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Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-049/00
출원번호 US-0672142 (2003-09-26)
발명자 / 주소
  • Yang,David J.
  • Liu,Chun W.
  • Yu,Dong Fang
  • Kim,E. Edmund
출원인 / 주소
  • Board of Regents, The University of Texas System
대리인 / 주소
    Fulbright & Jaworski L.L.P.
인용정보 피인용 횟수 : 14  인용 특허 : 55

초록

초록이 없습니다.

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (55)

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  5. Low Philip Stewart (West Lafayette IN) Horn Mark Alan (Piscataway NJ) Heinstein Peter Frederick (West Lafayette IN), Composition and method for tumor imaging.
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  6. Prakash Ramesh K. ; Clemens Christopher M., Conjugates targeted to the interleukin-2 receptor.
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  7. Unger Evan C. (Tucson AZ) Wu Guanli (Tucson AZ), Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications.
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  8. Myers Andre E. (Genevea CHX) Bichon Daniel (Thorens-Glieres FRX), Cytotoxic drug conjugates and their delivery to tumor cells.
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  9. Tomalia, Donald A.; Dewald, James R., Dense star polymer.
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  10. Tomalia Donald A. (Midland MI) Dewald James R. (Bay City MI), Dense star polymers and dendrimers.
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  11. Tomalia Donald A. (Midland MI) Wilson Larry R. (Midland MI), Dense star polymers for calibrating/characterizing sub-micron apertures.
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  12. Tomalia Donald A. (Midland MI) Dewald James R. (Bay City MI), Dense star polymers having core, core branches, terminal groups.
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  13. Tomalia Donald A. (Midland MI) Dewald James R. (Bay City MI), Dense star polymers having two dimensional molecular diameter.
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  14. Linder Karen (Kingston NJ) Nunn Adrian D. (Ringoes NJ) Nowotnik David P. (Flemington NJ) Ramalingam Kondareddiar (Dayton NJ) DiRocco Richard J. (Allentown NJ) Rumsey William L. (Wyndmoor PA) Pirro Jo, Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety.
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  15. Bergstein Paul L. (Norwood MA) Cheesman Edward H. (Townsend MA) Watson Alan D. (Andover MA), Ester-substituted diaminedithiols and radiolabeled complexes thereof.
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  16. Yang, David J.; Liu, Chun W.; Yu, Dong-Fang; Kim, E. Edmond, Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging.
    상세보기
  17. Martin Francis J. ; Zalipsky Samuel, Fusogenic liposome compositions and method.
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  18. Marchase Richard B. (Birmingham AL) Darbha Sudha (Birmingham AL), Glucose-6-phosphate uptake inhibitors and novel uses thereof.
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  19. Tomalia Donald A. (Midland MI) Dewald James R. (Bay City MI), Hydrolytically-stable dense star polyamine.
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  20. Hart Stephen L.,GBX ; Harbottle Richard P.,GBX, Internalisation of DNA, using conjugates of poly-l-lysine and an integrin receptor ligand.
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  21. Killat George R. (Midland MI) Tomalia Donald A. (Midland MI), Ion exchange/chelation resins containing dense star polymers having ion exchange or chelate capabilities.
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  22. Lee Robert J. ; Huang Leaf, Lipidic vector for nucleic acid delivery.
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  23. Woodle Martin C. (Menlo Park CA) Martin Francis J. (San Francisco CA) Yau-Young Annie (Los Altos CA) Redemann Carl T. (Walnut Creek CA), Liposomes with enhanced circulation time.
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  24. Marzilli Luigi G. ; Lipowska Malgorzata ; Hansen Lory ; Taylor ; Jr. Andrew, Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof.
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  25. Marzilli Luigi Gaetano ; Lipowska Malgorzata ; Hansen Lory ; Taylor ; Jr. Andrew, Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof.
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  26. Srinivasan Ananthachari (Kirkland WA) Fritzberg Alan R. (Edmonds WA) Jones David S. (Seattle WA), Metal radionuclide chelating compounds for improved chelation kinetics.
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  27. Low Philip S. (West Lafayette IN) Horn Mark A. (West Lafayette IN) Heinstein Peter F. (West Lafayette IN), Method for enhanced transmembrane transport of exogenous molecules.
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  28. Low Philip S. (West Lafayette IN) Horn Mark A. (West Lafayette IN) Heinstein Peter F. (West Lafayette IN), Method for enhancing transmembrane transport of exogenous molecules.
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  29. Low Philip S. (West Lafayette IN) Horn Mark A. (West Lafayette IN) Heinstein Peter F. (West Lafayette IN), Method for enhancing transmembrane transport of exogenous molecules.
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  30. Skold Carl N. (Mountain View CA) Shanafelt Armen B. (Redwood City CA) Ghazarossian Vartan (Menlo Park CA) Ullman Edwin F. (Atherton CA), Method for immunochromatographic analysis.
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  31. Low Philip Stewart ; Horn Mark Alan ; Heinstein Peter Frederick, Method for targeting a diagnostic agent to cells.
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  32. Koezuka Masahiro (Nara JPX) Kondo Naohito (Osaka JPX) Oda Sachiko (Osaka JPX) Kobayashi Hisayuki (Osaka JPX) Yasutomi Masayuki (Osaka JPX), Method for testing the sensitivity of anticancer drug.
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  33. Blankenberg Francis G. ; Strauss H. William ; Tait Jonathan F. ; Katsikis Peter D., Method of imaging cell death in vivo.
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  34. Verbruggen Alfons (Leuven BEX), Method of preparing a radiolabelled technetium complex and kit for performing said method.
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  35. Tomalia Donald A. (Midland MI) Stahlbush James R. (Midland MI), Modified dense star polymers.
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  36. Griffiths Gary L. (Morristown NJ) Hansen Hans J. (Mystic Island NJ) Karacay Habibe (Matawan NJ), Modified radioantibody fragments for reduced renal uptake.
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  37. Woo Savio L. C. ; Smith Louis C. ; Cristiano Richard J. ; Gottchalk Stephen ; Sparrow Jim, Nucleic acid transporter systems and methods of use.
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  38. Tomasi Thomas B. (Corrales NM) Anderson William L. (Albuquerque NM), PEG-modified antibody with reduced affinity for cell surface Fc receptors.
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  39. Hansen Hans J. (Mystic Island NJ) Leung Shui-on (Madison NJ) Shevitz Jerry (Livingston NJ) Griffiths Gary L. (Morristown NJ) Govindan Seregulam V. (Summit NJ), Preparation and use of immunoconjugates.
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  40. Papahadjopoulos Demetrios ; Hong Keelung ; Zheng Weiwen, Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery.
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  41. Dean Richard T. ; Lister-James John, Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses.
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  42. Goodman Mark M. (Knoxville TN) Knapp ; Jr. Furn F. (Oak Ridge TN), Radioiodinated glucose analogues for use as imaging agents.
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  46. Crabtree Gerald R. ; Schreiber Stuart L. ; Spencer David M. ; Wandless Thomas J. ; Belshaw Peter, Regulated apoptosis.
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  47. Tomalia Donald A. (Midland MI) Kirchhoff Pamela M. (Midland MI), Rod-shaped dendrimer.
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  48. Butterfield Dennis E. ; Fujii Dennis K. ; Ladd David L. ; Snow Robert A. ; Tan Julia S. ; Toner John L., Segmented chelating polymers as imaging and therapeutic agents.
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  49. Szoka ; Jr. Francis C. ; Haensler Jean,FRX, Self-assembling polynucleotide delivery system comprising dendrimer polycations.
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  50. Boguslaski Robert C. (Elkhart IN) Burd John F. (Elkhart IN) Carrico Robert J. (Elkhart IN), Specific binding assay employing an enzyme-cleavable substrate as label.
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  51. Dean Richard T. ; Lister-James John, Technetium-99m labeled peptides for imaging.
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  52. Thorpe Philip E. ; Edgington Thomas S., Tissue factor compositions and ligands for the specific coagulation of vasculature.
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  53. Sakurai Yasuhisa (Tokyo JPX) Okano Teruo (Chiba JPX) Kataoka Kazunori (Chiba JPX) Yamada Noriko (Tokyo JPX) Inoue Shohei (Tokyo JPX) Yokoyama Masayuki (Tokyo JPX), Water soluble high molecular weight polymerized drug preparation.
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  54. Li Chun ; Wallace Sidney ; Yu Dong-Fang ; Yang David J., Water soluble paclitaxel prodrugs.
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  55. Li Chun ; Wallace Sidney ; Yu Dong-Fang ; Yang David J., Water soluble paclitaxel prodrugs.
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  3. Mugan, John; Murphy, Brian; McWeeney, John, Device for needle biopsy with integrated needle protection.
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  5. McWeeney, John O., Endoscopic ultrasound-guided biliary access system.
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  6. Yang, David J.; Liu, Chun W.; Yu, Dong Fang; Kim, E. Edmund, Ethylenedicysteine (EC)-drug conjugates compositions and methods for tissue specific disease imaging.
    상세보기
  7. Yang, David J.; Liu, Chun W.; Yu, Dong Fang; Kim, E. Edmund, Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging.
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  8. Yang, David J.; Liu, Chun W.; Yu, Dong Fang; Kim, E. Edmund, Metal ion-labeled bis-aminoethanethiol-targeting ligand conjugates, compositions, and methods for tissue-specific disease imaging.
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  9. Saidi,Olivier; Verbel,David A.; Yan,Lian, Methods and systems for predicting occurrence of an event.
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  10. Yang, David J.; Yu, Dong-Fang; Oh, Chang-Sok; Bryant, Jr., Jerry L., N2S2 chelate-targeting ligand conjugates.
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  11. Mugan, John; Murphy, Brian; McWeeney, John, Needle biopsy device.
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  12. Mugan, John; Murphy, Brian; McWeeney, John O., Needle biopsy device.
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  13. McWeeney, John; Kelly, Micheal, Needle biopsy device with exchangeable needle and integrated needle protection.
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  14. Rosenblum, Michael, Vascular endothelial growth factor fusion constructs used to inhibit osteoclastogenesis.
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