Apparatus and processes for preventing or delaying one or more symptoms of presbyopia
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-018/20
출원번호
US-0980700
(2004-11-02)
등록번호
US-7252662
(2007-08-07)
발명자
/ 주소
McArdle,George J.
Olejniczak,Brian L.
Kuszak,Jerry R.
출원인 / 주소
Lenticular Research Group LLC
대리인 / 주소
McAndrews, Held & Malloy, Ltd.
인용정보
피인용 횟수 :
39인용 특허 :
31
초록▼
The present invention generally relates to an apparatus and processes for preventing or delaying presbyopia. More particularly, the present invention relates to processes and apparatus for ablating epithelial cells in the germinative zone or the pregerminative zone of the crystalline lens of the eye
The present invention generally relates to an apparatus and processes for preventing or delaying presbyopia. More particularly, the present invention relates to processes and apparatus for ablating epithelial cells in the germinative zone or the pregerminative zone of the crystalline lens of the eye so that onset or progression of presbyopia or one or more symptoms is delayed or prevented.
대표청구항▼
We claim: 1. A process for preventing or delaying presbyopia by ablating epithelial cells in a crystalline lens, the process comprising the step of ablating epithelial cells in the germinative zone or the pregerminative zone of the crystalline lens using a laser, wherein the epithelial cells are ab
We claim: 1. A process for preventing or delaying presbyopia by ablating epithelial cells in a crystalline lens, the process comprising the step of ablating epithelial cells in the germinative zone or the pregerminative zone of the crystalline lens using a laser, wherein the epithelial cells are ablated symmetrically. 2. The process of claim 1, wherein ablation points are made in the germinative zone of the crystalline lens. 3. The process of claim 1, wherein ablation points are made in the pregerminative zone of the crystalline lens. 4. The process of claim 1, wherein the epithelial cells are ablated along suture lines of the crystalline lens. 5. The process of claim 1, wherein an even number of ablation points are made around the crystalline lens. 6. The process of claim 1, wherein the crystalline lens has a circumference, and the process comprises making ablation points symmetrically around essentially the entire circumference. 7. The process of claim 1, wherein at least about 10% of the epithelial cells in the germinative zone of the crystalline lens are ablated. 8. The process of claim 1, wherein the epithelial cells are ablated without decreasing the equatorial diameter of the crystalline lens. 9. The process of claim 1, wherein the epithelial cells are ablated without forming a cataract or an astigmatic condition. 10. The process of claim 1, further comprising the step of administering to the crystalline lens a biochemical flag or indicator that identifies the epithelial cells which are in a process of mitosis. 11. The process of claim 1, wherein a pre-ablative growth rate is determined for the crystalline lens, and the epithelial cells are sufficiently ablated to establish a growth rate that is about 95% or less of the pre-ablative growth rate. 12. A process for preventing or delaying one or more symptoms of presbyopia in a patient, the process comprising the steps of: selecting a patient prior to detecting a symptom of presbyopia in the patient, and ablating epithelial cells in the germinative zone or the pregerminative zone of the crystalline lens using a laser. 13. The process of claim 12, wherein the patient is selected based on an increased risk factor for presbyopia. 14. The process of claim 12, wherein the patient is selected based on age. 15. The process of claim 12, wherein the epithelial cells are symmetrically ablated. 16. The process of claim 12, wherein at least about 10% of the epithelial cells in the germinative or pregerminative zones of the crystalline lens are ablated. 17. The process of claim 12, further comprising the step of administering to the crystalline lens a biochemical flag or indicator that identifies the epithelial cells which are in a process of mitosis. 18. A process for preventing or delaying presbyopia by ablating epithelial cells in a crystalline lens, the process comprising the step of ablating epithelial cells in the pregerminative zone of the crystalline lens using a laser. 19. The process of claim 18, wherein the epithelial cells are ablated along suture lines of the crystalline lens. 20. The process of claim 18, wherein an even number of ablation points are made around the crystalline lens. 21. The process of claim 18, wherein an odd number of ablation points are made around the crystalline lens. 22. The process of claim 18, wherein the crystalline lens has a circumference, and the process comprises making ablation points around essentially the entire circumference. 23. The process of claim 18, wherein at least about 10% of the epithelial cells in the pregerminative zone of the crystalline lens are ablated.
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이 특허에 인용된 특허 (31)
Gross, Erik, Ablation shape for the correction of presbyopia.
Odrich, Marc; Greenberg, Kenneth; Legerton, Jerome A.; Munnerlyn, Charles R.; Shimmick, John K., Method and systems for laser treatment of presbyopia using offset imaging.
Myers, Raymond I, Laser methods for creating an antioxidant sink in the crystalline lens for the maintenance of eye health and physiology and slowing presbyopia development.
Myers, Raymond I, Laser methods for creating an antioxidant sink in the crystalline lens for the maintenance of eye health and physiology and slowing presbyopia development.
Naranjo-Tackman, Ramón; Kuri, Jorge Octavio Villar; Frey, Rudolph W., Laser system and method for astigmatic corrections in association with cataract treatment.
Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J.; Zdenek, Gene W., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Jacobson, Harry R. A.; Griffis, III, Jack C.; Cox, Mark A.; Williamson, Douglas C.; Zdenek, Gene W.; Richardson, Peter J.; Smolek, Michael K.; Soloway, Barrie D.; Bare, Rex O.; Scherer, Andrew J.; Payne, Timothy J., Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods.
Frey, Rudolph W.; Gray, Gary P.; Zepkin, Neil; Downes, Jr., George R.; De Castro, Jorge A.; Kuszak, Jerome R.; Olmstead, Richard Ty, System and apparatus for delivering a laser beam to the lens of an eye.
Frey, Rudolph W.; Gray, Gary P.; Pape, Dennis R.; Downes, Jr., George R.; De Castro, Jorge A.; Kuszak, Jerome R., System and apparatus for treating the lens of an eye.
Frey, Rudolph W.; Gray, Gary P.; Kuszak, Jerome R., System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser.
Frey, Rudolph W.; Gray, Gary P.; Pape, Dennis R.; Subramaniam, Hari; Kuszak, Jerome R., System and method for providing the shaped structural weakening of the human lens with a laser.
Frey, Rudolph W.; Olmstead, Richard Ty; Gray, Gary P.; Bott, Steven E.; Strobel, James, System and method of scan controlled illumination of structures within an eye.
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