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Compounds and uses thereof in modulating amyloid beta 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/505
  • C07D-277/20
  • C07D-277/00
출원번호 US-0846941 (2004-05-14)
발명자 / 주소
  • Cheng,Soan
  • Comer,Daniel D.
  • Mao,Long
  • Balow,Guity P.
  • Pleynet,David
출원인 / 주소
  • Torreypines Therapeutics, Inc.
대리인 / 주소
    Foley & Lardner LLP
인용정보 피인용 횟수 : 15  인용 특허 : 51

초록

초록이 없습니다.

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (51)

  1. Yu Cheng-Der (Mountain View CA), Acetal stabilized prostaglandin compositions.
  2. Yuzhakov Vadim Vladimirovich ; Sherman Faiz Feisal ; Owens Grover David ; Gartstein Vladimir, Apparatus and method for using an intracutaneous microneedle array.
  3. Yu Cheng-Der (Mountain View CA) Bruenner Ursula (Palo Alto CA), Carbonate diester solutions of PGE-type compounds.
  4. Yu Cheng-Der (Mountain View CA) Bruenner Ursula (Palo Alto CA), Carbonate diester solutions of PGE-type compounds.
  5. Unger Evan C., Charged lipids and uses for the same.
  6. Cook Peter B. (Standon GB2) Hunt John H. (Theydon Bois GB2), Chemical compounds.
  7. Kalvelage John D. (Lynchburg VA), Child resistant package assembly for dispensing pharmaceutical medications.
  8. Shah Navnit Hargovindas ; Railkar Aruna M. ; Phuapradit Wantanee, Colon targeted delivery system.
  9. Tamarkin Lawrence ; Paciotti Guilio F., Composition and method for delivery of biologically-active factors.
  10. Gurewich Victor, Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases.
  11. Yatvin Milton B. ; Stowell Michael H. B. ; Gallicchio Vincent S. ; Meredith Michael J., Covalent microparticle-drug conjugates for biological targeting.
  12. Kosak Kenneth M., Cyclodextrin polymers for carrying and releasing drugs.
  13. Fujii Kimihiro,JPX ; Tanaka Kazuo,JPX ; Ikawa Kazuya,JPX ; Ikeura Yasuhiro,JPX ; Yamasoto Shinji,JPX, Dermatological patch and process for producing thereof.
  14. Hanson Stephen R. ; Scott Neal A. ; King ; III Spencer B. ; Markou Christos, Device and method for non-occlusive localized drug delivery.
  15. Hanson Stephen R. ; Scott Neal A. ; King ; III Spencer B. ; Harker Laurence A., Device for local drug delivery and methods for using the same.
  16. Thompson Geoffrey F. (Sunnyvale CA), Dialkylated glycol compositions and medicament preparations containing same.
  17. Steliou Kosta, Drug mitochondrial targeting agents.
  18. Haynes Duncan H. ; Bodeker Ben H. ; Kline Mark D., Drug releasing surgical implant or dressing material.
  19. Ostrow Alvin S.,ILX, Electrophoretic cuff apparatus drug delivery system.
  20. Flower Ronald J. ; Devine James Michael, Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit.
  21. Calanchi Massimo,ITX ; Zema Marco,ITX ; Brunetti Gabriele,ITX ; Giorgetti Enzo,ITX, Method for targeted and controlled release of drugs in the intestinal tract and more particularly in the colon.
  22. Carter Douglas V. (Lenoir NC), Method of packaging and sterilizing a pharmaceutical product.
  23. D'Angelo Joseph P. ; Schur Henry, Method of transdermally administering high molecular weight drugs with a polymer skin enhancer.
  24. Cook Peter B. (Standon GB2) Hunt John H. (Theydon Bois GB2), Micronized aerosol steroids.
  25. Jacobsen Stephen C. ; Wyatt Roland ; Peterson Stephen C. ; Petelenz Tomasz J., Multipathway electronically-controlled drug delivery system.
  26. Carter Douglas V. (Lenoir NC), Packaged pharmaceutical product.
  27. Chen Hongming ; Langer Robert S., Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery.
  28. Venkateshwaran Srinivasan ; Fikstad David ; Ebert Charles D., Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents.
  29. Yu Cheng-Der (Mountain View CA), Propylene glycol diester solutions of PGE-type compounds.
  30. Alan D. Snow, Rodent models of human amyloidoses.
  31. Cook Peter Barry (Standon EN) Hunt John Harold (Theydon Bois EN), Steroidal aerosol compositions and process for the preparation thereof.
  32. Fey Peter (Wuppertal DEX) Kramer Thomas (Wuppertal DEX) Dressel Jurgen (Radevormwald DEX) Hanko Rudolf (Essen DEX) Hubsch Walter (Wuppertal DEX) Muller Ulrich (Wuppertal DEX) Muller-Gliemann Matthias, Substituted monopyridylmethyl derivatives.
  33. Unger Evan C. ; Fritz Thomas A. ; Matsunaga Terry ; Ramaswami VaradaRajan ; Yellowhair David ; Wu Guanli, Targeted gas and gaseous precursor-filled liposomes.
  34. Langer Robert S. ; Chen Hongming, Targeted polymerized liposomes for improved drug delivery.
  35. Friend David R. ; Ng Steve ; Sarabia Rafael E. ; Weber Thomas P. ; Geoffroy Jean-Marie, Taste-masked microcapsule compositions and methods of manufacture.
  36. Schuster Jeffrey A. ; Flaim Christopher J., Temperature controlling device for aerosol drug delivery.
  37. Norris James ; Clawson Gary ; Westwater Caroline ; Schofield David ; Schmidt Michael ; Hoel Brian ; Dolan Joseph ; Pan Wei-Hua, Tissue-specific and pathogen-specific toxic agents and ribozymes.
  38. Neumann Bernhard,ATX, Track soundproofing arrangement.
  39. Stanley Theodore ; Hull Wade ; Rigby Larry, Transdermal drug patch with attached pocket for controlled heating device.
  40. Burton Scott Allison ; Tata Shahnaz, Transdermal patch.
  41. Wick John J. ; Weimann Ludwig J. ; Pollock Wayne C., Transdermal patch incorporating a polymer film incorporated with an active agent.
  42. McConlogue Lisa C. (San Francisco CA) Zhao Jun (San Diego CA), Transgenic animals harboring APP allele having swedish mutation.
  43. Cordell Barbara (Palo Alto CA), Transgenic mice displaying the amyloid-forming pathology of alzheimer\s disease.
  44. Neve Rachael L. (Irvine CA), Transgenic mice expressing the neurotoxic C-terminus of b 상세보기
  • Wadsworth Samuel ; Snyder Benjamin ; Wei Cha-Mer ; Leibowitz Paul J., Transgenic mouse expressing APP.sub.770.
  • Benson Merrill D. ; Murrell Jill ; Farlow Martin ; Ghetti Bernardino, Transgenic mouse expressing APP770-V717F.
  • Singh Gurparlash ; Chen Howard Y. ; Heavens Robert P.,GBX ; Sirinathsinghji Dalip J. S.,GBX ; Smith David W.,GBX ; Trumbauer Myrna E. ; Van Der Ploeg Leonardus H. T. ; Vongs Aurawan ; Zheng Hui, Transgenic mouse expressing a familial form of human amyloid precursor protein.
  • Sato Masahiro,JPX ; Kobayashi Takashi,JPX ; Tada Norihiro,JPX ; Shoji Mikio,JPX ; Kawarabayashi Takeshi,JPX, Transgenic mouse expressing an .beta.-Amyloid transgene.
  • Zheng Hui ; Chen Howard Y. ; Trumbauer Myrna E. ; van der Ploeg Leonardus H. T. ; Seabrook Guy,GBX ; Sirinathsinghji Dalip,GBX, Transgenic mouse having a disrupted amyloid precursor protein gene.
  • McLonlogue Lisa C. ; Zhao Jun, Transgenic rodents harboring APP allele having swedish mutation.
  • Tanimoto, Norihiko; Hasegawa, Yasushi; Haga, Nobuhiro, Tricyclic compound.
  • 이 특허를 인용한 특허 (15)

    1. Altman, Michael D.; Childers, Kaleen Konrad; Di Francesco, Maria Emilia; Ellis, John Michael; Fischer, Christian; Grimm, Jonathan; Haidle, Andrew M.; Kattar, Solomon D.; Northrup, Alan B.; Otte, Ryan D.; Petrocchi, Alessia; Schell, Adam J.; Zhou, Hua, Aminopyrimidines as Syk inhibitors.
    2. Deschenes, Denis; Altman, Michael D.; Ellis, John Michael; Fischer, Christian; Haidle, Andrew M.; Kattar, Solomon D.; Northrup, Alan B.; Schell, Adam J.; Smith, Graham F.; Taoka, Brandon M.; Bienstock, Corey; Di Francesco, Maria Emilia; Donofrio, Anthony; Peterson, Scott; Spencer, Kerrie B.; Jewell, James Patrick; Ali, Amjad; Bennett, David Jonathan; Dang, Qun; Wai, John, Bipyridylaminopyridines as Syk inhibitors.
    3. Wagner, Steven L.; Cheng, Soan; Mobley, William C.; Tanzi, Rudolph E., Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms.
    4. Esposito, Luke A.; Yadon, Marisa C.; Cummings, Joel; Hudson, F. Michael; Lake, Thomas; Hefti, Franz F.; Golding, Geoffrey; Choi, Seok-Rye; Li, Ximin; Snow, Alan D.; Hu, Qubai; Cam, Judy, Compounds for the treatment of neurodegenerative diseases.
    5. Koike, Tatsuki; Nakamura, Minoru; Takai, Takafumi; Kajita, Yuichi; Kamata, Makoto, Fused triazoles for the treatment or prophylaxis of mild cognitive impairment.
    6. Tanzi, Rudolph E.; Wagner, Steven L.; Cheng, Soan; Mobley, William C., Gamma-secretase modulators.
    7. Koike, Tatsuki; Nakamura, Minoru; Tomata, Yoshihide; Takai, Takafumi; Hoashi, Yasutaka; Kajita, Yuichi; Tsukamoto, Tetsuya; Kamata, Makoto, Heterocyclic compound and use thereof.
    8. Bernales, Sebastian; Lindquist, Jeffrey; Guha, Mausumee, Heterocyclic compounds and methods of use.
    9. Chakravarty, Sarvajit; Rai, Roopa; Pham, Son Minh; Pujala, Brahmam; Jangir, Ramniwas; Guguloth, Rambabu; Sharma, Vijay Kumar, Heterocyclic compounds and methods of use.
    10. Pujala, Brahmam; Jangir, Ramniwas; Guguloth, Rambabu; Shinde, Bharat Uttam; Rai, Roopa; Pham, Son Minh; Bernales, Sebastian; Lindquist, Jeffrey; Guha, Mausumee; Kallem, Satyanarayana; Bhatt, Bhawana; Bhagwat, Vikas Ramdas, Heterocyclic compounds and methods of use.
    11. Yamaguchi, Yoshimasa; Matsuno, Toshiyuki; Saitoh, Kenichi, Methods for treating depression, neurodegeneration, inhibiting amyloid β deposition, delaying senescence, and extending life spans with heterocyclic compounds.
    12. Altman, Michael D.; Di Francesco, Maria Emilia; Haidle, Andrew M.; Otte, Ryan D.; Ellis, John Michael; Childers, Kaleen Konrad; Northrup, Alan B.; Wang, Liping, Pyridyl aminopyridines as Syk inhibitors.
    13. Shapiro, Gideon; Chesworth, Richard, Tetrasubstituted benzenes.
    14. Shapiro, Gideon; Chesworth, Richard, Tetrasubstituted benzenes.
    15. Shapiro, Gideon; Chesworth, Richard, Tetrasubstituted benzenes.
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