|국가/구분||United States(US) Patent 등록|
|국제특허분류(IPC7판)||C07C-045/00 C07C-049/115 C07C-049/00 C07D-311/78 C07D-311/00 C07D-315/00 A61K-031/00|
|미국특허분류(USC)||568/311; 568/327; 549/381; 549/416; 514/681; 514/732; 514/738|
|발명자 / 주소|
|출원인 / 주소|
|대리인 / 주소||
|인용정보||피인용 횟수 : 1 인용 특허 : 9|
The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
What is claimed is: 1. A compound according to formula (I) or (II): wherein in formula (I), A1 is selected from hydrogen,--COOH and the group consisting of: in formula (I), when A1 is hydrogen, A2 is selected from the group consisting of: in formula (I), when A1 is other than hydrogen, A2 is selected from the group consisting of: in formula (II), A1 is hydrogen or--COOCH3, and A3 is--OAc; wherein each R2 is independently galloyl, or a salt of said compound. 2. The compound according to claim 1 that is 3. The compound according to clai...