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Microfabricated elastomeric valve and pump systems 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • F16K-031/126
출원번호 US-0796871 (2001-02-28)
발명자 / 주소
  • Unger,Marc A.
  • Chou,Hou Pu
  • Thorsen,Todd A.
  • Scherer,Axel
  • Quake,Stephen R.
출원인 / 주소
  • California Institute of Technology
대리인 / 주소
    Townsend and Townsend and Crew LLP
인용정보 피인용 횟수 : 44  인용 특허 : 43

초록

A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a se

대표청구항

What is claimed is: 1. A method of actuating an elastomeric structure comprising: providing an elastomeric block formed from a first cured elastomeric layer with a first microfabricated recess adapted to direct a flow of fluid therein, and a second cured elastomeric layer with a second microfabrica

이 특허에 인용된 특허 (43)

  1. Sanjoh Akira,JPX, Apparatus for crystal growth and crystal growth method employing the same.
  2. Usami Ron (Komae JPX) Nagaoka Shunji (Tsukuba JPX) Udaka Tsutomu (Tokyo JPX) Kawasaki Kazunori (Kawagoe JPX) Muramatsu Shoji (Houya JPX), Crystal growing cell.
  3. Sanjoh Akira,JPX, Crystallization control method for organic compound and crystallization control solid-state component employed therefor.
  4. DeTitta George T. (Kenmore NY) Luft Joseph R. (Kenmore NY), Device for growing crystals.
  5. Carter Stephen,CAX, Digital gas metering system using tri-stable and bi-stable solenoids.
  6. Yamazaki ; Toru, Elastomer display device.
  7. Whitehead Lorne A. (Vancouver CAX) Bolleman Brent J. (Vancouver CAX), Elastomeric micro electro mechanical systems.
  8. Horres ; Jr. Charles R. (Del Mar CA), Electrochemical controlled dispensing assembly and method for selective and controlled delivery of a dispensing fluid.
  9. Cabuz Cleopatra, Electrostatically actuated mesopump having a plurality of elementary cells.
  10. Naruse Yoshihiro (Ichikawa JPX) Ando Mitsuhiro (Tokyo JPX) Mizuno Tomokimi (Ichikawa JPX) Nakajima Naomasa (Tokyo JPX), Fluid flow regulating device.
  11. Parce John Wallace ; Kopf-Sill Anne R. ; Bousse Luc J., High throughput screening assay systems in microscale fluidic devices.
  12. Surjaatmadja Jim B. (Duncan OK), Hydraulic digital stepper actuator.
  13. Lipshutz Robert J. ; Rava Richard P. ; Anderson Rolfe C. ; Fodor Stephen P. A., Integrated nucleic acid diagnostic device.
  14. Feingold Robert M. (Annandale VA), Method of making a plate having a pattern of microchannels.
  15. Santarsiero Bernard D. ; Stevens Raymond C. ; Shultz Peter G. ; Jaklevic Joseph M. ; Yegian Derek T. ; Cornell Earl ; Nordmeyer Robert A. ; Jin Jian ; Kolbe William F. ; Jones Arthur L. ; Uber Donald, Methods and apparatus for performing array microcrystallizations.
  16. Young Robert M. (Pittsburgh PA) Freidhoff Carl B. (Murrysville PA), Micro-miniature diaphragm pump for the low pressure pumping of gases.
  17. Zengerle Roland (Mnchen DEX) Richter Axel (Mnchen DEX), Micro-miniaturized, electrostatically driven diaphragm micropump.
  18. Faris Sadeg M. (24 Pocantico River Rd. Pleasantville NY 10570) Jain Kanti (18 Algonquian Trail Briarcliff Manor NY 10510), Microchannel plate technology.
  19. Weinberg Marc S. (Needham MA), Microfabricated pump.
  20. Moles Donald R., Microfluidic analyzer module.
  21. Ekstrm Bjrn (Upsala SEX) Jacobson Gunilla (Upsala SEX) Ohman Ove (Upsala SEX) Sjdin Hakan (Upsala SEX), Microfluidic structure and process for its manufacture.
  22. Kopf-Sill Anne R. ; Parce John Wallace, Microfluidic systems incorporating varied channel dimensions.
  23. Hartley Frank T., Micromachined peristaltic pump.
  24. Hartley Frank T., Micromachined peristaltic pumps.
  25. Huff Michael A. (Medford MA) Schmidt Martin A. (Reading MA), Micromachined threshold pressure switch and method of manufacture.
  26. Richter Axel (Mnchen DEX), Microminiaturized pump.
  27. Van Lintel Harald,CHX, Micropump.
  28. van Lintel Harald (Martigny CHX), Micropump having a constant output.
  29. Kamisuki Shinichi (Suwa JPX) Nose Yasuto (Suwa JPX) Shimizu Nobuo (Suwa JPX) Yotsuya Shinichi (Suwa JPX), Micropump with valve structure.
  30. Forster Fred K. ; Bardell Ronald L. ; Blanchard Alan P. ; Afromowitz Martin A. ; Sharma Nigel R., Micropumps with fixed valves.
  31. Lisec Thomas (Berlin DEX) Quenzer Hans-Joachim (Berlin DEX) Wagner Bernd (Berlin DEX), Microvalve.
  32. Bouteille Daniel (Ville d\Avray FRX) Duclos Michel (Verneuil l\Etang FRX) Marguet Hugues (Paris FRX) Nicolas Michel (Plaisir FRX) Petrimaux Eric (Evreux FRX), Pneumatic logic circuit.
  33. Pegourie Jean-Pierre (3 Passage Bruyas 34000 Montpellier FR), Pneumatic logic circuits and their integrated circuits.
  34. Faste Rolf A. (Stanford CA), Portable infusion device assembly.
  35. Fujita Shozo (Atsugi JPX) Asano Koji (Ebina JPX) Hashitani Takafumi (Atsugi JPX), Process and apparatus for preparation of single crystal of biopolymer.
  36. Trah Hans-Peter (Reutlingen DEX), Thermal micropump with values formed from silicon plates.
  37. Zachary Bryan A. ; Summers Angela E., Two out of three voting solenoid arrangement.
  38. van Lintel Harald T. G. (Enschede NLX), Two valve micropump with improved outlet.
  39. Miyazaki Hajime (Suwa JPX) Handa Masaaki (Suwa JPX) Uehara Taisuke (Suwa JPX) Muranaka Tsukasa (Suwa JPX) Kamisuki Shinichi (Suwa JPX) Nose Yasuto (Suwa JPX), Two-valve thin plate micropump.
  40. Pan Jeffrey Y. ; Lee Donald Ver, Valve control.
  41. Kamen Dean L. (44 Gage Rd. Bedford NH 03102), Valve system with removable fluid interface.
  42. Webster Milo E. (Yarmouth Port MA), Valve with flexible sheet member and two port non-flexing backer member.
  43. Hansson Thord (Balinge SEX) Sjolander Stefan (Uppsala SEX), Valve, especially for fluid handling bodies with microflowchannels.

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  4. Maltezos, George; Scherer, Axel, Control arrangement for microfluidic devices and related methods and systems.
  5. Stojanov, Tomas, Cryopreservation of biological cells and tissues.
  6. Levchenko, Andre; Cheong, Raymond; Wang, Chiaochun J., Device for high-throughput stimulation, immunostaining, and visualization of single cells.
  7. Pattekar, Ashish; Chow, Eugene M.; Peeters, Eric, Electrostatically addressable microvalves.
  8. Pattekar, Ashish; Chow, Eugene M; Peeters, Eric, Electrostatically addressable microvalves.
  9. Van Dam, Robert Michael; Ball, Carroll Edward; Elizarov, Arkadij M.; Kolb, Hartmuth C., Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography.
  10. Li, Zhenyu; Psaltis, Demetri; Scherer, Axel; Zhang, Zhaoyu, Mechanically tunable elastomeric optofluidic distributed feedback dye lasers.
  11. Putnam, Martin A.; Kersey, Alan D., Method and apparatus for performing assays.
  12. Heath, James R.; Van Dam, Michael; Elizarov, Arkadij, Method and apparatus for the mechanical actuation of valves in fluidic devices.
  13. Bao, Xiaoyan Robert; Quake, Stephen R.; Simon, Melvin I., Method and device for regulating fluid flow in microfluidic devices.
  14. Vom, Eduardo; Roy, Tammie Kim; Lewis, Craig Matthews; Hobbs, Benjamin Rawlingson; Hobbs, Simon James, Method, system and apparatus for improved micromanipulation and storage.
  15. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays.
  16. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results.
  17. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O.; Tu, Jane M., Micro-tube particles for microfluidic assays and methods of manufacture.
  18. Unger, Marc A.; Chou, Hou-Pu; Thorsen, Todd A.; Scherer, Axel; Quake, Stephen R., Microfabricated elastomeric valve and pump systems.
  19. Unger, Marc A.; Chou, Hou-Pu; Thorsen, Todd A.; Scherer, Axel; Quake, Stephen R., Microfabricated elastomeric valve and pump systems.
  20. Putnam, Martin A., Microfluidic assay assemblies and methods of manufacture.
  21. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Microfluidic assay operating system and methods of use.
  22. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Microfluidic assay systems employing micro-particles and methods of manufacture.
  23. Elizarov, Arkadij M.; Kolb, Hartmuth C.; Van Dam, R. Michael; Heath, James R., Microfluidic chip capable of synthesizing radioactively labeled molecules on a scale suitable for human imaging with positron emission tomography.
  24. Elizarov, Arkadij M; Kolb, Hartmuth C.; Van Dam, R. Michael; Heath, James R., Microfluidic chip capable of synthesizing radioactively labeled molecules on a scale suitable for human imaging with positron emission tomography.
  25. Hansen, Carl Lars Genghis; Tropini, Carolina, Microfluidic device and method of using same.
  26. Levchenko, Andre; Groisman, Alexander; Paliwal, Saurabh, Microfluidic device for high-throughput cellular gradient and dose response studies.
  27. Kenis, Paul J. A.; Tice, Joshua D.; Perry, Sarah L.; Roberts, Griffin W., Microfluidic device for preparing mixtures.
  28. Wang, Jing; Woudenberg, Timothy M., Microfluidic device regeneration.
  29. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Microfluidic devices and methods of manufacture and use.
  30. Maltezos, George; Scherer, Axel, Microfluidic devices and related methods and systems.
  31. Elizarov, Arkadij; Heath, James R.; Kolb, Hartmuth; van Dam, Michael, Microfluidic method and structure with an elastomeric gas-permeable gasket.
  32. Henderson, Chester John; Lewis, Craig Matthew; Roy, Tammie Kim; Vom, Eduardo, Micromanipulation and storage apparatus and methods.
  33. Mayer, Felix, Multicellular pump and fluid delivery device.
  34. Mayer, Felix, Multicellular pump and fluid delivery device.
  35. Axelrod, Blake Waters; Popescu, Paula; Roukes, Michael L., NEMS sensors for cell force application and measurement.
  36. Putnam, Martin A.; Leamon, John H.; Branciforte, Jeffrey T.; Stanwood, Charles O., PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use.
  37. DeSimone, Joseph M.; Rolland, Jason P.; Quake, Stephen R.; Schorzman, Derek A.; Yarbrough, Jason; Van Dam, Michael, Photocurable perfluoropolyethers for use as novel materials in microfluidic devices.
  38. Roukes, Michael L.; Fon, Chung-Wah; Lee, Wonhee; Tang, Hongxing; Axelrod, Blake Waters; Tan, John Liang, Polymer NEMS for cell physiology and microfabricated cell positioning system for micro-biocalorimeter.
  39. Roukes, Michael L.; Fon, Chung-Wah; Lee, Wonhee; Tang, Hongxing; Axelrod, Blake Waters; Tan, John Liang, Polymer NEMs for cell physiology and microfabricated cell positioning system for micro-biocalorimeter.
  40. Putnam, Martin A., Portable microfluidic assay devices and methods of manufacture and use.
  41. Elizarov, Arkadij M.; Ball, Carroll Edward; Zhang, Jianzhong; Kolb, Hartmuth C.; Van Dam, R. Michael; Diener, Lawrence; Ford, Sean; Miraghaie, Reza, Portable microfluidic radiosynthesis system for positron emission tomography biomarkers and program code.
  42. Stanwood, Charles; Daigneault, Noel; Branciforte, Jeffrey, Segmented multi-use automated assay cartridge.
  43. Blainey, Paul; Kim, Soohong, Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte.
  44. Blainey, Paul; Kim, Soohong, Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte.
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