Process for improving sucralose purity and yield
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C07H-013/02
C07H-013/00
출원번호
US-0092730
(2002-03-08)
발명자
/ 주소
Catani,Steven J.
Wiley,James E.
Vernon,Nicholas M.
Merkel,Carolyn M.
Micinski,Edward
출원인 / 주소
Tate &
Lyle Public Limited Company
대리인 / 주소
RatnerPrestia
인용정보
피인용 횟수 :
19인용 특허 :
32
초록▼
This invention relates to processes for purifying sucralose by the use of an initial non-crystallization purification procedure followed by three or more sequential crystallization steps and recycle of the mother liquor remaining from each crystallization step to the feed of another crystallization
This invention relates to processes for purifying sucralose by the use of an initial non-crystallization purification procedure followed by three or more sequential crystallization steps and recycle of the mother liquor remaining from each crystallization step to the feed of another crystallization or purification step. This invention also relates to sucralose compositions as well as compositions comprising the sucralose compositions of the present invention. These compositions may be highly pure and have a superior taste profile.
대표청구항▼
What is claimed is: 1. A method of obtaining sucralose from a feed mixture comprising 6-O-acyl-4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose, other chlorinated sucrose byproducts, and optionally other blocked or partially blocked chlorinated sucrose byproducts comprising the steps of: (a) purify
What is claimed is: 1. A method of obtaining sucralose from a feed mixture comprising 6-O-acyl-4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose, other chlorinated sucrose byproducts, and optionally other blocked or partially blocked chlorinated sucrose byproducts comprising the steps of: (a) purifying said feed mixture to obtain an increased purity sucralose precursor stream containing a total amount of said other chlorinated sucrose byproducts and said other blocked or partially blocked chlorinated sucrose byproducts, relative to 6-O-acyl-4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose, that is lower than a total amount of said other chlorinated sucrose byproducts and said other blocked or partially blocked chlorinated sucrose byproducts, relative to 6-O-acyl-4,1',6'-trichloro-4,1'6'-trideoxygalactosucrose, in the feed mixture; said purifying comprising a non-crystallization extraction step; (b) converting said 6-O-acyl-4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose in said increased purity sucralose precursor stream to sucralose; (c) crystallizing said sucralose to obtain a crystalline sucralose and a mother liquor; and (d) performing at least three additional sequential crystallizations of said crystalline sucralose to obtain a substantially pure sucralose and additional mother liquor. 2. The method of claim 1, said purifying further comprising, after said non-crystallization extraction step, the step of crystallizing 6-O-acyl-4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose to provide the increased purity sucralose precursor stream. 3. The method of claim 1, wherein said crystallizing step is performed three times. 4. The method of claim 1, wherein said crystallizing step is performed four times. 5. The method of claim 1, wherein said crystallizing step is performed five times. 6. The method of claim 1, wherein said crystallizing step is performed more than five times.
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이 특허에 인용된 특허 (32)
Lee Cheang K. (Singapore SGX), 4′-Halo-substituted sucrose derivatives.
Richard L. Barndt ; Shyhyuan Liao ; Carolyn M. Merkel ; William J. Chapello ; Juan L. Navia, Low calorie, palatable fiber-containing, sugar substitute.
Bornemann Stephen (Leamington Spa GB3) Cassells John M. (St. Ives GB3) Combes Clive L. (Reading IA GB3) Dordik Jonathan S. (Iowa City IA) Hacking Andrew J. (Mortimer GB3), Preparation of acylated sucrose derivatives.
Vernon, Nicholas M.; Walkup, Robert E., Process for recovery of organotin esters from reaction mixtures containing the same and re-use of the recovered organotin compounds.
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Prakash, Indra; DuBois, Grant E., High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith.
Kerr, John; Jansen, Robert; Leinhos, Duane A.; Wiley, Jr., James Edwin; Camborieux, Sebastien; Baiada, Anthony; Walker, Gordon; Maffezzoni, Carlo, Method for the production of sucralose.
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