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Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/44
출원번호 US-0154857 (2002-05-24)
발명자 / 주소
  • Lotz,Jeffrey C.
  • Colliou,Olivier K.
  • Bradford,David S.
출원인 / 주소
  • The Regents of the University of California
인용정보 피인용 횟수 : 72  인용 특허 : 75

초록

A bioactive/biodegradable nucleus implant for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant is inflated with a high molecular weight fl

대표청구항

What is claimed is: 1. An implant for repairing an intervertebral disc, which disc comprises an annulus that substantially surrounds a nuclear space and is located between first and second adjacent vertebrae, said implant comprising: an inflatable membrane; said membrane having an internal chamber;

이 특허에 인용된 특허 (75)

  1. Felt Jeffrey C. ; Bourgeault Craig A. ; Baker Matthew W., Articulating joint repair.
  2. Felt Jeffrey C. ; Bourgeault Craig A. ; Baker Matthew W., Articulating joint repair.
  3. Oka Masanori (Nara JPX) Gen Shokyu (Uji JPX) Ikada Yoshito (Uji JPX) Okimatsu Hideaki (Kyoto JPX), Artificial bone connection prosthesis.
  4. Brosnahan Robert ; Small Laura A. ; Bearcroft Julie A., Artificial bone graft implant.
  5. Oka Masanori (Nara JPX) Gen Shokyu (Uji JPX) Ikada Yoshito (Uji JPX) Okimatsu Hideaki (Kyoto JPX), Artificial intervertebral disc.
  6. Patil Arun A. (1011 Valley View Dr. Minot ND 58701), Artificial intervertebral disc.
  7. Kuras James M. ; DiNello Alexandre M. ; McMillin Carl R., Artificial spinal disc.
  8. Michelson Gary K. (Venice CA), Artificial spinal fusion implants.
  9. Felt Jeffrey C. ; Rydell Mark A. ; Zdrahala Richard J. ; Arsenyev Alexander, Biomaterial for in situ tissue repair.
  10. Felt Jeffrey C. ; Rydell Mark A. ; Zdrahala Richard J. ; Arsenyev Alexander, Biomaterial system for in situ tissue repair.
  11. Eaton L. Daniel (Little Rock AR), Breast prosthesis.
  12. Pekar Robert W. (Florence MA), Check valve for fluid bladders.
  13. Lewis W. Fleischmann ; Christopher Galuardi, Collapsible, rotatable and expandable spinal hydraulic prosthetic device.
  14. Gan Jean Chin Chin ; Ducheyne Paul ; Vresilovic Edward ; Shapiro Irving, Compositions and methods for intervertebral disc reformation.
  15. Hoi S. (La Jolla CA), Detachable balloon catheter.
  16. Pecenka Frank (Miami Beach FL), Detachable balloon catheter.
  17. Strother Charles M. (Madison WI) Kudva Balakrishna V. (Monona WI), Detachable balloon catheter.
  18. Makita Kohzoh (Tokyo JPX) Machida Tohru (Tokyo JPX), Detachable balloon with two self-sealing valves.
  19. Haynes Darrel W. (3804 Offutt Rd. Randallstown MD 21133), Device and method for plugging an intramedullary bone canal.
  20. Krapiva Pavel I. (10008 Edward Ave. Bethesda MD 20814), Disc replacement method and apparatus.
  21. Dormandy ; Jr. Ray H., Dual valve detachable occlusion balloon and over-the-wire delivery apparatus and method for use therewith.
  22. Kuslich Stephen D. (2400 Keller Pkwy. Maplewood MN 55109), Expandable fabric implant for stabilizing the spinal motion segment.
  23. Kuslich Stephen D. (2400 Keller Pkwy. Maplewood MN 55109), Expandable fabric implant for stabilizing the spinal motion segment.
  24. Foley Kevin ; Ebner Harald,DEX ; Liu Mingyan,FRX ; Branch Charles ; Boyd Lawrence M., Expandable intervertebral spacers.
  25. Lee Casey K. (Short Hills NJ) Langrana Noshir A. (Robbinsville NJ) Alexander Harold (Short Hills NJ) Clemow Alastair J. (Princeton NJ) Chen Elizabeth H. (Princeton NJ) Parsons John R. (Perth Amboy NJ, Functional and biocompatible intervertebral disc spacer.
  26. Parsons John R. (Perth Amboy NJ) Lee Casey K. (Short Hills NJ) Langrana Noshir A. (Robbinsville NJ) Clemow Alastair J. (North Smithfield RI) Chen Elizabeth H. (Sharon MA) Hawkins Monica V. (Parsippan, Functional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness.
  27. Parsons John R. (Perth Amboy NJ) Lee Casey K. (Short Hills NJ) Langrana Noshir A. (Robbinsville NJ) Clemow Alastair J. (Princeton NJ) Chen Elizabeth H. (Princeton NJ), Functional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness.
  28. Hamas Robert S. (Woodhill Medical Park ; 8345 Walnut Hill La. ; Suite 120 Dallas TX 75231), Gel-like prosthetic device.
  29. Bryan Vincent (Mercer Island WA) Kunzler Alex (Bellevue WA), Human spinal disc prosthesis.
  30. Bryan Vincent ; Kunzler Alex, Human spinal disc prosthesis.
  31. Bao Qi-Bin (Livingston NJ) Higham Paul A. (Ringwood NJ), Hydrogel bead intervertebral disc nucleus.
  32. Bao Qi-Bin (Livingston NJ) Higham Paul A. (Ringwood NJ), Hydrogel intervertebral disc nucleus.
  33. Bao Qi-Bin ; Higham Paul A., Hydrogel intervertebral disc nucleus.
  34. Bao Qi-Bin (New York NY) Higham Paul A. (New York NY), Hydrogel intervertebral disc nucleus with diminished lateral bulging.
  35. Becker Hilton (301 Dunbar Rd. Palm Beach FL 33408), Implant and inflating construction.
  36. Bruce, Lars; Bruce, Ingrid, Implant, method of making the same and use the same.
  37. Ravo Biagio (220 Weatherill Rd. Garden City NY 11530), Implantable reservoir adapted to receive and store structural devices therein.
  38. Bao Qi-Bin ; Yuan Hansen A., Implantable tissue repair device.
  39. Ducheyne Paul ; Radin Shulamith ; Santos Erick Manuel, Incorporation of biologically active molecules into bioactive glasses.
  40. Douglas Wardlaw GB, Intervertebral disc nucleus prosthesis.
  41. Kuntz J. David (899 Lahakas Blvd. Kitimat ; B.C. CAX), Intervertebral disc prosthesis.
  42. Baumgartner Walter (Wil CHX), Intervertebral prosthesis.
  43. Husson Jean-Louis,FRX ; Baumgartner Walter,CHX ; Freudiger Stefan,CHX, Intervertebral prosthesis.
  44. Baumgartner Walter,CHX, Intervertebral prosthesis and a process for implanting such a prosthesis.
  45. Gau Fred C. (14812 Imperial Dr. Libertyville IL 60048) Hancock John C. (449 Paseo del Descanso Santa Barbara CA 93105), Intragastric balloon with improved valve locating means.
  46. Frey Otto (Winterthur CHX) Koch Rudolf (Berlingen CHX) Planck Heinrich M. F. (Nurtigen DEX), Joint endoprosthesis.
  47. Felt Jeffrey C., Joint resurfacing system.
  48. Felt Jeffrey C. (Greenwood MN), Joint resurfacing system.
  49. Georgiade Nicholas G. (Durham NC), Mammary prosthesis fill and method of making same.
  50. Sharkey Hugh R. ; Ashley John ; Saal Joel ; Saal Jeffrey A. ; Le Le Trong, Method and apparatus for delivering or removing material from the interior of an intervertebral disc.
  51. Bao Qi-Bin ; Higham Paul A. ; Bagga Charanpreet S. ; Yuan Hansen A., Method and apparatus for injecting an elastic spinal implant.
  52. Reuter, Merrill W.; Reuter, Gerald L.; Rehder, Carey D., Method and device for treating intervertebral disc herniations.
  53. Stone Kevin R. (San Francisco CA), Method for making a prosthetic intervertebral disc.
  54. Sharkey Hugh J. ; Ashley John ; Saal Joel ; Saal Jeffrey ; Le Le Trong, Method for manipulating tissue of an intervertebral disc.
  55. Ray Charles D. (Golden Valley MN) Dickhudt Eugene A. (New Brighton MN), Method for surgical implantation of a prosthetic spinal disc nucleus.
  56. Sharkey Hugh R. ; Saal Joel ; Saal Jeffrey A. ; Ashley John, Method for treating intervertebral disc degeneration.
  57. Petrick Timothy B. (9006 Trinity Gardens North Brooklyn Park MN 55443), Method of inflating a prosthesis.
  58. Jeffrey C. Felt ; Mark A. Rydell ; Richard J. Zdrahala ; Alexander Arsenyev, Mold apparatus and kit for in situ tissue repair.
  59. Assell Robert L. ; Ray Charles D., Percutaneous prosthetic spinal disc nucleus and method of manufacture.
  60. Baumgartner Walter (Wil CHX), Process for implanting an invertebral prosthesis.
  61. Ray Charles D. (Deephaven MN) Corbin Terry P. (Golden Valley MN), Prosthetic disc and method of implanting.
  62. Ray Charles D. (Wayzata MN) Corbin Terry P. (Golden Valley MN), Prosthetic disc containing therapeutic material.
  63. Stone Kevin R. (San Francisco CA), Prosthetic intervertebral disc.
  64. Ray Charles D. (Golden Valley MN) Dickhudt Eugene A. (New Brighton MN) Ledoux Philip J. (Stillwater MN) Frutiger Beth A. (Minneapolis MN), Prosthetic spinal disc nucleus.
  65. Ray Charles D. ; Dickhudt Eugene A. ; Assell Robert L., Prosthetic spinal disc nucleus.
  66. Steffee Arthur D. ; Ross E. Raymond,GBX ; Fraser Robert D.,AUX ; Lowery Gary L., Spinal disc.
  67. Kenna Robert V. (Hobe Sound FL), Spinal implant.
  68. Navarro Richard R. (Strongsville OH) McMillin Carl R. (Brecksville OH) Zimmers Karl B. (Ravenna OH), Spine disc.
  69. Rydell Mark A., Static mixer.
  70. McLeod Alan Rory Mor,GBX ; Jackowski Andre,GBX, Surgical implant.
  71. Scholten Arie (4175 Tamayo St. Fremont CA 94536) Reiley Mark A. (333 63rd St. Oakland CA 94618), Surgical protocol for fixation of bone using inflatable device.
  72. Bark Jeffrey E. (Paso Robles CA) Falk John E. (Racine WI), Tissue expander.
  73. Ray Charles D. ; Assell Robert L., Trial implant and trial implant kit for evaluating an intradiscal space.
  74. Main John A. (Nashville TN) Wells Mark E. (Huntsville AL) Keller Tony S. (Nashville TN), Vertebral prosthesis.
  75. Chu Chia-Hui,TWX, Water bag type brassiere padding with a valve.

이 특허를 인용한 특허 (72)

  1. Boyan, Barbara D.; Kennedy, Stephen J.; Schwartz, Zvi, Articular joint implant.
  2. Gerber, David; Coppes, Justin K.; Angelucci, Christopher; Paul, David C.; Stihl, Pascal; Boyer, Michael L., Artificial intervertebral disc implant.
  3. Ainsworth, Stephen D.; Assell, Robert L.; Cragg, Andrew H.; Wessman, Bradley J., Assemblies for provision of therapy to motion segments.
  4. Vanleeuwen, Ryan; Vaughn, Shannon; Weisel, Thomas, Balloon implant device.
  5. Vanleeuwen, Ryan; Vaughn, Shannon; Weisel, Thomas, Balloon implant device.
  6. Zucherman,James F.; Hsu,Ken Y., Bioresorbable interspinous process implant for use with intervertebral disk remediation or replacement implants and procedures.
  7. McCormack, Bruce M.; Liou, Edward; Smith, Jeffrey D.; Schummers, David Michael, Cage spinal implant.
  8. McCormack, Bruce M.; Liou, Edward; Smith, Jeffrey D.; Schneider, Scott, Cervical cage.
  9. McCormack, Bruce, Cervical distraction method.
  10. McCormack, Bruce M., Cervical distraction method.
  11. McCormack, Bruce M., Cervical distraction method.
  12. McCormack, Bruce M., Cervical distraction method.
  13. McCormack, Bruce M.; Smith, Jeffrey D., Cervical distraction/implant delivery device.
  14. McCormack, Bruce M.; Smith, Jeffrey D., Cervical distraction/implant delivery device.
  15. McCormack, Bruce M.; Liou, Edward; Schummers, David Michael; Smith, Jeffrey D., Composite spinal facet implant with textured surfaces.
  16. McCormack, Bruce M.; Liou, Edward; Schummers, David Michael; Smith, Jeffrey D., Composite spinal facet implant with textured surfaces.
  17. Gerber, David; Coppes, Justin K.; Angelucci, Christopher; Paul, David C.; Stihl, Pascal; Boyer, Michael L., Controlled artificial intervertebral disc implant.
  18. Ainsworth, Stephen D.; Arthurs, Brandon B.; Assell, Robert L.; Dickhudt, Eugene A.; Wessman, Bradley J., Drivers for inserts to bone anchors.
  19. McCormack, Bruce M.; Smith, Jeffrey D., Facet joint implants and delivery tools.
  20. McCormack, Bruce M.; Smith, Jeffrey D., Facet joint implants and delivery tools.
  21. Gong, Glen; Pai, Suresh Subraya; Sershen, Scott Robert, Fragmented hydrogels.
  22. Karwa, Anupama; Ganpath, Raj P.; Colton, Clark K.; Rao, K. T. Venkateswara, Graft systems having semi-permeable filling structures and methods for their use.
  23. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  24. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  25. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  26. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  27. Boyan, Barbara D.; Guldberg, Robert E.; Kennedy, Stephen J.; Ku, David N.; Schwartz, Zvi, Hydrogel implant with superficial pores.
  28. Patrick, Timothy J.; Ramey, Carribeth B.; Tudor, Letitia; Axelrod, Michael A., Hydrogel implants with porous materials and methods.
  29. Park, Kee B., Inflatable disk implant.
  30. Eckman, Walter W., Insertion tool for a vertebral defect device.
  31. Coppes, Justin K.; Gerber, David; Paul, David C.; Lee, Andrew, Intervertebral disc implant.
  32. Lechmann, Beat; Frigg, Robert; Buerki, Roger, Intervertebral prosthesis or disk prosthesis.
  33. Lechmann, Beat; Frigg, Robert; Buerki, Roger, Intervertebral prosthesis or disk prosthesis.
  34. Lechmann, Beat; Frigg, Robert; Buerki, Roger, Intervertebral prosthesis or disk prosthesis.
  35. Lechmann, Beat; Frigg, Robert; Buerki, Roger, Intervertebral prosthesis or disk prosthesis.
  36. McCormack, Bruce M.; Liou, Edward; Tanaka, Shigeru; Phan, Christopher U., Lateral mass fixation system.
  37. Steinberg, Amiram, Method and apparatus for computerized surgery.
  38. Boyan, Barbara D.; Kennedy, Stephen J., Method of making hydrogel implants.
  39. Boyan, Barbara D.; Guldberg, Robert E.; Kennedy, Stephen J.; Ku, David N., Method of making load bearing hydrogel implants.
  40. Boyan, Barbara D.; Kennedy, Stephen J.; Schwartz, Zvi, Method of treating joints with hydrogel implants.
  41. Ainsworth, Stephen D.; Assell, Robert L.; Cragg, Andrew H.; Dickhudt, Eugene A.; Schwarz, Tawney A.; Wessman, Bradley J., Methods and apparatus for provision of therapy to adjacent motion segments.
  42. Ainsworth, Stephen D.; Assell, Robert L.; Cragg, Andrew H.; Wessman, Bradley, Methods for push distraction and for provision of therapy to adjacent motion segments.
  43. Walsh, Steven P.; Tudor, Letitia; Corrao, Ernest N.; Berky, Craig B.; Bauer, Jonathan P.; Hemingway, Jeremy; Axelrod, Michael, Methods of repairing a joint using a wedge-shaped implant.
  44. Perez-Cruet, Miquelangelo J.; Pepper, John R.; Miller, John A., Minimally invasive interbody device.
  45. Milijasevic, Zoran; Diwan, Ashish, Minimally invasive tissue prosthesis implanting device and method.
  46. Ainsworth, Stephen D.; Arthurs, Brandon B.; Assell, Robert L.; Wessman, Bradley J., Multi-membrane prosthetic nucleus.
  47. Gong, Glen; Pai, Suresh Subraya; Sershen, Scott Robert, Polysaccharide based hydrogels.
  48. Oi, Nelson; Companioni, Wilder; May, Jason Michael; West, Michael V.; White, Stephen Edward, Port structures for non-rigid bone plates.
  49. Cragg, Andrew H.; Assell, Robert L.; Ainsworth, Steven D.; Dickhudt, Eugene A.; Wessman, Bradley J., Prosthetic nucleus apparatus.
  50. Ainsworth, Stephen D.; Wessman, Bradley J., Prosthetic nucleus with a preformed membrane.
  51. Hibri, Nadi Salah; Lutz, James Douglas, Prosthetic spinal disk nucleus.
  52. Kuslich, Stephen D., Semi-biological intervertebral disc replacement system.
  53. McCormack, Bruce M.; Liou, Edward; Schummers, David Michael; Smith, Jeffrey D., Spinal facet cage implant.
  54. McCormack, Bruce M.; Liou, Edward; Schummers, David Michael; Smith, Jeffrey D., Spinal facet cage implant.
  55. McCormack, Bruce M.; Liou, Edward; Smith, Jeffrey D., Spinal implant.
  56. Cragg, Andrew H.; Assell, Robert L.; Ainsworth, Steven D.; Dickhudt, Eugene A.; Wessman, Bradley J., Spinal mobility preservation apparatus.
  57. Ainsworth, Stephen D.; Arthurs, Brandon B.; Assell, Robert L.; Dickhudt, Eugene A.; Wessman, Bradley J., Spinal motion preservation assemblies.
  58. Ainsworth, Stephen D.; Assell, Robert L.; Dickhudt, Eugene A.; Wessman, Bradley J., Spinal motion preservation assemblies.
  59. Boyan, Barbara D.; Kennedy, Stephen J.; Schwartz, Zvi, Surface directed cellular attachment.
  60. Walsh, Steven P.; Tudor, Letitia; Corrao, Jr., Ernest N.; Berky, Craig B.; Bauer, Jonathan P.; Hemingway, Jeremy, Tapered joint implant and related tools.
  61. Ainsworth, Stephen D.; Wessman, Bradley J., Therapy to adjacent motion segments.
  62. Eckman, Walter W., Vertebral defect device.
  63. Eckman,Walter W., Vertebral defect device.
  64. McCormack, Bruce M.; Lombrozo, Peter; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin, Vertebral joint implants and delivery tools.
  65. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  66. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  67. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  68. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  69. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  70. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  71. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
  72. McCormack, Bruce M.; Smith, Jeffrey D.; Tanaka, Shigeru; Liou, Edward; Eyster, Edward Fletcher; Carver, Jonathan; Druker, Joshua; Leugers, Martin; Tu, Kurin; Lombrozo, Peter, Vertebral joint implants and delivery tools.
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