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Fused cyclic modulators of nuclear hormone receptor function

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07D-471/08
  • C07D-471/00
  • C07D-471/18
  • C07D-487/08
  • C07D-487/00
  • A61K-031/439
  • A61P-035/00
출원번호 US-0322306 (2002-12-18)
발명자 / 주소
  • Salvati,Mark E.
  • Balog,James Aaron
  • Shan,Weifang
  • Giese,S철ren
  • Harikrishnan,Lalgudi S.
출원인 / 주소
  • Bristol Myers Squibb Company
인용정보 피인용 횟수 : 17  인용 특허 : 84

초록

The invention pertains to fused cyclic compounds having the formula, wherein G is an optionally substituted aryl or heterocyclo, L is an optional linker, M is a bond, O, CR7R7' or NR10 , and M' is a bond or NR10, with the proviso that at least one of M or M' must be a bond; E is C═Z2, CR7CR

대표청구항

We claim: 1. A compound selected from the group consisting of: (5α ,8α,8aα)-8,8a-Dihydro-2-[3-(trifluoromethyl)phenyl]-5,8-methanoimidazo[1,5-a]pyridine-1,3(2H,5H)-dione; (5α,8α, 8aα)-2,3,8,8a-Tetrahydro-2-[3-(trifluoromethyl)phenyl]-3-thioxo-5,8-methanoimidazo[1,5-a]p

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이 특허를 인용한 특허 (17)

  1. Shan,Weifang; Balog,James Aaron; Nation,Andrew James; Gavai,Ashvinikumar V.; Han,Wen Ching; Salvati,Mark E., Alkylene bridged sultam compounds useful as modulators of nuclear hormone receptor function.
  2. Dalton, James T.; Herring, Christina; Miller, Duane D.; Hong, Seoung-Soo; He, Yali; Mohler, Michael L.; Narayanan, Ramesh; Wu, Zhongzhi, Estrogen receptor ligands and methods of use thereof.
  3. Dalton, James T.; Steiner, Mitchell S.; Coss, Christopher C.; Getzenberg, Robert H., Estrogen receptor ligands and methods of use thereof.
  4. Dalton, James T.; Steiner, Mitchell S.; Eswaraka, Jeetendra, Estrogen receptor ligands and methods of use thereof.
  5. Dalton, James T.; Steiner, Mitchell S.; Eswaraka, Jeetendra, Estrogen receptor ligands and methods of use thereof.
  6. Dalton, James T.; Steiner, Mitchell S.; Morton, Ronald A., Estrogen receptor ligands and methods of use thereof.
  7. Salvati, Mark E.; Attar, Ricardo M.; Gottardis, Marco M.; Balog, James Aaron; Pickering, Dacia A.; Martinez, Rogelio L.; Sun, Chongqing, Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function.
  8. Salvati,Mark E.; Balog,James Aaron, Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function.
  9. Salvati,Mark E.; Balog,James Aaron; Pickering,Dacia A.; Zhu,Hong, Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function.
  10. Shan, Weifang; Balog, James Aaron; Gavai, Ashvinikumar V.; Zhao, Yufen, Fused heterocyclic compounds useful as modulators of nuclear hormone receptor function.
  11. Salvati,Mark E.; Misra,Raj N., Fused heterocyclic imido and amido compounds.
  12. Salvati, Mark E.; Balog, James Aaron; Pickering, Dacia A.; Giese, Sören; Fura, Aberra; Li, Wenying; Patel, Ramesh N.; Hanson, Ronald L.; Mitt, Toomas; Roberge, Jacques Y.; Corte, James R.; Spergel, Steven H.; Rampulla, Richard A.; Misra, Raj N.; Xiao, Hai Yun, Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function.
  13. Salvati, Mark E.; Balog, James Aaron; Pickering, Dacia A.; Giese, Sören; Fura, Aberra; Li, Wenying; Patel, Ramesh N.; Hanson, Ronald L.; Mitt, Toomas; Roberge, Jacques Y.; Corte, James R.; Spergel, Steven H.; Rampulla, Richard A.; Misra, Raj N.; Xiao, Hai-Yun, Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function.
  14. Labrie, Fernand; Singh, Shankar Mohan; Labrecque, Richard; Ciobanu, Liviu Constantin, Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety.
  15. Dalton, James T.; Barrett, Christina; He, Yali; Hong, Seoung-Soo; Miller, Duane D.; Mohler, Michael L.; Narayanan, Ramesh; Wu, Zhongzhi, Nuclear receptor binding agents.
  16. Dalton, James T.; Barrett, Christina; Miller, Duane D.; Hong, Seoung-Soo; He, Yali; Mohler, Michael L.; Narayanan, Ramesh; Wu, Zhongzhi, Nuclear receptor binding agents.
  17. Henriksen,Dennis Bang; Holst,Jens Juul, Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes.
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