a support structure of the transportation cart. 3. The container of claim 1 wherein said container material forms a biopharmaceutical container which comprises a vertical dimension greater than a horizontal dimension in response to said biopharmaceutical container being received in an interior of the temperature control unit. 4. The container of claim 1 further comprising a port to provide fluid communication between said interior of said container material and an exterior of said container material. 5. The container of claim 1 wherein said handle is configured to allow a user to manipulate said container material holding the biopharmaceutical material. 6. The container of claim 1 wherein said support member is configured to support said container material to allow said contact area to be exposed to a contacting surface moveable relative to said container material to cause the heat transfer surface to contact said container material. 7. The container of claim 1 wherein said support member comprises at least one of a holder and a frame top to support said container material on the support structure of the temperature control unit. 8. The container of claim 1 wherein said container material comprises at least one of a flexible material and a semi-rigid material. 9. A system for freezing, storing and thawing a biopharmaceutical material, said system comprising: a container having an exterior contact area and being configured to receive the biopharmaceutical material therein; a support member having a handle, said support member connectable to said container and configured to be received on at least one support structure within a temperature control unit, said support member configured to support a weight of said container to allow a heat transfer surface of the temperature control unit, separate from the support member, to contact said contact area to allow heat transfer between the heat transfer surface and the biopharmaceutical material in response to said support member being connected to the container, said support member being received on the at least one support structure in the temperature control unit and the biopharmaceutical material being received in said container. 10. The system of claim 9 wherein said support member is configured to support said container on at least one of a plurality of channel supports of a transportation cart and a plurality of rails of a walk-in freezer. 11. The system of claim 9 wherein said container comprises at least one aperture, said support member further comprises at least one post projecting from said support member, and wherein said at least one aperture is adapted to receive said at least one post to allow said support member to support said container. 12. The system of claim 11 wherein said support member further comprises a capture member for sandwiching said container between said capture member and said support member about said at least one post. 13. The system of claim 11 further comprising a capture member pivotally connected to said support member, wherein said capture member comprises at least one opening configured to receive said at least one post to connect said capture member, said container, and said at least one post. 14. The system of claim 9 wherein said support member is configured to support said container in the temperature control unit and in a storage unit. 15. The system of claim 14 wherein said container comprises a thickness and at least one of a receiving portion of said temperature control unit and a receiving portion of said storage unit comprise at least one channel and said thickness is dimensioned to allow said container to be received in said at least one channel. 16. The system of claim 9 wherein said container is compressible within a width dimension of said support member. 17. The system of claim 9 wherein said container comprises at least one of a flexible container and a semi-rigid container. 18. A method for freezing, storing and thawing a biopharmaceutical material, the method comprising: providing a container having an exterior contact area and an interior configured to contain the biopharmaceutical material for freezing, storing and thawing; coupling a support member having a handle to the container, the support member being configured to support a weight of the container in response to the support member being received on a support structure of a temperature control unit and the interior receiving the biopharmaceutical material; and supporting the container within the temperature control unit on the support member to allow the contact area to be exposed to a heat transfer surface separate from the support member to allow heat transfer between the heat transfer surface and the biopharmaceutical material. 19. The method of claim 18 further comprising receiving the support member on a support structure of a transportation cart to allow the container to be received in a channel of the transportation cart. 20. The method of claim 18 further comprising configuring the container to allow the container to be compressed within a width dimension of the support member. 21. The method of claim 18 further comprising connecting a port to the container to provide fluid communication between the interior of the container and an exterior of the container. 22. The method of claim 18 wherein the container comprises at least one aperture configured to receive at least one post projecting from the support member. 23. The method of claim 18 further comprising forming the container of at least one of a flexible material and a semi-rigid material.
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