Process for controlling the fatty acid chain composition of triglycerides and use thereof
IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0699201
(2003-10-31)
|
우선권정보 |
FI-20021947(2002-11-01) |
발명자
/ 주소 |
- Spars첩,Flemming Vang
- Engelrud,Ulrik
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
8 인용 특허 :
3 |
초록
▼
The present invention relates to a process for controlling the fatty acid chain composition of triglycerides wherein a feed stream comprises a mixture of triglycerides containing at least one long chain. Said mixture is substantially free of trishort chain triglycerides and it is treated in at leas
The present invention relates to a process for controlling the fatty acid chain composition of triglycerides wherein a feed stream comprises a mixture of triglycerides containing at least one long chain. Said mixture is substantially free of trishort chain triglycerides and it is treated in at least two fractionation steps to fractionate between long chain triglycerides at temperatures above 200째 C. and pressures between 0.01 and 10 Pa, wherein one of said steps fractionates between trilong chain triglycerides and mono-and dilong chain triglycerides and the other one of said steps fractionates between monolong chain triglycerides and dilong chain triglycerides. The process can be used for the providing of target triglycerides having a controlled fatty acid chain distribution.
대표청구항
▼
What is claimed is: 1. A process for controlling the fatty acid chain composition of triglycerides wherein a feed stream comprising a mixture of triglycerides containing at least one long fatty acid chain, said mixture being substantially free of trishort chain triglycerides, is treated in at least
What is claimed is: 1. A process for controlling the fatty acid chain composition of triglycerides wherein a feed stream comprising a mixture of triglycerides containing at least one long fatty acid chain, said mixture being substantially free of trishort chain triglycerides, is treated in at least two fractionation steps to fractionate between long chain triglycerides at temperatures above 200째 C. and pressures between 0.01 and 10 Pa, wherein one of said steps fractionates between trilong chain triglycerides and mono-and dilong chain triglycerides and the other one of said steps fractionates between monolong chain triglycerides and dilong chain triglycerides. 2. The process according to claim 1 wherein at least one of the said fractionation steps is performed at a temperature above 270째 C. 3. The process according to claim 1 wherein at least one of said fractionation steps is performed in a fractionation means, wherein the fractionation means is selected from the groups consisting of a distillation unit, a short path distillation column, a centrifugal still and a high vacuum wiped film evaporator. 4. The process of claim 3, wherein the at least one of said fractionation steps is performed in a short path distillation column. 5. The process according to claim 3 wherein said fractionation steps are performed in one or in two or more separate short path distillation columns. 6. The process according to claim 5, wherein a fluid from one of said columns is treated in another fractionation means at a temperature above 200째 C. 7. The process according to claim 1 wherein the triglyceride mixture comprising the feed stream derives from an interesterification of trishort, trimedium and/or trilong chain triglycerides containing the desired fatty acid chains of the desired end product triglyceride. 8. The process according to claim 1 wherein the feed stream has been stripped of trishort chain triglycerides in a stripping column to remove trishort chain triglycerides from said triglycerides before said fractionation steps. 9. The process according to claim 8 wherein the stripped trishort chain triglycerides comprise about 5-40% of the triglycerides before stripping. 10. The process according to claim 9, wherein the stripped trishort chain triglycerides comprises about 10-30% of the triglycerides before stripping. 11. The process according to claim 1 wherein the triglycerides comprising the feed stream derive from an enzymatic techniques using short and/or long fatty acid chain compounds containing the desired fatty acid chains of the desired end product triglyceride. 12. The process according to claim 1 wherein trishort chain stripping is performed after said fractionation steps, with water vapour, at a temperature of about 180-250째 C. and at a pressure of about 10-2000 Pa. 13. The process according to claim 1 wherein both monolong and dilong chain triglycerides are distilled in a first fractionation step at temperatures above 270째 C. to provide a fractionation from trilong chain triglycerides. 14. The process according to claim 13 wherein the distillate from said first fractionation step containing both mono-and dilong chain triglycerides is supplied to a second fractionation step in order to recover the monolong chain triglycerides as distillate and the dilongs as residue at temperatures from about 210 to 270째 C. 15. The process according to claim 14 wherein the monolong and/or dilong chain triglycerides are purified in a stripping step. 16. The process according to claim 1 wherein the majority of the monolong chain triglycerides are distilled off in a first fractionation step. 17. The process according to claim 16 wherein the monolong chain triglycerides are purified in a further step. 18. The process according to claim 16 wherein the residue from the first fractionation step is processed in a second fractionation step at a temperature above 270째 C., and at a pressure of about 0.01-10 Pa, in order to recover the dilong chain triglycerides. 19. The process according to claim 18 wherein the dilong chain triglyceride content of the distillate after the fractionation is more than 50%, with the rest being monolong and trilong chain triglycerides. 20. The process according to claim 19 wherein the dilong chain triglyceride content of the distillate after the fractionation is more than 75%, with the rest being monolong and trilong chain triglycerides. 21. The process according to claim 19 wherein the dilong chain triglyceride content of the distillate after the fractionation is more than 90% with the rest being monolong and trilong chain triglycerides. 22. The process according to claim 18 wherein the distillate from the second fractionation step is supplied to a stripping step in order to purify the dilong chain triglycerides. 23. The process according to claim 1 wherein the feed stream to the distillation column fractionation step is obtained from enzymatic or chemical processes. 24. The process according to claim 1 wherein a third long chain triglyceride fractionation is performed in order to obtain a purer product. 25. The process according to claim 1 wherein the purity of the monolong and/or dilong chain triglyceride product is at least about 75%. 26. The process according to claim 25, wherein the purity of the monolong and/or dilong chain triglyceride product is at least about 90%. 27. The process according to claim 25, wherein purity of the monolong and/or dilong chain triglyceride product is at least about 95%. 28. The process according to claim 1 wherein the long chain fatty acids in the triglyceride contain from 12 to 24 carbon atoms and are selected from the group consisting of lauric, myristic, palmitic, stearic, arachidic, behenic, lignoceric, palmitoleic, oleic, gadoleic, arachidonic, linoleic, α-linolenic acids and, DHA and EPA. 29. The process according to claim 1 wherein the short chain fatty acids in the triglyceride contain from 2 to 4 carbon atoms and are selected from the group consisting of acetic, propionic and butyric acid. 30. A method of using the process according to claim 1 for the providing of target triglycerides having a controlled fatty acid chain distribution and composition, said use comprising the steps of defining at least one target long chain fatty acid of the target triglyceride(s); optionally defining the target position(s) of said long chain fatty acid(s); providing a triglyceride starting material containing a significant amount of the target triglyceride(s) having a desired fatty acid chain distribution; at need, removing trishort chain triglycerides from said starting material to provide a feed stream substantially free of trishort chain triglycerides; treating said feed stream in at least two fractionation steps at temperatures above 200째 C. and pressures between 0.01 and 10 Pa in order to fractionate between the long chain triglycerides; and recovering the target triglyceride(s) containing at least one of said target long chain fatty acid(s) having the desired fatty acid chain distribution. 31. The method according to claim 30 wherein the target triglyceride(s) is/are recovered at a purity above 75%. 32. The method according to claim 30 wherein the target triglyceride(s) is/are recovered at a purity above 90%.
이 특허에 인용된 특허 (3)
-
Bell Stacey J. ; Forse R. Armour ; Bistrian Bruce R., Nutritional supplement for preoperative feeding.
-
Cherwin Daniel Eric ; Johnson ; Jr. James William, Process for making low calorie triglycerides having long and short fatty acid chains.
-
Casimir C. Akoh, Structured lipids.
이 특허를 인용한 특허 (8)
-
Casolari, Jason; Rudenko, George N.; Franklin, Scott; Zhao, Xinhua, Acyl-ACP thioesterases and mutants thereof.
-
Shinde, Sandip; Kale, Aniket; Kulaga, Tom; Licamele, Jason D.; Tonkovich, Anna Lee, Omega 7 rich compositions and methods of isolating omega 7 fatty acids.
-
Rudenko, George N.; Casolari, Jason; Franklin, Scott, Thioesterases and cells for production of tailored oils.
-
Rudenko, George N.; Casolari, Jason; Franklin, Scott, Thioesterases and cells for production of tailored oils.
-
Davis, David, Variant thioesterases and methods of use.
-
Davis, David, Variant thioesterases and methods of use.
-
Davis, David; Franklin, Scott; Moseley, Jeffrey L.; Bhat, Riyaz, Variant thioesterases and methods of use.
-
Davis, David; Franklin, Scott; Moseley, Jeffrey L.; Bhat, Riyaz, Variant thioesterases and methods of use.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.