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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Safe and effective biofilm inhibitory compounds and health-related uses thereof

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A01N-031/00    A01N-041/02    A01N-041/00    A01P-001/00    A01P-003/00   
미국특허분류(USC) 523/122; 524/156; 524/158; 524/165; 558/020; 558/037; 568/028; 568/074; 424/405; 424/407; 424/408; 424/409; 424/457; 424/484; 424/489
출원번호 US-0405269 (1999-09-23)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Foley Hoag LLP
인용정보 피인용 횟수 : 44  인용 특허 : 24
초록
▼

The present invention provides compounds and materials that reduce the accumulation of microorganisms a surface, by interfering with the attachment of the organisms to the surface. The compounds and materials are thus useful in preventing the formation of biofilms on surfaces in health-related environments. By preventing the formation of biofilms, the compounds formulated according to the present invention can be used in the fabrication of grafts, implants, medical devices in order to prevent infection thereof. The compounds formulated according to the p...

대표
청구항
▼

The invention claimed is: 1. A coating comprising an effective amount of a compound represented by general structure 1: wherein X represents--OH, F, Cl, or Br; Y represents O; Z represents 4-(2-methylpropyl)phenyl, 4-(1,1-dimethylethyl) phenyl, 4-(1,1-dimethylpropyl)phenyl, 4-pentylphenyl, 4-(1-methyl-1-phenylethyl)phenyl, or 4-(1-methylheptyl)phenyl; wherein when the coating is applied to a surface of an article the coating releases the compound and wherein the coating comprises a phenolic resin, silicone polymer, epoxy resin, polyamide resin, viny...

이 특허에 인용된 특허 (24)

  1. Tanaka Kenichi (Tokyo JPX) Nishimura Shinji (Tokyo JPX) Kawada Hiroshi (Tokyo JPX) Yamaguchi Katsuya (Tokyo JPX) Mizumura Yumi (Tokyo JPX) Nomura Chieko (Tokyo JPX). Agricultural or horticultural fungicide. USP1991105057533.
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  7. Lee Clarence C. (Covington GA). Coating medical devices with cationic antibiotics. USP1990014895566.
  8. Kulla James P. (Perrysburg OH) Huff Norman J. (Swanton OH). Coating process for making antimicrobial medical implant device. USP1986084605564.
  9. Messenger Edward T. (Workington GB2) Mather Douglas E. (Whitehaven GB2) Phillips Brinley M. (Whitehaven GB2). Concentrated aqueous surfactant compositions. USP1981014243549.
  10. Sarangapani Shantha. Encrustation and bacterial resistant coatings for medical applications. USP1999035877243.
  11. Sarangapani Shantha (Walpole MA). Encrusting and bacterial resistant coatings for medical applications. USP1994075328954.
  12. Fox ; Jr. Charles L. (New York NY) Modak Shanta M. (River Edge NJ) Sampath Lester A. (Nyack NY). Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same. USP1991055019096.
  13. Darouiche Rabih O.. Medical implant having a durable, resilient and effective antimicrobial coating. USP1998125853745.
  14. Galin Miles A. (115 E. 38th St. New York NY 10016). Medicament coated intraocular lens. USP1980124240163.
  15. Chesterfield Michael P. (Norwalk CT) Reale Mark P. (Trumbull CT). Method and apparatus for calendering and coating/filling sutures. USP1994055312642.
  16. Raad Isaam (Houston TX) Sherertz Robert (Winston-Salem NC). Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and. USP1997115688516.
  17. Mackles Leonard ; Larkin Mary T. ; Jorgensen Lise ; Chavkin Leonard. Non-tacky and quick-drying aqueous-based antiperspirant compositions. USP1998115833963.
  18. Zimmerman Richard C. (392 Gibson Ave. Pacific Grove CA 93950) Alberte Randall S. (4001 N. Ninth St. Arlington VA 22203) Todd James S. (811 Estrella St. Walla ; Walla WA 99362) Crews Phillip (777 Mont. Phenolic acid sulfate esters for prevention of marine biofouling. USP1995015384176.
  19. Zimmerman Richard C. (Pacific Grove CA) Alberte Randall S. (Arlington VA) Todd James S. (Walla Walla WA) Crews Phillip (Santa Cruz CA). Phenolic acid sulfate esters for prevention of marine biofouling. USP1997035607741.
  20. Destryker Elise (Sint-Pieters-Leeuw BEX) Hannecart Etienne (Tervueren BEX). Process for preparing a latex based on polypyrrole and use of this latex to form a conducting film. USP1991115066706.
  21. Mortimer George A. (Pensacola FL) Pelezo Chris A. (Pensacola FL) Richardson John C. (Cantonment FL). Process for preparing dopes from which shaped articles of oxadiazole/N-alkylhydrazide copolymers are obtained. USP1977094046731.
  22. Huang Wu-Nan (Greer SC) Manwill Niles R. (Belton SC) Chen Fung-Bor (Greer SC). Process for producing medical devices having antimicrobial properties. USP1992025089205.
  23. Blount David H. (5450 Lea St. San Diego CA 92105). Process for the production of broken down lignin-cellulose silicate copolymers. USP1981074281110.
  24. Richter Francis L. (Circle Pines MN) Reinhardt Duane J. (Maplewood MN). Sanitizing compositions. USP1995075436008.

이 특허를 인용한 특허 피인용횟수: 44

  1. Cavitt, T. Brian; Faulkner, Rebecca Ann Herrington. Biofilm resistant polymer materials. USP2015079072292.
  2. McMorrow, David; Heaney, Barry; Malone, Anthony; Flanagan, Aiden; O'Connor, Tim. Coated medical devices for abluminal drug delivery. USP2013048431149.
  3. Gregorich, Daniel J.; Sorenson, Shawn; Meyer, Michael P.. Coating for medical device having increased surface area. USP2014128900292.
  4. Zhou, Pu. Coatings for medical devices comprising a therapeutic agent and a metallic material. USP2014088815275.
  5. Atanasoska, Liliana; Warner, Robert W.; Arney, Michael S.; Weber, Jan. Drug eluting medical devices having porous layers. USP2014088815273.
  6. Alt, Eckhard. Drug-releasing stent with ceramic-containing layer. USP2011118066763.
  7. Lavelle, Shay James. Electrically charged medical device. USP2015059033956.
  8. Lavelle, Shay James. Electrically charged medical device. USP2016079381102.
  9. Biltz, Benjamin T.; Baumann, Bryan. Elongate medical device. USP2017099763814.
  10. Radhakrishnan, Rajesh; Schewe, Scott R.; Schoenle, Victor. Endoprosthese. USP2012108287937.
  11. Kuehling, Michael. Endoprosthesis coating. USP2011088002823.
  12. Schoenle, Victor; Schewe, Scott R.; Radhakrishnan, Rajesh. Endoprosthesis coating. USP2012078216632.
  13. Weber, Jan; Atanasoska, Liliana; Zoromski, Michele. Endoprosthesis coating. USP2013058449603.
  14. Edelman, Peter; Robaina, Samuel. Endoprosthesis having a non-fouling surface. USP2016039284409.
  15. Scheuermann, Torsten; Weber, Jan; Xu, Yixin. Endoprosthesis with coatings. USP2011077981150.
  16. Scheuermann, Torsten; Kuehling, Michael; Anand, Umang; Kokate, Jaydeep Y.; Robaina, Samuel. Endoprosthesis with select ceramic morphology. USP2011077976915.
  17. Melander, Christian; Rogers, Steven A.; Huigens, III, Robert W.. Inhibition and dispersion of bacterial biofilms with benzimidazole derivatives. USP2015129221765.
  18. Melander, Christian; Rogers, Steven A.; Huigens, III, Robert W.; Reed, Catherine S.. Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives. USP2013028367713.
  19. Melander, Christian; Rogers, Steven A.; Huigens, III, Robert W.; Reed, Catherine S.. Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives. USP2011037897631.
  20. Melander, Christian; Rogers, Steven A.; Huigens, III, Robert W.; Reed, Catherine S.. Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives. USP2015099145395.
  21. Melander, Christian; Cavanagh, John; Ritchie, David F.; Rogers, Steven A.; Huigens, III, Robert W.; Reed, Catherine S.. Inhibition and dispersion of biofilms in plants with imidazole-triazole derivatives. USP2016059351491.
  22. Melander, Christian; McCall, W. Steve; Su, Zhaoming; Melander, Roberta. Inhibition of bacterial biofilms and microbial growth with imidazole derivatives. USP2017119815794.
  23. Melander, Christian; McCall, W. Steve; Su, Zhaoming; Melander, Roberta. Inhibition of bacterial biofilms and microbial growth with imidazole derivatives. USP2016039295257.
  24. Melander, Christian; Cavanagh, John; Huigens, III, Robert W.; Ballard, T. Eric; Richards, Justin J.. Inhibition of bacterial biofilms with imidazole derivatives. USP2014028653124.
  25. Melander, Christian; Cavanagh, John; Huigens, III, Robert W.; Ballard, T. Eric; Richards, Justin J.. Inhibition of bacterial biofilms with imidazole derivatives. USP2015079084423.
  26. Melander, Christian; Richards, Justin J.; Bunders, Cynthia. Inhibition of bacterial biofilms with imidazole-phenyl derivatives. USP2015049005643.
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  28. Melander, Christian; Cavanagh, John; Ritchie, David; Huigens, III, Robert W.; Ballard, T. Eric; Richards, Justin J.; Lindsey, Thomas W.; Lindsey, Jonathan S.. Inhibition of biofilms in plants with imidazole derivatives. USP2015018927029.
  29. Melander, Christian; Cavanagh, John; Ritchie, David; Huigens, III, Robert W.; Ballard, T. Eric; Richards, Justin J.; Lindsey, Thomas W.; Lindsey, Jonathan S.. Inhibition of biofilms in plants with imidazole derivatives. USP2012108278340.
  30. Melander, Christian; Cavanagh, John; Ritchie, David; Huigens, III, Robert W.; Ballard, T. Eric; Richards, Justin J.; Lindsey, Thomas W.; Lindsey, Jonathan S.. Inhibition of biofilms in plants with imidazole derivatives. USP2013128618149.
  31. McAlister, Roy E.. Internally reinforced structural composites and associated methods of manufacturing. USP2017069683299.
  32. Flanagan, Aiden; O'Connor, Tim. Medical device coating by laser cladding. USP2012078221822.
  33. Kutryk, Michael J. B.; Cottone, Jr., Robert J.; Rowland, Stephen M.. Medical device with coating for capturing genetically-altered cells and methods for using same. USP2016129522217.
  34. Chandrasekaran, Chandru; Radhakrishnan, Rajesh. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents. USP2012058187620.
  35. Flanagan, Aiden; Kilcooley, John; O'Connor, Tim; O'Brien, Barry; Seidel, Dominique; Kuehling, Michael; Scheuermann, Torsten; Weber, Jan. Medical devices having a coating of inorganic material. USP2014128920491.
  36. Kuehling, Michael; Seidel, Dominique; Scheuermann, Torsten; Weber, Jan. Medical devices having inorganic particle layers. USP2015018932346.
  37. Tenney, Barron; Xu, Yixin; Helmus, Michael N.. Medical devices having nanoporous coatings for controlled therapeutic agent delivery. USP2013118574615.
  38. Weber, Jan; Miller, Matthew. Medical devices with drug-eluting coating. USP2013018353949.
  39. Weber, Jan; Atanasoska, Liliana; Shippy, III, James Lee; Parsonage, Edward E.. Medical devices with selective titanium oxide coatings. USP2014078771343.
  40. Atanasoska, Liliana; Gupta, Pankaj; Deng, Charles. Medical implants including iridium oxide. USP2012078231980.
  41. Cottone, Jr., Robert John; Yoklavich, Margaret; Parker, Sherry. Progenitor endothelial cell capturing with a drug eluting implantable medical device. USP2012018088060.
  42. Holman, Thomas J.; Atanasoska, Liliana. Stent with embedded material. USP2011108029554.
  43. Weber, Jan. Stents with ceramic drug reservoir layer and methods of making and using the same. USP2011118067054.
  44. Rutter, Michael John. Tracheostomy tube. USP2013118573218.

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