AB block copolymers containing poly (vinyl pyrrolidone) units, medical devices, and methods
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C08F-126/10
C08F-126/00
A61K-031/79
A61K-031/74
출원번호
US-0842176
(2004-05-10)
발명자
/ 주소
Benz,Michael Eric
Alkatout,Julie A
Lyu,SuPing
출원인 / 주소
Medtronic, Inc.
대리인 / 주소
Mueting, Raasch &
인용정보
피인용 횟수 :
1인용 특허 :
40
초록
AnB block copolymers, wherein n is at least two, that include A blocks with poly(vinyl pyrrolidone) units and B blocks with urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, as well as medical devices and methods.
대표청구항▼
The invention claimed is: 1. A medical device comprising a surface comprising a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, ami
The invention claimed is: 1. A medical device comprising a surface comprising a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ester groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 20 carbon atoms or more. 2. The medical device of claim 1 wherein the block copolymer is biocompatible. 3. The medical device of claim 2 wherein the biocompatible block polymer substantially maintains its physical properties and function during the time it remains implanted or in contact with body fluids or tissues. 4. A medical device comprising a surface comprising a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ester groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 100 atoms or more. 5. The medical device of claim 4 wherein the long-chain organic polymeric connecting unit comprises 500 atoms or more. 6. The medical device of claim 5 wherein the long-chain organic polymeric connecting unit comprises 1000 atoms or more. 7. A method of modifying a surface of a medical device, the method comprising: preparing a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 20 carbon atoms or more; and applying the AnB copolymer to the surface of the medical device. 8. The method of claim 7 wherein the block copolymer is biocompatible. 9. The method of claim 8 wherein the biocompatible block copolymer substantially maintains its physical properties and function during the time it remains implanted or in contact with body fluids or tissues. 10. A method of modifying a surface of a medical device, the method comprising: preparing a thermoplastic AnB block copolymer, wherein the A block comprises poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 100 atoms or more; and applying the AnB copolymer to the surface of the medical device. 11. The method of claim 10 wherein the long-chain organic polymeric connecting unit comprises 500 atoms or more. 12. The method of claim 11 wherein the long-chain organic polymeric connecting unit comprises 1000 atoms or more. 13. A thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 20 carbon atoms or more. 14. The block copolymer of claim 13 wherein the block copolymer is biocompatible. 15. The block copolymer of claim 14 wherein the biocompatible block copolymer substantially maintains its physical properties and function during the time it remains implanted or in contact with body fluids or tissues. 16. A thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 100 atoms or more. 17. The block copolymer of claim 16 wherein the long-chain organic polymeric connecting unit comprises 500 atoms or more. 18. The block copolymer of claim 17 wherein the long-chain organic polymeric connecting unit comprises 1000 atoms or more. 19. A method of preparing a thermoplastic AnB block copolymer, the method comprising reacting a substantially monofunctional poly(vinyl pyrrolidone) with a functionalized B-block precursor comprising functional groups reactive with the functional groups of the poly(vinyl pyrrolidone) to form the thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 20 carbon atoms or more. 20. A method of preparing a thermoplastic AnB block copolymer, the method comprising reacting a substantially monofunctional poly(vinyl pyrrolidone) with a functionalized B-block precursor comprising functional groups reactive with the functional groups of the poly(vinyl pyrrolidone) to form the thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 100 atoms or more. 21. A method of preparing a thermoplastic AnB block copolymer, the method comprising reacting a substantially monofunctional poly(vinyl pyrrolidone) with functionalized B-block precursor reactants to form the thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 20 carbon atoms or more. 22. A method of preparing a thermoplastic AnB block copolymer, the method comprising reacting a substantially monofunctional poly(vinyl pyrrolidone) with functionalized B-block precursor reactants to form the thermoplastic AnB block copolymer, wherein the A blocks comprise poly(vinyl pyrrolidone) units and the B block is a long-chain organic polymeric connecting unit comprising urethane groups, urea groups, imide groups, amide groups, ether groups, or combinations thereof, wherein n is at least two, and further wherein the long-chain organic polymeric connecting unit comprises 100 atoms or more.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (40)
Benz, Michael Eric; Alkatout, Julie A.; Lyu, SuPing, AnB block copolymers containing poly (vinyl pyrrolidone) units, medical devices, and methods.
Straub Ferdinand (Hockenheim DEX) Schenck Hans-Uwe (Wachenheim DEX) Lang Siegfried (Ludwigshafen DEX) Brode Egon (Frankenthal DEX), Biodegradable vinylpyrrolidone polymers, their manufacture and use.
Karakelle Mutlu (Dayton OH) Karimi Houshang (Kettering OH) Lee Min-Shui (Spring Valley OH) Taller Robert A. (Centerville OH), Elastomeric segmented hydrophilic polyetherurethane based lubricious coatings.
Eckstein Eugene C. (Miami FL) Block Norman L. (Miami FL) Kline Jacob (Coral Gables FL) Pinchuk Leonard (Miami FL), Hydrogel surface of urological prosthesis.
Creasy Walter S. (Bridgewater NJ) Lorenz Donald H. (Basking Ridge NJ) LaCasse Robert G. (North Plainfield NJ) Malagreca Salvatore A. (Staten Island NY), Hydrophilic polymer blend.
Fan You Ling ; Marlin Lawrence ; Bouldin Lisa M. ; Marino Isabel Maria, Lubricious coatings containing polymers with vinyl and carboxylic acid moieties.
Karimi Houshang (Centerville OH) Wells Stanley C. (Centerville OH) Spielvogel David E. (Springboro OH) Karakelle Mutlu (Centerville OH) Taller Robert A. (Centerville OH), Lubricious coatings, medical articles containing same and method for their preparation.
Karimi Houshang (Centerville OH) Karakelle Mutlu (Spring Valley OH) Taller Robert A. (Centerville OH), Method for applying a lubricious coating to an article.
Fan You L. (East Brunswick NJ) Marlin Lawrence (Bridgewater NJ) Bouldin Lisa M. (Cranford NJ) Marino Isabel M. (Somerset NJ), Non-reactive lubicious coating process.
Khan Mohammad A. (Sandy UT) Karakelle Mutlu (Spring Valley OH) Lee Min-Shiu (Spring Valley OH) Taller Robert A. (Centerville OH), Polyurethane-polyvinylpyrrolidone block copolymer and iodine carrier therefrom.
Hostettler Fritz (Lambertville NJ) Rhum David (New York NY) Forman Michael R. (Ramsey CA) Helmus Michael N. (St. Louis Park MN) Ding Ni (Plymouth MN), Process for producing slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel c.
Hostettler Fritz (New York NY) Rhum David (New York NY) Forman Michael R. (New York NY) Helmus Michael N. (New York NY) Ding Ni (New York NY), Process for producing slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel c.
Szabo Miklos Tamas (Pittsburgh PA) Guilbault Lawrence James (McMurray PA) Sherwood Nancy Spicer (Pittsburg PA), Process for the secondary and tertiary recovery of petroleum.
Spinelli Harry J. (Wilington DE) Anton Waifong L. (Claymont DE) Coleman Henry D. (Brooklyn NY), Silicone-containing acrylic star polymers, block copolymers and macromonomers.
Straub Ferdinand (Hockenheim DEX) Lang Siegfried (Ludwigshafen DEX) Roske Eckhard (Ludwigshafen DEX), Vinylpyrrolidone polymers, their preparation, their use in the preparation of plasma substitutes, and the substitutes th.
Matsutani, Hiroshi; Kaji, Makoto; Abe, Koichi; Uchimaru, Yuko, Borazine-based resin, process for its production, borazine-based resin composition, insulating film and method for its formation.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.