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High viscosity liquid controlled delivery system and medical or surgical device 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-013/02
  • C07H-013/00
  • C07D-309/00
출원번호 US-0699002 (2000-10-26)
발명자 / 주소
  • Gibson,John W.
  • Tipton,Arthur J.
출원인 / 주소
  • Durect Corporation
인용정보 피인용 횟수 : 63  인용 특허 : 28

초록 ▼

The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a controlled fashion, and for use as medical or surgical devices. The materials can optionally be diluted with a so

대표청구항 ▼

What is claimed is: 1. A compound having a structure selected from the group consisting of: wherein R1, R2, R3, R4, and R5 are independently selected from the group consisting of hydrogen, hydroxy-substituted alkanoyl having 2 to 6 carbons, and acyloxy-substituted alkanoyl having 2 to 6 carbons,

이 특허에 인용된 특허 (28)

  1. Duan Daniel C. ; Stefely James S. ; Schultz David W. ; Leach Chester L., Aerosol formulation containing a diol-diacid derived dispersing aid.
    상세보기
  2. Duan Daniel C. (St. Paul MN) Stefely James S. (Woodbury MN) Schultz David W. (Pine Springs MN) Leach Chester L. (Lake Elmo MN), Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid.
    상세보기
  3. Duan Daniel C. ; Stefely James S. ; Schultz David W. ; Leach Chester L., Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid.
    상세보기
  4. Patel Rajesh (San Mateo CA) Bowman Lyle (Pleasanton CA) Vildaver Margarita (Napa CA) Chen Raymond (Union City CA), Alkaline ophthalmic suspensions.
    상세보기
  5. Noda Kanji (Chikushino JPX) Nakagawa Akira (Tosu JPX) Haraguchi Yasushi (Kamimine JPX) Ueda Koichiro (Tosu JPX) Hirano Munehiko (Tosu JPX) Nishioka Itsuo (Fukuoka JPX) Yagi Akira (Kasuya JPX) Koda Ak, Alkyl-ketohexopyranoside derivatives and method of use.
    상세보기
  6. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods for producing the same.
    상세보기
  7. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  8. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  9. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  10. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David D., Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  11. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David P., Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  12. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
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  13. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
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  14. Langer Robert S. (Somerville MA) Rosen Howard (Montara CA), Bioerodible polyanhydrides for controlled drug delivery.
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  15. Langer Robert S. (Somerville MA) Rosen Howard (Montara CA) Linhardt Robert J. (Iowa City IA) Leong Kam (Cambridge MA), Bioerodible polyanhydrides for controlled drug delivery.
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  16. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions.
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  17. della Valle Francesco (Padova ITX) Romeo Aurelio (Rome ITX), Cross-linked esters of hyaluronic acid.
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  18. Tipton Arthur J. ; Holl Richard J., High viscosity liquid controlled delivery system.
    상세보기
  19. Brooks Norman D. (5923 E. 300 N. Greenfield IN 46140) Needham Gregory F. (1203 Sherwood Dr. Greenfield IN 46140), Injectable extended release formulations and methods.
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  20. Tice Thomas R. (Birmingham AL) Lewis Danny H. (Gardendale AL) Cowsar Donald R. (Birmingham AL) Beck Lee R. (Birmingham AL), Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents.
    상세보기
  21. Cohen Smadar (Petach-Tickva ILX) Bano Carmen (Valencia PA ESX) Visscher Karyn B. (State College PA) Chow Marie (Brookline MA) Allcock Harry R. (State College PA) Langer Robert S. (Newton MA), Ionically cross-linked polymeric microcapsules.
    상세보기
  22. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J., Liquid delivery compositions.
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  23. Yewey Gerald L. ; Krinick Nancy L. ; Dunn Richard L. ; Radomsky Michael L. ; Brouwer Gerbrand ; Tipton Arthur J., Liquid delivery compositions.
    상세보기
  24. Haynes Duncan H. (4051 Barbarossa Ave. Miami FL 33133), Method of inducing local anesthesia using microdroplets of a general anesthetic.
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  25. Haynes Duncan H. (4051 Barbarossa Ave. Miami FL 33133), Microdroplets of water-insoluble drugs and injectable formulations containing same.
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  26. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO), Polymeric compositions useful as controlled release implants.
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  27. Kikuchi Yukio (Osaka JPX) Kamaguchi Ryosei (Osaka JPX), Seamless capsule and process for producing the same.
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  28. Yamagata Yutaka,JPX ; Iga Katsumi,JPX ; Okada Hiroaki,JPX, Sustained releasable parenteral pharmaceutical preparations and method of producing the same.
    상세보기

이 특허를 인용한 특허 (63)

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  3. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
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  4. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn, Compositions of a polyorthoester and an aprotic solvent.
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  5. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn, Compositions of a polyorthoester and an aprotic solvent.
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  6. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn; Niemann, Joseph, Compositions of a polyorthoester and an aprotic solvent.
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  7. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn; Niemann, Joseph, Compositions of a polyorthoester and an aprotic solvent.
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  8. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
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  9. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
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  10. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
    상세보기
  11. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
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  12. Verity, A. Neil, Controlled delivery system.
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  13. Verity, A. Neil, Controlled delivery system.
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  14. Verity, A. Neil, Controlled delivery system.
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  15. Verity, A. Neil, Controlled delivery system.
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  16. Tipton, Arthur J.; Burton, Kevin W., Elastic implantable composites and implants comprising same.
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  17. Tice, Thomas R., Flexible implantable composites and implants comprising same.
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  18. Dwyer, John; Bray, Brian L.; Schneider, Stephen E.; Zhang, Huyi; Tvermoes, Nicolai A.; Johnston, Barbara E.; Friedrich, Paul E., HIV fusion inhibitor peptides with improved biological properties.
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  19. Dwyer,John; Bray,Brian L.; Schneider,Stephen E.; Zhang,Huyi; Tvermores,Nikolai A.; Johnston,Barbara E.; Friedrich,Paul E., HIV fusion inhibitor peptides with improved biological properties.
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  20. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark Alexander; Halliday, Janet Anne, Hydrophilic polyurethane compositions.
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  21. Tuominen, Jukka; Zurutuza, Amaia; Livingstone, Mark; Halliday, Janet Anne, Hydrophilic polyurethane compositions.
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  22. Tipton, Arthur J.; Burton, Kevin W.; Bischoff, Thomas C.; Ferris, William V., Implantable composites and implants comprising same.
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  23. Tice, Thomas R., Implantable suction cup composites and implants comprising same.
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  24. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same.
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  25. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same.
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  26. Harder, Philipp; Fritz, Olaf; Fritz, Ulf, Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
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  27. Harder, Philipp; Fritz, Olaf; Fritz, Ulf, Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
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  28. Shen, Hui Rong; Gan, Na, Long-acting semi-solid lipid formulations.
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  29. Dunn, Richard L., Low viscosity liquid polymeric delivery system.
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  30. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C., Oral drug delivery system.
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  36. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C.; Fu, Roger; Zamloot, Michael S., Oral drug delivery system.
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  37. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C.; Fu, Roger; Zamloot, Michael S., Oral drug delivery system.
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