Substantially solid desensitizing compositions and devices having a tray-like configuration and methods of manufacturing and using such compositions and devices
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61C-015/00
A61K-009/20
출원번호
US-0637237
(2003-08-08)
발명자
/ 주소
Allred,Peter M.
Jessop,Neil T.
출원인 / 주소
Ultradent Products, Inc.
대리인 / 주소
Workman Nydegger
인용정보
피인용 횟수 :
13인용 특허 :
87
초록▼
Dental desensitizing compositions are in the shape of a dental tray or tray-like configuration, optionally in combination with a protective barrier layer. Shaped desensitizing compositions comprise a substantially solid dental desensitizing composition that has increased adhesiveness to teeth when m
Dental desensitizing compositions are in the shape of a dental tray or tray-like configuration, optionally in combination with a protective barrier layer. Shaped desensitizing compositions comprise a substantially solid dental desensitizing composition that has increased adhesiveness to teeth when moistened with saliva or water. The shape of the dental desensitizing composition facilitates placement of the composition over a person's teeth with substantially less manipulation compared to the use of initially flat strips. The substantially solid dental desensitizing composition becomes more adhesive when moistened with saliva or water, yet remains intact and coherent after the dental desensitizing composition is placed over a person's teeth during desensitizing, particularly when used in combination with a moisture-resistant barrier. The result is that the moistened dental desensitizing composition is able to reliably adhere against a user's teeth during a desensitizing procedure.
대표청구항▼
What is claimed is: 1. An article of manufacture for use in desensitizing a person's teeth, comprising: a substantially solid and coherent dental desensitizing composition having a tray-like configuration comprising a front side wall, a rear side wall, and a trough between said front and rear side
What is claimed is: 1. An article of manufacture for use in desensitizing a person's teeth, comprising: a substantially solid and coherent dental desensitizing composition having a tray-like configuration comprising a front side wall, a rear side wall, and a trough between said front and rear side walls, said dental desensitizing composition having a rigidity so as to maintain itself in the tray-like configuration absent external support, said desensitizing composition having increased adhesiveness to teeth when moistened by saliva or water, said desensitizing composition comprising: at least one dental desensitizing agent; and at least one tooth adhesion agent that forms a substantially solid matrix within which said dental desensitizing agent is dispersed and that at least partially contributes to said increased adhesiveness to teeth when said dental desensitizing composition is moistened by saliva or water. 2. An article of manufacture as defined in claim 1, said desensitizing composition being initially horseshoe shaped prior to use so that said desensitizing composition at least approximately conforms to a person's dental arch with minimal longitudinal shaping. 3. An article of manufacture as defined in claim 1, said desensitizing composition initially having a longitudinal curvature that is less than the curvature of a person's dental arch prior to use so that additional longitudinal curving of said desensitizing composition is required when said desensitizing composition is plated over a person's teeth. 4. An article of manufacture as defined in claim 1, said desensitizing composition initially having a substantially straight longitudinal profile prior to use so that longitudinal curving of said desensitizing composition is required when said desensitizing composition is placed over a person's teeth. 5. An article of manufacture as defined in claim 1, at least a portion of said trough having an approximate U-shaped cross section. 6. An article of manufacture as defined in claim 1, at least a portion of said trough having an approximate V-shaped cross section. 7. An article of manufacture as defined in claim 1, at least a portion of said trough having an approximate L-shaped cross section. 8. An article of manufacture as defined in claim 1, at least a portion of said trough having approximately a rectangular or trapezoidal cross section. 9. An article of manufacture as defined in claim 1, said dental desensitizing agent comprising at least one of potassium nitrate, potassium salt, citric acid, citrate, strontium chloride, sodium fluoride, or stannous fluoride. 10. An article of manufacture as defined in claim 1, said dental desensitizing agent having a concentration in a range of about 0. 01% to about 50% by weight of said desensitizing composition. 11. An article of manufacture as defined in claim 1, said dental desensitizing agent having a concentration in a range of about 0. 5% to about 25% by weight of said desensitizing composition. 12. An article of manufacture as defined in claim 1, said dental desensitizing agent having a concentration in a range of about 0. 1% to about 10% by weight of said desensitizing composition. 13. An article of manufacture as defined in claim 1, said tooth adhesion agent comprising polyvinyl pyrrolidone. 14. An article of manufacture as defined in claim 1, said tooth adhesion agent comprising at least one of carboxypolymethylene, polyethylene oxide, polyacrylic acid, copolymer of polyacrylic acid, polyacrylate, polyacrylamide, copolymer of polyacrylic acid and polyacrylamide, PVP-vinyl acetate copolymer, carboxymethylcellulose, carboxypropylcellulose, polysaccharide gum, or protein. 15. An article of manufacture as defined in claim 1, said tooth adhesion agent having a concentration in a range of about 10% to about 90% by weight of said desensitizing composition. 16. An article of manufacture as defined in claim 1, said tooth adhesion agent having a conceptration in a range of about 20% to about 80% by weight of said desensitizing composition. 17. An article of manufacture as defined in claim 1, said tooth adhesion agent having a concentration in a range of about 40% to about 75% by weight of said desensitizing composition. 18. An article of manufacture as defined in claim 1, said desensitizing composition further comprising at least one humectant. 19. An article of manufacture as defined in claim 1, wherein said desensitizing composition is sized and configured so as to fit over at least a portion of a person's upper dental arch. 20. An article of manufacture as defined in claim 1, wherein said desensitizing composition is sized and configured so as to fit over at least a portion of a person's lower dental arch. 21. An article of manufacture as defined in claim 1, wherein said desensitizing composition has a cross-sectional thickness in a range of about 0.1 mm to about 0.5 mm. 22. An article of manufacture as defined in claim 1, wherein said desensitizing composition has a cross-sectional thickness in a range of about 0.5 mm to about 2 mm. 23. An article of manufacture as defined in claim 1, wherein said desensitizing composition has a cross-sectional thickness in a range of about 2 mm to about 3 mm. 24. An article of manufacture as defined in claim 1, wherein said desensitizing composition is sized and configured so as to approximately terminate at or near a person's gingival margin when said denial desensitizing composition is in use. 25. An article of manufacture as defined in claim 1, wherein said desensitizing composition is contained within a sealed package prior to use. 26. An article of manufacture as defined in claim 1, further comprising a barrier layer comprising a moisture-resistant material adjacent to an outer surface of said desensitizing composition that protects the desensitizing composition firm saliva or moisture when in use. 27. An article of manufacture as defined in claim 26, said barrier layer being flexible so that it will readily conform to the shape of a person's teeth when in use. 28. An article of manufacture as defined in claim 26, said barrier layer comprising at least one polyolefin. 29. An article of manufacture as defined in claim 28, said polyolefin comprising at least one of polyethylene, high density polyethylene, low density polyethylene, ultra-low density polyethylene, polypropylene, or polytetrafluoroethylene. 30. An article of manufacture as defined in claim 26, said barrier layer comprising at least one of wax, metal foil, paraffin, ethylene-vinyl acetate copolymer, ethylene-vinyl alcohol copolymer, polycaprolactone, polyester, polycarbonate, polyurethane, polyatnide, or polyesteramide. 31. An article of manufacture as defined in claim 1, said desensitizing composition further comprising at least one dental bleaching agent. 32. An article of manufacture as defined in claim 31, said dental bleaching agent having a concentration in a range of about 5% to about 80% by weight of said desensitizing composition. 33. An article of manufacture as defined in claim 31, said dental bleaching agent having a concentration in a range of about 10% to about 60% by weight of said desensitizing composition. 34. An article of manufacture as defined in claim 31, said dental bleaching agent having a concentration in a range of about 20% to about 50% by weight of said desensitizing composition. 35. A kit for use in desensitizing a person's teeth comprising a plurality of substantially solid desensitizing compositions having a tray-like configuration according to claim 1. 36. An article of manufacture comprising a dental desensitization device for use in desensitizing a person's teeth, said dental desensitization device comprising: a barrier layer comprising a moisture-resistant material in the shape of a dental tray comprising a front side wall, a rear side wall, and a trough between said front and rear side walls; and a desensitizing layer within said trough comprising a substantially solid dental desensitizing composition having a first surface adjacent to said barrier layer and a second surface that has increased adhesiveness to teeth when moistened by saliva or water, said desensitizing layer being in the shape of a dental tray and having a rigidity so as to at least partially contribute to maintaining said dental desensitizing device in the shape of a dental tray prior to placing said desensitizing device aver a person's teeth said desensitizing composition comprising: at least one dental desensitizing agent; and at least one tooth adhesion agent that forms a substantially solid matrix within which said dental desensitizing agent is dispersed and that at least partially contributes to said increased adhesiveness to teeth when said dental desensitizing composition is moistened by saliva or water. 37. An article of manufacture as defined in claim 36, at least a portion of said trough having a cross section that is approximately U-shaped, V-shaped, L-shaped, rectangular, or trapezoidal. 38. An article of manufacture as defined in claim 36, said barrier layer being flexible so that it will readily conform to the shape of a person's teeth when in use. 39. An article of manufacture as defined in claim 36, said barrier layer comprising at least one polyolefin. 40. An article or manufacture as defined in claim 39, said polyolefin comprising at least one of polyethylene, high density polyethylene, low density polyethylene, ultra-low density polyethylene, polypropylene, or polytetrafluoroethylene. 41. An article of manufacture as defined in claim 36, said barrier layer comprising at least one of wax, metal foil, paraffin, ethylene-vinyl acetate copolymer, ethylene-vinyl alcohol copolymer, polycaprolactone, polyester, polycarbonate, polyurethane, polyamide, or polyesteramide. 42. An article of manufacture as defined in claim 36, said barrier layer having a rigidity so as to at least partially contribute to maintaining said dental desensitizing device in the shape of a dental tray prior to placing said desensitizing device over a person's teeth. 43. An article of manufacture as defined in claim 36, said barrier layer being initially horseshoe shaped prior to use so that said dental desensitizing device at least approximately conforms to a person's dental arch with minimal longitudinal shaping. 44. An article of manufacture as defined in claim 36, said barrier layer initially having a longitudinal curvature that is less than the curvature of a person's dental arch prior to use so that additional longitudinal curving of said dental desensitizing device is required when said dental desensitizing device is placed over a person's teeth. 45. An article of manufacture as defined in claim 36, said barrier layer initially having a substantially straight longitudinal profile prior to use so that longitudinal curving of said dental desensitizing device is required when said dental desensitizing device is placed over a person's teeth. 46. An article of manufacture as defined in claim 36, said barrier layer comprising a customized dental tray. 47. An article of manufacture as defined in claim 36, said desensitizing layer comprising a single coherent mass in the shape of a dental tray comprising a front side wall, a rear side wall, and a trough between said front and roar side walls. 48. An article of manufactured as defined in claim 36, said dental desensitizing agent comprising at least one member selected from potassium nitrate, other potassium salts, citric acid, citrates, strontium chloride, sodium fluoride, or stannous fluoride. 49. An article of manufacture as defined in claim 36, at least a portion of said tooth adhesion agent comprising polyvinyl pyrrolidone. 50. An article of manufacture as defined in claim 36, said desensitizing composition further comprising at least one dental bleaching agent. 51. A kit fix use in desensitizing a person's teeth comprising a plurality of dental desensitizing devices according to claim 36. 52. A method for desensitizing a person's teeth comprising obtaining a dental desensitizing device according to claim 36 and then placing said dental desensitizing device over at least a portion of the person's teeth for a desired time period. 53. A method of manufacturing an article of manufacture comprising a substantially solid and coherent dental desensitizing composition, the method comprising: mixing together a dental desensitizing agent, a tooth adhesion agent and a solvent to form an intermediate flowable composition; and removing at least a portion of said solvent from said intermediate flowable composition so as to form said substantially solid and coherent dental desensitizing composition, said dental desensitizing composition having a tray-like configuration comprising a front side wall, a rear side wall, and a trough between said front and rear side walls. 54. A method or manufacturing an article of manufacture as defined in claim 53, further comprising forming a barrier layer adjacent to said dental desensitizing composition. 55. A method of manufacturing an article of manufacture as defined in claim 54, wherein said barrier layer comprises a dental tray. 56. A method of manufacturing an article of manufacture as defined in claim 55, said method comprising first placing said intermediate flowable composition adjacent to said dental tray prior and then removing at least a portion of said solvent from said intermediate flowable composition to form said substantially solid and coherent dental desensitizing composition. 57. A method of manufacturing an article or manufacture as defined in claim 55, said method comprising first forming said dental desensitizing composition having a tray-like configuration and then placing it inside a trough within said dental tray. 58. A method of manufacturing an article of manufacture as defined in claim 54, said method comprising applying an initially flowable material adjacent to said denial desensitizing composition and allowing the initially flowable material to substantially solidify into a solid barrier layer. 59. A method of manufacturing an article of manufacture as define in claim 54, said method comprising first placing said intermediate flowable composition adjacent to a polymeric sheet comprising said barrier layer, removing at least a portion of said solvent from said intermediate flowable composition to form a substantially solid and coherent dental desensitizing composition, and shaping said dental desensitizing composition and barrier layer into the tray-like configuration. 60. A method of manufacturing art article of manufacture as defined in claim 54, wherein said barrier layer comprises a single layer of a water-resistant polymeric material.
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