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Screening small molecule drugs using neural cells differentiated from human embryonic stem cells 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-005/00
  • C12N-005/02
출원번호 US-0157288 (2002-05-28)
발명자 / 주소
  • Carpenter,Melissa K.
  • Denham,Jerrod J.
  • Inokuma,Margaret S.
  • Thies,R. Scott
출원인 / 주소
  • Geron Corporation
인용정보 피인용 횟수 : 30  인용 특허 : 17

초록

초록이 없습니다.

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (17)

  1. Reid Lola M. ; Agelli Maria ; Ochs Andreas, Compositions comprising hepatocyte precursors.
  2. Laurance Megan E. ; Knaack David ; Fiore Deborah M. ; Hegre Orion D., Glucose responsive insulin secreting .beta.-cell lines and method for producing same.
  3. Lakshmi Rambhatla ; Melissa K. Carpenter, Hepatocyte lineage cells derived from pluripotent stem cells.
  4. Carpenter Melissa, Human CNS neural stem cells.
  5. Gearhart John D. ; Shamblott Michael Joseph, Human embryonic pluripotent germ cells.
  6. Anderson David J. (Altadena CA) Stemple Derek L. (Newton MA), Immoralized neural crest stem cells and methods of making.
  7. Johe Karl K., In vitro generation of differentiated neurons from cultures of mammalian multipotential CNS stem cells.
  8. Weiss Samuel,CAX ; Reynolds Brent,CAX ; Hammang Joseph P. ; Baetge E. Edward, In vitro growth and proliferation of multipotent neural stem cells and their progeny.
  9. Weiss Samuel,CAX ; Reynolds Brent,CAX, In vitro induction of dopaminergic cells.
  10. Carpenter, Melissa K., Making neural cells for human therapy or drug screening from human embryonic stem cells.
  11. Anderson David J. ; Stemple Derek L., Mammalian multipotent neural stem cells.
  12. Anderson David J. ; Stemple Derek L., Mammalian multipotent neural stem cells.
  13. Gage Fred H. ; Ray Jasodhara, Method for production of neuroblasts.
  14. Gay David A. (San Diego CA), Method of isolating a lineage specific stem cell in vitro.
  15. Thomson, James A; Marshall, Vivienne S.; Swiergiel, Jennifer J., Method of making embryoid bodies from primate embryonic stem cells.
  16. Thomson James A., Primate embryonic stem cells.
  17. Uchida Nobuko, Use of collagenase in the preparation of neural stem cell cultures.

이 특허를 인용한 특허 (30)

  1. Tai, Yu-Chong; Lu, Bo; Humayun, Mark, 3-Dimensional parylene scaffold cage.
  2. Tai, Yu-Chong; Lu, Bo; Humayun, Mark, 3-dimensional parylene scaffold cage.
  3. Colton, Clark K.; Gleason, Karen K.; Coclite, Anna M.; Dilenno, Amanda R., Articles and methods for stem cell differentiation.
  4. Humayun, Mark S.; Ahuja, Ashish; Tai, Yu-Chong; Hinton, David R.; Grubbs, Robert H.; Clegg, Dennis O.; Johnson, Lincoln Vallance; Hikita, Sherry T., Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.
  5. Humayun, Mark; Ahuja, Ashish; Tai, Yu-Chong; Hinton, David; Grubbs, Robert; Clegg, Dennis; Johnson, Lincoln V.; Hikita, Sherry T., Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.
  6. Wichterle, Hynek; Jessell, Thomas M.; Peljto, Mirza, Caudal motor neuron derived from embryonic stem cells under conditions essentially free of any retinoid.
  7. Amit, Michal; Itskovitz-Eldor, Joseph, Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state.
  8. Amit, Michal; Itskovitz-Eldor, Joseph, Media for culturing stem cells.
  9. Amit, Michal; Itskovitz-Eldor, Joseph, Medium comprising transforming growth factor beta 1 and basic fibroblast growth factor.
  10. Amit, Michal; Itskovitz-Eldor, Joseph, Medium comprising transforming growth factor beta 1 and basic fibroblast growth factor.
  11. Amit, Michal; Itskovitz-Eldor, Joseph, Medium comprising transforming growth factor β1 and basic fibroblast growth factor.
  12. Colton, Clark K.; Dilenno, Amanda; Millman, Jeffrey R., Method for differentiating human embryonic stem cells into β-cells for the treatment of type I diabetes.
  13. Kelleher-Andersson, Judith; Johe, Karl K., Method for screening neurogenic agents.
  14. Colton, Clark K.; Powers, Daryl E.; Millman, Jeffrey R., Methods and compositions for enhanced differentiation from embryonic stem cells.
  15. Colton, Clark K.; Millman, Jeffrey R., Methods and compositions for increased safety of stem cell-derived populations.
  16. Colton, Clark K.; Millman, Jeffrey R., Methods and compositions for increased safety of stem cell-derived populations.
  17. Krause, Karl-Heinz; Preynat-Seauve, Olivier, Methods and compositions related to dopaminergic neuronal cells.
  18. Amit, Michal; Itskovitz-Eldor, Joseph, Methods of expanding embryonic stem cells in a suspension culture.
  19. Amit, Michal; Itskovitz-Eldor, Joseph, Methods of expanding embryonic stem cells in a suspension culture.
  20. Carpenter, Melissa K.; Thies, R. Scott, Neural cell populations from primate pluripotent stem cells.
  21. Carpenter, Melissa K.; Thies, R. Scott, Neural cell populations from primate pluripotent stem cells.
  22. Carpenter, Melissa K., Neural progenitor cell populations.
  23. Carpenter, Melissa K., Neural progenitor cell populations.
  24. Carpenter, Melissa K., Neural progenitor cell populations.
  25. Przedborski, Serge; Wichterle, Hynek; Nagai, Makiko; Jessell, Thomas M., Stem cell-based culture system for drug development.
  26. Jessell, Thomas; Wichterle, Hynek; Wilson, Sara, Systems and methods for screening for modulators of neural differentiation.
  27. Tai, Yu-Chong; Lu, Bo; Humayun, Mark, Ultrathin parylene-C semipermeable membranes for biomedical applications.
  28. Carpenter, Melissa K.; Thies, R. Scott, Use of TGF beta superfamily antagonists and neurotrophins to make neurons from embryonic stem cells.
  29. Carpenter, Melissa K.; Thies, R. Scott, Use of TGF beta superfamily antagonists to make dopaminergic neurons from embryonic stem cells.
  30. Carpenter, Melissa K.; Thies, R. Scott, Use of cyclic AMP and ascorbic acid to produce dopaminergic neurons from embryonic stem cells.
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