[특허]Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof

Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	C12N-009/10 C12N-001/20 C12N-015/00 C07H-021/04 C07H-021/00
출원번호	US-0761905 (2004-01-21)
등록번호	US-7259002 (2007-08-21)
발명자 / 주소	Feder,John N. Nelson,Thomas C. Chen,Jian Meegalla,Rupalie Ramaker,Michael Cheng,Dong
출원인 / 주소	Bristol Myers Squibb Company
인용정보	피인용 횟수 : 0 인용 특허 : 108

초록 ▼

The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing MGAT3 polypeptides, fragments, and homologues thereof. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

대표청구항 ▼

What is claimed is: 1. An isolated nucleic acid molecule comprising the polynucleotide of SEQ ID NO:1. 2. A recombinant vector comprising said isolated nucleic acid molecule of claim 1. 3. An isolated recombinant host cell comprising said recombinant vector of claim 2. 4. An isolated recombinant host cell comprising a polypeptide encoded by the isolated nucleic acid of claim 1. 5. A method of making an isolated polypeptide comprising: (a) culturing said recombinant host cell of claim 3 under conditions such that said polypeptide is expressed; and (b) recovering said polypeptide. 6. The nucleic acid molecule of claim 1 wherein the nucleic acid is included in at least one of ATCC Deposit numbers PTA-4454 or PTA-4803.

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof 원문보기

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연합인증

Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof 원문보기

초록 ▼

대표청구항 ▼

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