초록 ▼

A device, system and method for enhancing the functionality and efficiency of a chemical and/or enzymatic debriding agent with a physical debriding mechanism. The debriding agent alone and the physical mechanism alone are each capable of at least some debriding activity separately, without being use

A device, system and method for enhancing the functionality and efficiency of a chemical and/or enzymatic debriding agent with a physical debriding mechanism. The debriding agent alone and the physical mechanism alone are each capable of at least some debriding activity separately, without being used in the combination. In combination, however, they are more effective, such that the debriding efficacy is increased for the combination. Preferably, the physical debriding mechanism comprises an ultrasound source.

대표청구항 ▼

What is claimed is: 1. A system for debridement of an area of eschar, comprising: (a) a device comprising an ultrasound source for delivering ultrasound radiation having a debriding effect on eschar, a spacer for maintaining the ultrasound source at a distance from the area of eschar and a containe

What is claimed is: 1. A system for debridement of an area of eschar, comprising: (a) a device comprising an ultrasound source for delivering ultrasound radiation having a debriding effect on eschar, a spacer for maintaining the ultrasound source at a distance from the area of eschar and a container coupled to the ultrasound source, said container being adapted to be placed over the area of eschar, said container containing an acoustic medium for enabling the area of eschar to be exposed to ultrasonic radiation from said ultrasound source; and (b) a debriding composition for use in combination with said ultrasonic radiation and being in contact at least temporarily with said area of eschar, wherein the debriding composition comprises at least one enzymatic debriding agent. 2. The system of claim 1, wherein said acoustic medium includes said debriding composition. 3. The system of claim 2, wherein said container further comprises an opening for enabling said debriding composition to contact said area of skin to be debrided. 4. The system of claim 3, wherein said container further comprises a peripheral seal for sealing said opening against said area of skin to be debrided. 5. The system of claim 3, further comprising an inlet in said container for inserting said debriding composition. 6. The system of claim 5, further comprising an outlet in said container for removing said debriding composition. 7. The system of claim 5, further comprising an outlet in said container for creating a vacuum for sealing said opening against said area of skin. 8. The system of claim 1, wherein said container further comprises an opening for being placed against said area of skin to be debrided, and also further comprises an inlet, such that said debriding composition may be inserted into said container before, during or after treatment with said ultrasonic radiation. 9. The system of claim 8, wherein said container further comprises an outlet for removing at least one of said acoustic medium and said debriding composition. 10. The system of claim 8, wherein said container further comprises a peripheral seal for sealing said opening against said area of skin to be debrided. 11. The system of claim 1, wherein said ultrasound source comprises a piezoelectric ultrasound source unit. 12. The system of claim 1, wherein said spacer is combined with said container. 13. The system of claim 1, wherein said debriding composition further comprises at least one chemical agent. 14. The system of claim 1, wherein said debriding composition further comprises at least one of a liquid and a semi-solid carrier. 15. The system of claim 1, wherein said debriding composition further comprises a stabilizer. 16. The system of claim 1, wherein said debriding composition comprises a vegetable preparation. 17. The system of claim 16, wherein said vegetable preparation comprises a bromelain derivative. 18. The system of claim 17, wherein said bromelain derivative comprises Debridase. 19. A method for debridement of an area of dead skin tissue comprising: contacting the area of dead skin tissue with a debriding composition, the debriding composition comprising at least one enzymatic debriding agent; and applying ultrasonic radiation having a debriding effect on dead skin tissue to the area of dead skin tissue; wherein said contacting and said applying are performed in any order and said ultrasonic radiation enhances debridement of the dead skin tissue by the debriding composition. 20. The method of claim 19, wherein said applying and said contacting are performed concurrently. 21. The method of claim 19, wherein said applying is performed before said contacting. 22. The method of claim 19, wherein said contacting is performed before said applying. 23. The method of claim 19, wherein said debriding composition further comprises at least one chemical debriding agent. 24. The method of claim 19, wherein said debriding composition further comprises at least one of a liquid and a semi-solid carrier. 25. The method of claim 19, wherein said debriding composition further comprises a stabilizer. 26. The method of claim 19, wherein said debriding composition comprises a vegetable preparation. 27. The method of claim 26, wherein said vegetable preparation comprises a bromelain derivative. 28. The method of claim 27, wherein said bromelain derivative comprises Debridase. 29. A system for debridement of dead skin tissue, comprising: (a) a device comprising an ultrasound source for delivering ultrasound radiation having a debriding effect on dead skin tissue, a spacer for maintaining the ultrasound source at a distance from the area of dead skin tissue and an acoustic medium for enabling the area of dead skin tissue to be exposed to ultrasonic radiation from the ultrasound source, wherein said ultrasound source is placed in contact with said acoustic medium manually; and (b) a debriding composition for use in combination with said ultrasonic radiation and being in contact, at least temporarily, with the area of dead skin tissue, wherein the debriding composition comprises at least one enzymatic debriding agent. 30. The system of claim 29, wherein said acoustic medium includes said debriding composition. 31. The system of claim 29, wherein said debriding composition further comprises at least one chemical debriding agent. 32. The system of claim 29, wherein said debriding composition further comprises at least one of a liquid and a semi-solid carrier. 33. The system of claim 32, wherein said debriding composition further comprises a stabilizer. 34. The system of claim 29, wherein said debriding composition comprises a vegetable preparation. 35. The system of claim 34, wherein said vegetable preparation comprises a bromelain derivative. 36. The system of claim 35, wherein said bromelain derivative comprises Debridase.