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Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in

Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.

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What is claimed is: 1. A method for treating presbyopia of a patient having an eye, the eye having a pupil, the method comprising inducing a presbyopia-mitigating quantity of high-order negative spherical aberration in the eye, the eye having an induced negative spherical aberration extending acros

What is claimed is: 1. A method for treating presbyopia of a patient having an eye, the eye having a pupil, the method comprising inducing a presbyopia-mitigating quantity of high-order negative spherical aberration in the eye, the eye having an induced negative spherical aberration extending across the pupil. 2. The method of claim 1, wherein the presbyopia-mitigating quantity is in a range from about 0.05 to about 0.4 microns of negative spherical aberration across the pupil. 3. The method of claim 2, wherein the presbyopia-mitigating quantity is in a range from about 0.1 to about 0.3 microns of negative spherical aberration across the pupil. 4. The method of claim 3, wherein the presbyopia-mitigating quantity is in a range from about 0.15 to about 0.25 microns of negative spherical aberration across the pupil. 5. The method of claim 1, wherein the spherical aberration comprises a radially symmetric negative spherical asphericity. 6. The method of claim 5, wherein the spherical aberration correspond to at least one high order Zemike polynomial coefficient. 7. The method of claim 6, wherein the spherical aberration consists of a plurality of high order Zernike polynomial coefficients. 8. The method of claim 7, further comprising combining the spherical aberration with a plurality of wavefront Zernike coefficients, the wavefront Zernike coefficients defining a refractive defect-correcting prescription for the eye, and wherein the combined presbyopia-mitigating quantity of spherical aberration and refractive defect-correcting prescription are induced in the eye by at least one of reshaping a cornea, inserting a lens into the eye, positioning a lens in front of a cornea, laser eye surgery, LASEK, LASIK, photorefractive keratectomy, a contact lens, a scleral lens, an intraocular lens, a phacik intraocular lens, or a combination thereof. 9. The method of claim 1, further comprising measuring refractive aberrations of the eye with a wavefront aberrometer; determine wavefront Zernike coefficients of the measured refractive aberrations; and defining a prescription for the patient by combining the wavefront Zernike coefficients with at least one high-order Zernike coefficient corresponding to the presbyopia-mitigating quantity of spherical aberration. 10. The method of claim 1, wherein the eye has a cornea and a retina and wherein the treated eye is configured so that an image in a plane between the cornea and the retina, of a point source at a viewing distance from the eye, has a central area with a central intensity surrounded by a peripheral area with a peripheral intensity, the central intensity being higher than the peripheral intensity. 11. The method of claim 10, further comprising sharpening the image using residual accommodation of the eye. 12. The method of claim 1, further comprising: identifying the presbyopia-mitigating quantity of spherical aberration; and determining a presbyopia prescription providing the identified quantity of spherical aberration; wherein the presbyopia-mitigating quantity of spherical aberration is induced by superimposing the determined presbyopia prescription on the eye. 13. A method for treating presbyopia in a patient having an eye with a pupil, the method comprising altering refraction of the eye so that the altered eye has a negative spherical aberration in a range from about 0.1 to about 0.3 microns across the pupil so that the effect of the presbyopia is mitigated. 14. A method for planning a presbyopia treatment for an eye of a patient having a pupil where a plurality of Zernike polynomial coefficients correspond to measured aberrations of the eye, the method comprising deriving a prescription for the eye by combining the Zernike polynomial coefficients with at least one high-order Zemike polynomial coefficient of a refractive modification corresponding to a presbyopia-mitigating negative spherical aberration exhibited by the eye and extending across the pupil. 15. A system for treating presbyopia of an eye, the eye having a pupil, the system comprising a prescription generator module coupled to an output, the prescription generator module defining a presbyopia-mitigating quantity of high-order negative spherical aberration for the eye, such that the eye has induced negative spherical aberration extending across the pupil, the output configured for communication to a lens producing or eye modifying assembly. 16. The system of claim 15, wherein the prescription generator has an input, and further comprising: a wavefront system coupled to the input of the prescription generator, the wavefront system generating a plurality of refractive Zemike coefficients corresponding to sensed aberrations of an eye; the lens producing or eye modifying assembly, including an ablative laser beam for imposing a prescription on the eye by directing a pattern of laser energy toward a cornea of the eye; wherein the prescription generator combines the refractive Zernike coefficients with at least one presbyopia-mitigating Zernike coefficients, the at least one presbyopia-mitigating Zernike coefficient comprising at least one high-order Zernike coefficient corresponding to the presbyopia-mitigating quantity of spherical aberration, so as to provide the eye with between about 0.1 and about 0.3 microns of negative spherical aberration across the pupil.