초록 ▼

A nasal delivery device is provided for delivering substances such as liquid drugs, vaccines and the like to a nasal passage. The nasal delivery device preferably comprises a drug container such as syringe and a separable spray nozzle. The spray nozzle includes a rigid plastic cap having a spray ap

A nasal delivery device is provided for delivering substances such as liquid drugs, vaccines and the like to a nasal passage. The nasal delivery device preferably comprises a drug container such as syringe and a separable spray nozzle. The spray nozzle includes a rigid plastic cap having a spray aperture at a distal end of the nozzle for delivering the liquid substance to the nasal passage. Attachment means is provided for attaching the spray nozzle to the syringe at the time of the delivery of the liquid substance to the nasal passage. The nozzle defines a conduit that allows fluid communication from the syringe to the spray aperture. The nozzle includes an internal valve between the spray aperture and the syringe for allowing only pressurized liquid substance to flow through the conduit and the aperture so that a mist or spray is delivered through the spray aperture.

대표청구항 ▼

What is claimed is: 1. A nasal delivery device for delivering liquid substances including drug and vaccines to a nasal passage, comprising: a syringe having a rigid body with an outlet opening at one end; a separate spray nozzle including: a rigid cap body having an internal passage extending betwe

What is claimed is: 1. A nasal delivery device for delivering liquid substances including drug and vaccines to a nasal passage, comprising: a syringe having a rigid body with an outlet opening at one end; a separate spray nozzle including: a rigid cap body having an internal passage extending between an inlet opening at one end and a spray aperture at a distal end, said cap body being sealingly secured to the syringe body adjacent the outlet opening; and a valve having a skirt portion surrounding a base, the skirt portion movable from a first position in contact with an internal wall of the internal passage to a second position spaced from the internal wall of the internal passage when substances pressurized at or above a minimum threshold pressure flows from the inlet opening, so that only pressurized substances at or above the minimum pressure threshold level flow through the passage into and out of the spray aperture and so that substances below the minimum threshold pressure are prevented from flowing through the spray aperture, wherein the valve is configured to operate in two directions and wherein the valve defines at least one passage through the skirt portion allowing fluid to be drawn through the valve and into the syringe. 2. The device of claim 1, wherein the syringe includes a groove formed on an exterior surface near the outlet opening and the cap body includes a corresponding projection in the inlet opening that is at least partially received by the groove. 3. The device of claim 2, wherein the projection is sufficiently rigid such that the cap body is fixedly secured to the syringe when the projection is received by the groove precluding subsequent removal of the spray nozzle. 4. The device of claim 1, wherein the cap includes a radially outward projecting flange for preventing over-insertion of the nozzle into the nasal passage. 5. The device of claim 1, whereupon the syringe includes an elongated barrel that defines a chamber and said chamber prefilled with at least one substance to be nasally delivered.