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Microfabricated elastomeric valve and pump systems 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B81B-005/00
출원번호 US-0150895 (2002-05-15)
발명자 / 주소
  • Unger,Marc A.
  • Chou,Hou Pu
  • Thorsen,Todd A.
  • Scherer,Axel
  • Quake,Stephen R.
출원인 / 주소
  • California Institute of Technology
대리인 / 주소
    Townsend and Townsend and Crew LLP
인용정보 피인용 횟수 : 45  인용 특허 : 52

초록

A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a se

대표청구항

What is claimed is: 1. A method of microfabricating an elastomeric structure, comprising: forming a first elastomeric layer on a substrate; curing the first elastomeric layer; patterning a first sacrificial layer over the first elastomeric layer; forming a second elastomeric layer over the first el

이 특허에 인용된 특허 (52)

  1. Sanjoh Akira,JPX, Apparatus for crystal growth and crystal growth method employing the same.
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  6. Yamazaki ; Toru, Elastomer display device.
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  8. Horres ; Jr. Charles R. (Del Mar CA), Electrochemical controlled dispensing assembly and method for selective and controlled delivery of a dispensing fluid.
  9. Cabuz Cleopatra, Electrostatically actuated mesopump having a plurality of elementary cells.
  10. Naruse Yoshihiro (Ichikawa JPX) Ando Mitsuhiro (Tokyo JPX) Mizuno Tomokimi (Ichikawa JPX) Nakajima Naomasa (Tokyo JPX), Fluid flow regulating device.
  11. Parce John Wallace ; Kopf-Sill Anne R. ; Bousse Luc J., High throughput screening assay systems in microscale fluidic devices.
  12. Surjaatmadja Jim B. (Duncan OK), Hydraulic digital stepper actuator.
  13. Quake, Stephen R.; Chou, Hou-Pu, Integrated active flux microfluidic devices and methods.
  14. Lipshutz Robert J. ; Rava Richard P. ; Anderson Rolfe C. ; Fodor Stephen P. A., Integrated nucleic acid diagnostic device.
  15. Unger, Marc A.; Chou, Hou-Pu; Thorsen, Todd A.; Scherer, Axel; Quake, Stephen R., Method of making a microfabricated elastomeric valve.
  16. Feingold Robert M. (Annandale VA), Method of making a plate having a pattern of microchannels.
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  18. Frisch Eldon E. (Midland MI), Methods of forming permeation-resistant, silicone elastomer-containing composite laminates and devices produced thereby.
  19. Young Robert M. (Pittsburgh PA) Freidhoff Carl B. (Murrysville PA), Micro-miniature diaphragm pump for the low pressure pumping of gases.
  20. Zengerle Roland (Mnchen DEX) Richter Axel (Mnchen DEX), Micro-miniaturized, electrostatically driven diaphragm micropump.
  21. Tai Yu-Chong ; Yang Xing, Microbellows actuator.
  22. Faris Sadeg M. (24 Pocantico River Rd. Pleasantville NY 10570) Jain Kanti (18 Algonquian Trail Briarcliff Manor NY 10510), Microchannel plate technology.
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  25. Moles Donald R., Microfluidic analyzer module.
  26. Ekstrm Bjrn (Upsala SEX) Jacobson Gunilla (Upsala SEX) Ohman Ove (Upsala SEX) Sjdin Hakan (Upsala SEX), Microfluidic structure and process for its manufacture.
  27. Kopf-Sill Anne R. ; Parce John Wallace, Microfluidic systems incorporating varied channel dimensions.
  28. Yu-Chong Tai ; Xing Yang ; Charles Grosjean ; Xuan-Qi Wang, Micromachined parylene membrane valve and pump.
  29. Hartley Frank T., Micromachined peristaltic pump.
  30. Hartley Frank T., Micromachined peristaltic pumps.
  31. Huff Michael A. (Medford MA) Schmidt Martin A. (Reading MA), Micromachined threshold pressure switch and method of manufacture.
  32. Richter Axel (Mnchen DEX), Microminiaturized pump.
  33. Van Lintel Harald,CHX, Micropump.
  34. van Lintel Harald (Martigny CHX), Micropump having a constant output.
  35. Kamisuki Shinichi (Suwa JPX) Nose Yasuto (Suwa JPX) Shimizu Nobuo (Suwa JPX) Yotsuya Shinichi (Suwa JPX), Micropump with valve structure.
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  38. Tai, Yu-Chong; Wang, Xuan-Qi, Parylene micro check valve and fabrication method thereof.
  39. Bouteille Daniel (Ville d\Avray FRX) Duclos Michel (Verneuil l\Etang FRX) Marguet Hugues (Paris FRX) Nicolas Michel (Plaisir FRX) Petrimaux Eric (Evreux FRX), Pneumatic logic circuit.
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  44. Trah Hans-Peter (Reutlingen DEX), Thermal micropump with values formed from silicon plates.
  45. Zachary Bryan A. ; Summers Angela E., Two out of three voting solenoid arrangement.
  46. van Lintel Harald T. G. (Enschede NLX), Two valve micropump with improved outlet.
  47. Miyazaki Hajime (Suwa JPX) Handa Masaaki (Suwa JPX) Uehara Taisuke (Suwa JPX) Muranaka Tsukasa (Suwa JPX) Kamisuki Shinichi (Suwa JPX) Nose Yasuto (Suwa JPX), Two-valve thin plate micropump.
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  52. Hansson Thord (Balinge SEX) Sjolander Stefan (Uppsala SEX), Valve, especially for fluid handling bodies with microflowchannels.

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  2. Stojanov, Tomas, Cryopreservation of biological cells and tissues.
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  4. Ikushima, Kimiya; Yokoyama, Kazuo, Fluid transporting device using conductive polymer.
  5. Chung, Kwang Hyo; Choi, Yo Han; Lee, Dae Sik; Kim, Young Jun; Jung, Moon Youn; Park, Seon Hee, Magnetic microvalve using metal ball and method of manufacturing the same.
  6. Natarajan, Govindarajan, Manufacturing a microfluid mixer.
  7. Falb, Peter W.; Brancazio, David; France, Eric; Masters, Brett P.; Miller, Michael F.; Ormsby, Joshua R.; Sloan, Walker, Method and apparatus for analyte processing.
  8. Vom, Eduardo; Roy, Tammie Kim; Lewis, Craig Matthews; Hobbs, Benjamin Rawlingson; Hobbs, Simon James, Method, system and apparatus for improved micromanipulation and storage.
  9. Kim, Sung K.; Deciu, Cosmin, Methods and compositions for analyzing nucleic acid.
  10. Hoyal-Wrightson, Carolyn R.; Braun, Andreas; Schmidt, Karsten E, Methods and compositions for the extraction and amplification of nucleic acid from a sample.
  11. Hoyal-Wrightson, Carolyn R.; Braun, Andreas; Schmidt, Karsten E., Methods and compositions for the extraction and amplification of nucleic acid from a sample.
  12. Lee, Min Seob; Yang, Yanfeng, Methods and compositions for universal size-specific PCR.
  13. Cantor, Charles R.; DeSantis, Grace; Mueller, Reinhold; Ehrich, Mathias, Methods and processes for non-invasive assessment of genetic variations.
  14. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays.
  15. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results.
  16. Cantor, Charles R., Methods of nucleic acid sequences analysis using solid supports containing identifier sequences.
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  18. Unger, Marc A.; Chou, Hou-Pu; Thorsen, Todd A.; Scherer, Axel; Quake, Stephen R., Microfabricated elastomeric valve and pump systems.
  19. Putnam, Martin A., Microfluidic assay assemblies and methods of manufacture.
  20. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Microfluidic assay operating system and methods of use.
  21. Putnam, Martin A.; Branciforte, Jeffrey T.; Stanwood, Charles O., Microfluidic assay systems employing micro-particles and methods of manufacture.
  22. Kenis, Paul J. A.; Tice, Joshua D.; Perry, Sarah L.; Roberts, Griffin W., Microfluidic device for preparing mixtures.
  23. Wang, Jing; Woudenberg, Timothy M., Microfluidic device regeneration.
  24. Maltezos, George; Scherer, Axel, Microfluidic devices and related methods and systems.
  25. Henderson, Chester John; Lewis, Craig Matthew; Roy, Tammie Kim; Vom, Eduardo, Micromanipulation and storage apparatus and methods.
  26. Axelrod, Blake Waters; Popescu, Paula; Roukes, Michael L., NEMS sensors for cell force application and measurement.
  27. Wisniewski, Michele E.; Kwong, William H.; Mohsenian, Firouz; Ding, Jian-Hua, Nucleic acid preparation compositions and methods.
  28. Wisniewski, Michele Elizabeth; Kwong, William Hang; Mohsenian, Firouz; Ding, Jian-Hua, Nucleic acid preparation compositions and methods.
  29. Wisniewski, Michele Elizabeth; Kwong, William Hang; Mohsenian, Firouz; Ding, Jian-Hua, Nucleic acid preparation compositions and methods.
  30. Wisniewski, Michele Elizabeth; Kwong, William Hang; Mohsenian, Firouz; Ding, Jian-Hua, Nucleic acid preparation compositions and methods.
  31. Oeth, Paul Andrew; Mahboubi, Payam; Lee, Min Seob, Nucleic acid-based tests for prenatal gender determination.
  32. Putnam, Martin A.; Leamon, John H.; Branciforte, Jeffrey T.; Stanwood, Charles O., PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use.
  33. Roukes, Michael L.; Fon, Chung-Wah; Lee, Wonhee; Tang, Hongxing; Axelrod, Blake Waters; Tan, John Liang, Polymer NEMS for cell physiology and microfabricated cell positioning system for micro-biocalorimeter.
  34. Roukes, Michael L.; Fon, Chung-Wah; Lee, Wonhee; Tang, Hongxing; Axelrod, Blake Waters; Tan, John Liang, Polymer NEMs for cell physiology and microfabricated cell positioning system for micro-biocalorimeter.
  35. Putnam, Martin A., Portable microfluidic assay devices and methods of manufacture and use.
  36. Ehrich, Mathias; Nygren, Anders Olof Herman, Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses.
  37. Ehrich, Mathias; Nygren, Anders Olof Herman; Jensen, Taylor Jacob, Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses.
  38. Ehrich, Mathias; Mistro, Guy Del; Deciu, Cosmin; Chen, Yong Qing; McCullough, Ron Michael; Tim, Roger Chan, Processes and kits for identifying aneuploidy.
  39. Nygren, Anders, Quantification of a minority nucleic acid species.
  40. Nygren, Anders, Quantification of a minority nucleic acid species.
  41. Nygren, Anders, Quantification of a minority nucleic acid species.
  42. Stanwood, Charles; Daigneault, Noel; Branciforte, Jeffrey, Segmented multi-use automated assay cartridge.
  43. Blainey, Paul; Kim, Soohong, Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte.
  44. Blainey, Paul; Kim, Soohong, Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte.
  45. Cantor, Charles R., Single molecule nucleic acid sequence analysis processes and compositions.
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