Permanent magnet solenoid pump for an implantable therapeutic substance delivery device
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-009/22
A61M-001/00
출원번호
US-0952894
(2001-09-14)
등록번호
US-7288085
(2007-10-30)
발명자
/ 주소
Olsen,James M.
출원인 / 주소
Medtronic, Inc.
대리인 / 주소
Mueting, Raasch & Gebhardt, P.A.
인용정보
피인용 횟수 :
60인용 특허 :
38
초록▼
A medical device known as an implantable therapeutic substance delivery device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spastisity, cancer, an
A medical device known as an implantable therapeutic substance delivery device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spastisity, cancer, and many other conditions. The therapeutic substance delivery device has a permanent magnet solenoid pump that is energy efficient, accurate, small, compatible with therapeutic substances, and has many other improvements. The implantable therapeutic substance delivery device has a housing, a therapeutic substance reservoir, a power source, electronics, and a permanent magnet solenoid pump. The therapeutic substance reservoir is configured to contain a therapeutic substance and is coupled to the housing. The power source is carried in the housing to power the electronics and solenoid pump. The electronics are coupled to the solenoid pump and the solenoid pump is coupled to the therapeutic substance reservoir. The permanent magnet solenoid pump is configured for pumping therapeutic substance from the therapeutic substance reservoir through an infusion outlet at a programmed infusion rate. Many embodiments of the permanent magnet solenoid pump and its methods of operation are possible.
대표청구항▼
What is claimed is: 1. An implantable therapeutic substance delivery device comprising: a housing; a therapeutic substance reservoir; a power source carried in the housing; electronics carried in the housing, the electronics coupled to the power source; and, a permanent magnet solenoid pump carried
What is claimed is: 1. An implantable therapeutic substance delivery device comprising: a housing; a therapeutic substance reservoir; a power source carried in the housing; electronics carried in the housing, the electronics coupled to the power source; and, a permanent magnet solenoid pump carried in the housing and coupled to the electronics, the permanent magnet solenoid pump configured for pumping a therapeutic substance from the therapeutic substance reservoir through an infusion outlet, wherein the permanent magnet solenoid pump comprises a pump piston movable within a pump cylinder, a permanent magnet carried on the pump piston, a first coil formed around the pump cylinder and positioned adjacent a first pole of the permanent magnet, a second coil formed around the pump cylinder and positioned adjacent a second pole of the permanent magnet, and a biasing element biasing the pump piston in one direction within the pump cylinder. 2. A device according to claim 1, wherein the permanent magnet solenoid pump comprises a pumping chamber proximate the infusion outlet, an inlet valve through which therapeutic substance passes into the pumping chamber, and an outlet valve through which therapeutic substance passes into the infusion outlet from the pumping chamber. 3. A device according to claim 2, wherein the biasing element biases the pump piston towards the inlet valve. 4. A device according to claim 3, wherein the inlet valve is sealed when the biasing element biases the pump piston against the inlet valve. 5. A device according to claim 2, wherein the biasing element provides a biasing force sufficient to overcome frictional losses during movement of the pump piston within the pump cylinder, open the outlet valve of the pumping chamber, open the inlet valve of the pumping chamber, and overcome pressure losses between the infusion outlet and an infusion site to which the therapeutic substance is to be delivered. 6. A device according to claim 2, wherein the inlet valve is carried on an end of the pump piston. 7. A device according to claim 2, wherein the biasing element is located proximate a flint end of the pump piston and the pumping chamber is located proximate a second end of the pump piston. 8. A device according to claim 1, wherein the biasing element biases the pump cylinder towards the infusion outlet. 9. A device according to claim 1, wherein the biasing element exerts substantially the sole force on the pump piston to expulse therapeutic substance through the infusion outlet. 10. A device according to claim 1, wherein the biasing element comprises a mechanical spring. 11. A device according to claim 1, wherein the biasing element is located proximate an end of the pump cylinder that is opposite from the infusion outlet. 12. A device according to claim 1, wherein the permanent magnet solenoid pump comprises a therapeutic substance flow path that is composed of therapeutic substance compatible material. 13. A device according to claim 1, wherein the permanent magnet solenoid pump comprises N coils fanned around the pump cylinder and N-1 magnets carried on the pump piston, wherein N is an integer in the range from 3 to 10. 14. A device according to claim 1, wherein the therapeutic substance reservoir is located outside of the housing. 15. A device according to claim 1, wherein the therapeutic substance reservoir is carried in the housing. 16. A device according to claim 1, wherein the permanent magnet solenoid pump is about 5% to about 10% efficient in terms of electrical energy input and fluid work output. 17. A device according to claim 1, wherein the permanent magnet solenoid pump occupies a total volume of less than about 0.5 cubic centimeters. 18. An implantable therapeutic substance delivery device comprising: a housing; a therapeutic substance reservoir; a power source carried in the housing; electronics carried in the housing, the electronics coupled to the power source; and, a permanent magnet solenoid pump carried in the housing and coupled to the electronics, the permanent magnet solenoid pump configured for pumping a therapeutic substance from the therapeutic substance reservoir through an infusion outlet, wherein the permanent magnet solenoid pump comprises: a pump piston movable within a pump cylinder, a permanent magnet carried on the pump piston; a first coil formed around the pump cylinder and positioned adjacent a first pole of the permanent magnet; a second coil formed around the pump cylinder and positioned adjacent a second pole of the permanent magnet; a pumping chamber proximate the infusion outlet; an inlet valve through which therapeutic substance passes into the pumping chamber; and an outlet valve through which therapeutic substance passes into the infusion outlet from the pumping chamber; a biasing element biasing the pump piston towards the inlet valve, wherein the biasing element provides a biasing force sufficient to overcome frictional losses during movement of the pump piston within the pump cylinder, open the outlet valve of the pumping chamber, open the inlet valve of the pumping chamber, and overcome pressure losses between the infusion outlet and an infusion site to which the therapeutic substance is to be delivered. 19. A device according to claim 18, wherein the inlet valve is sealed when the biasing element biases the pump piston against the inlet valve. 20. A device according to claim 18, wherein the biasing element biases the pump cylinder towards the infusion outlet. 21. A device according to claim 18, wherein the biasing element exerts substantially the sole force on the pump piston to expulse therapeutic substance through the infusion outlet. 22. A device according to claim 18, wherein the non-magnetic biasing element comprises a mechanical spring. 23. A device according to claim 18, wherein the biasing element is located proximate an end of the pump cylinder that is opposite from the infusion outlet. 24. A device according to claim 18, wherein the inlet valve is carried on an end of the pump cylinder. 25. A device according to claim 18, wherein the biasing element is located proximate a first end of the pump piston and the pumping chamber is located proximate a second end of the pump piston. 26. A device according to claim 18, wherein the permanent magnet solenoid pump comprises a therapeutic substance flow path tat is composed of therapeutic substance compatible material. 27. A device according to claim 18, wherein the permanent magnet solenoid pump comprises N coils formed around the pump cylinder and N-1 permanent magnets carried on the pump piston, wherein N is an integer in the range from 3 to 10. 28. A device according to claim 18, wherein the therapeutic substance reservoir is located outside of the housing. 29. A device according to claim 18, wherein the therapeutic substance reservoir is carried in the housing. 30. A device according to claim 18, wherein the permanent magnet solenoid pump is about 5% to about 10% efficient in terms of electrical energy input and fluid work output. 31. A device according to claim 18, wherein the permanent magnet solenoid pump occupies a total volume of less than about 0.5 cubic centimeters.
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