초록 ▼

A channel (140) is divised into portions (142, 144). The sidewalls of each channel portion (142, 144) have surface charges of opposite polarity. The two channel portions (142, 144) are physically connected together by a salt bridge (133), such as a glass frit or gel layer. The salt bridge (133) sepa

A channel (140) is divised into portions (142, 144). The sidewalls of each channel portion (142, 144) have surface charges of opposite polarity. The two channel portions (142, 144) are physically connected together by a salt bridge (133), such as a glass frit or gel layer. The salt bridge (133) separates the fluids in channel (140) from an ionic fluid reservoir ( 135). To impart electroosmotic and electrophoretic forces along the channel (140) between parts A and B, respectively. Additionally, a third electrode (137) is placed in the reservoir (135).

대표청구항 ▼

What is claimed is: 1. A microfluidic device comprising: a planar substrate having at least a first microfluidic channel disposed therein, the first microfluidic channel having at least one cross-sectional dimension of less than about 100 microns; and a pipettor extending from the substrate and hav

What is claimed is: 1. A microfluidic device comprising: a planar substrate having at least a first microfluidic channel disposed therein, the first microfluidic channel having at least one cross-sectional dimension of less than about 100 microns; and a pipettor extending from the substrate and having a first capillary channel disposed therein, the first capillary channel having at least one cross-sectional dimension of less than about 100 microns and being fluidly connected at a first end to the first microfluidic channel. 2. The microfluidic device of claim 1, wherein the pipettor comprises a capillary tube. 3. The microfluidic device of claim 1, wherein the substrate comprises at least first and second interconnected microfluidic channels disposed therein. 4. The microfluidic device of claim 1, wherein the pipettor is formed from at least a portion of the substrate. 5. The microfluidic device of claim 1, wherein the substrate comprises glass. 6. The microfluidic device of claim 1, wherein the substrate comprises a polymeric material. 7. The microfluidic device of claim 1, wherein the capillary channel has a cross-sectional dimension of between about 1 and about 50 μm. 8. The microfluidic device of claim 1, wherein the pipettor comprises an electropipettor. 9. The microfluidic device of claim 1, wherein the capillary channel has a cross-sectional area of between about 10 and about 1000 μ m2. 10. The microfluidic device of claim 1, wherein the capillary channel has a cross-sectional area of between about 10 and about 100 μ m2. 11. The microfluidic device of claim 1, wherein the capillary channel has a diameter of about 30 μm. 12. The microfluidic device of claim 1, wherein the substrate comprises at least three or more intersecting microfluidic channels disposed therein.