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Indolinone combinatorial libraries and related products and methods for the treatment of disease 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/404
  • A61K-031/403
  • C07D-403/06
  • C07D-403/00
출원번호 US-0784917 (2004-02-24)
발명자 / 주소
  • Tang,Peng Cho
  • Sun,Connie Li
  • McMahon,Gerald
  • Hirth,Klaus Peter
  • Shawver,Laura Kay
출원인 / 주소
  • Sugen, Inc.
대리인 / 주소
    Foley & Lardner LLP
인용정보 피인용 횟수 : 1  인용 특허 : 39

초록

초록이 없습니다.

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (39)

  1. Rovnyak George C. (Hopewell NJ) Narayanan Venkatachala Lakshmi (Hightstown NJ) Haugwitz Rudiger D. (Titusville NJ), 1,3,Thiazolinyl and 1,3 thiazinyl substituted indolinones.
  2. Eissenstat Michael A. (West Sand Lake NY) Weaver ; III John D. (Northumberland NY) Kuo Gee-Hong (East Greenbush NY) Wentland Mark P. (Colonie NY), 1-cyclopropyl-4-pyridyl-quinolinones.
  3. Shiraishi Tadayoshi (Takasago JPX) Kameyama Keiji (Kakogawa JPX) Domoto Takeshi (Kakogawa JPX) Imai Naohiro (Kakogawa JPX) Shimada Yoshio (Kakogawa JPX) Ariki Yutaka (Himeji JPX) Hosoe Kazunori (Taka, 1-phenyl-3,5-pyrazolidinedione hydroxystyrene compounds which have tyrosine kinase inhibiting activity.
  4. Buzzetti Franco (Monza ITX) Longo Antonio (Milan ITX) Colombo Maristella (Cesano Boscone ITX), 2-oxindole compounds which are useful as tyrosine kinase inhibitors.
  5. Tang Peng Cho ; Sun Li ; McMahon Gerald, 3-(2'-alkoxybenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease.
  6. Tang Peng Cho ; Sun Li ; McMahon Gerald, 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease.
  7. Tang Peng Cho ; Sun Li ; McMahon Gerald, 3-(4'-Bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease.
  8. Tang Peng Cho ; Sun Li ; McMahon Gerald, 3-(4'-dimethylaminobenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease.
  9. Tang Peng Cho ; Sun Li ; McMahon Gerald, 3-(cyclohexanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors.
  10. Connor David T. (Ann Arbor MI) Sircar Ila (Ann Arbor MI) Sircar Jagadish C. (Ann Arbor MI), 3-5-ditertiarybutylphenyl-4-hydroxymethylidene derivatives of 1,3-dihydro-2H-indole-2-ones as antiinflammatory agents.
  11. Tang, Pen Cho; Sun, Li; Miller, Todd Anthony; Liang, Congxin; Tran, Ngoc My; Nguyen, Anh Thi; Nematalla, Asaad, 3-Methylidenyl-2-indolinone modulators of protein kinase.
  12. Tang Peng Cho ; Sun Li ; McMahon Gerald, 3-heteroaryl-2-indolinone compounds for the treatment of disease.
  13. Gerald McMahon ; Peng Cho Tang ; Li Sun, 3-heteroarylidene-2-indolinone protein kinase inhibitors.
  14. Shiraishi Tadayoshi (Takasago JPX) Imai Naohiro (Kakogawa JPX) Domoto Takeshi (Kakogawa JPX) Kameyama Keiji (Kakogawa JPX) Katsumi Ikuo (Kobe JPX) Hidaka Takayoshi (Kobe JPX) Hosoe Kazunori (Takasago, 3-phenylthiomethylstyrene derivative, process for preparing the same, and antiallergic agent and tyrosinekinase inhibiti.
  15. Tang Peng Cho ; Sun Li ; McMahon Gerald, Benzylidene-Z-indoline compounds for the treatment of disease.
  16. Michel Helmut (Mannheim DEX) Kampe Wolfgang (Heddesheim DEX) Strein Klaus (Hemsbach DEX) Bartsch Wolfgang (Viernheim DEX), Beta-blocking oxindole derivatives.
  17. Spada Alfred P. ; Myers Michael R. ; Maguire Martin P. ; Persons Paul E., Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase.
  18. Vallee Bert L. (Brookline MA) Kurachi Kotoku (Ann Arbor MI), CDNA and genes for human angiogenin (angiogenesis factor) and methods of expression.
  19. Buzzetti Franco,ITX ; Brasca Maria Gabriella,ITX ; Longo Antonio,ITX ; Ballinari Dario,ITX, Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors.
  20. Shiraishi Tadayoshi (Takasago) Kameyama Keiji (Kakogawa) Domoto Takeshi (Kakogawa) Imai Naohiro (Kakogawa) Shimada Yoshio (Kakogawa) Ariki Yutaka (Himeji) Hosoe Kazunori (Takasago) Kawatsu Masaji (Ta, Hydroxystyrene compounds having tyrosine kinase inhibiting activity.
  21. Shiraishi Tadayoshi (Takasago JPX) Kameyama Keiji (Kakogawa JPX) Domoto Takeshi (Kakogawa JPX) Imai Naohiro (Kakogawa JPX) Shimada Yoshio (Kakogawa JPX) Ariki Yutaka (Himeji JPX) Hosoe Kazunori (Taka, Hydroxystyrene compounds which are useful as tyrosine kinase inhibitors.
  22. Shiraishi Tadayoshi (Takasago JPX) Kameyama Keiji (Kakogawa JPX) Domoto Takeshi (Kakogawa JPX) Imai Naohiro (Kakogawa JPX) Shimada Yoshio (Kakogawa JPX) Ariki Yutaka (Himeji JPX) Hosoe Kazunoro (Taka, Hydroxystyrene compounds which have useful pharmaceutical utility.
  23. Sircar Ila (Ann Arbor MI) Sircar Jagadish C. (Clarks Summit PA), Imidazole with angiotensin II antagonist properties.
  24. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
  25. Michel Helmut (Mannheim DEX) Marzenell Klaus (Ladenburg DEX) Kampe Wolfgang (Heddesheim DEX) Bartsch Wolfgang (Viernheim DEX) Schaumann Wolfgang (Heidelberg DEX), Indolin-2-one derivatives preparation thereof and intermediates for the preparation thereof.
  26. Tang Peng Cho ; Sun Li ; McMahon Gerald ; Hirth Klaus Peter ; Shawver Laura Kay, Indolinone combinatorial libraries and related products and methods for the treatment of disease.
  27. Tang, Peng Cho; Sun, Li; McMahon, Gerald; Hirth, Klaus Peter; Shawver, Laura Kay, Indolinone combinatorial libraries and related products and methods for the treatment of disease.
  28. Nadler Guy (Saint Gregoie FRX) Martin Michel (Saint Gregoie FRX) Zimmermann Richard (Saint Gregoie FRX), Indolythiadiazines for treating heart failure.
  29. Haga Nobuhiro (Osaka JPX) Inagaki Masanao (Osaka JPX) Matsumoto Saichi (Ikeda JPX) Kamata Susumu (Takarazuka JPX), Method for producing benzylidene derivatives.
  30. Buzzetti Franco (Monza ITX) Longo Antonio (Milan ITX) Colombo Maristella (Cesano Boscone ITX), Methylen-oxindole derivatives compositions and tyrosine kinase inhibition therewith.
  31. Le Baut Guillaume (St Sebastien sur Loire FRX) Nourrisson Marie-Rene (La Chapelle sur Erdre FRX) Renaud de la Faverie Jean-Francois (Le Chesnay FRX) Bizot Espiard Jean-Guy (Paris FRX) Caignard Daniel, New 3-(hydroxybenzylidenyl)-indolin-2-ones.
  32. Kawaguchi Akihiro (Honjo JPX) Sato Atsushi (Saitama JPX) Kajitani Makoto (Saitama JPX) Yasumoto Mitsugi (Honjo JPX) Yamamoto Junji (Tokushima JPX), Oxindole derivative.
  33. Levitzki Alexander (Jerusalem ILX) Gilon Chaim (Jerusalem ILX) Chorev Michael (Jerusalem ILX) Gazit Aviv (Jerusalem ILX), Styryl compounds which inhibit EGF receptor protein tyrosine kinase.
  34. Spada Alfred P. (Lansdale PA) Persons Paul E. (King of Prussia PA) Levitzki Alexander (Jerusalem ILX) Gilon Chaim (Jerusalem ILX), Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase.
  35. Rovnyak George C. (Hopewell NJ), Substituted indolinones.
  36. Battistini Carlo,ITX ; Ballinari Dario,ITX ; Ermoli Antonella,ITX ; Penco Sergio,ITX ; Vioglio Sergio,ITX, Substituted indolylmethylene-oxindole analogues as tyrosine kinase inhibitors.
  37. Larok Richard C. (Ames IA) Babu Srinivasan (Maryland Heights MO), Synthesis of nitrogen heterocycles.
  38. Tang Peng C. ; Harris G. Davis, Synthetic methods for the preparation of indolyquinones.
  39. Buzzetti Franco (Milan ITX) Crugnola Angelo (Varese ITX) Ballinari Dario (Milan ITX) Greco Felicita (Brescia ITX), Vinylene-azaindole derivatives.

이 특허를 인용한 특허 (1)

  1. Riggs-Sauthier, Jennifer; Allums-Donald, Stephanie; Culbertson, Sean M., Polymer-semaxanib moiety conjugates.
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