초록

Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

대표청구항 ▼

What is claimed is: 1. A catheter system for modifying an annulus of a heart valve to reduce regurgitation of blood flow through the valve, comprising: a catheter having at least one lumen, first and second fasteners adapted to be secured to the annulus, first and second flexible tensile members re

What is claimed is: 1. A catheter system for modifying an annulus of a heart valve to reduce regurgitation of blood flow through the valve, comprising: a catheter having at least one lumen, first and second fasteners adapted to be secured to the annulus, first and second flexible tensile members respectively coupled to said first and second fasteners, and a crimping device deployable through said catheter and including a crimp and a compression applying mechanism configured to compress said crimp onto said first and second flexible tensile members after said fasteners are pulled toward one another with said flexible tensile members to reduce the circumferential length of the annulus, and first and second portions adapted to rotate relative to each other, and wherein said compression applying mechanism is configured to compress said crimp when said first and second portions are rotated. 2. The system of claim 1, further comprising a cutting mechanism associated with said crimping device and configured to cut said first and second flexible tensile members after compression of said crimp. 3. The system of claim 1, further comprising a third fastener adapted to be secured to the annulus and a third flexible tensile member coupled to said third fastener, wherein said third flexible tensile member is threaded through said crimp. 4. The system of claim 1, wherein said first portion threadably engages said second portion. 5. A catheter system for modifying an annulus of a heart valve to reduce regurgitation of blood flow through the valve, comprising: a catheter having at least one lumen, first and second fasteners adapted to be secured to the annulus, first and second separate flexible tensile members respectively coupled to said first and second fasteners, said first and second separate flexible tensile members each having first and second free ends, a locking element delivery device deployable through said catheter and capable of selectively securing said first and second flexible tensile members together with a locking element after said fasteners are pulled toward one another with said flexible tensile members to reduce the circumferential length of the annulus, and a third fastener adapted to be secured to the annulus and a third flexible tensile member coupled to said third fastener, wherein said third flexible tensile member further includes first and second free ends and is capable of being secured to said first and second flexible tensile members by said locking element. 6. The system of claim 5, further comprising a cutting mechanism associated with said locking element delivery device and configured to cut said first, second and third flexible tensile members after said locking element has secured said first, second and third flexible tensile members. 7. The system of claim 5, wherein said locking element delivery device is capable of being actuated to selectively move the locking element into a locked condition after achieving a desired amount of reduction in the circumferential length of the annulus by pulling on said flexible tensile members.