IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0135316
(2002-04-29)
|
등록번호 |
US-7300457
(2007-11-27)
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발명자
/ 주소 |
|
출원인 / 주소 |
- Advanced Bio Prosthetic Surfaces, Ltd.
|
대리인 / 주소 |
Rosenbaum & Associates, PC
|
인용정보 |
피인용 횟수 :
131 인용 특허 :
139 |
초록
▼
Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of the graft. The implantable graft
Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of the graft. The implantable graft is preferably fabricated by vacuum deposition of metallic and/or pseudometallic materials into either single or multi-layered structures with the plurality of microperforations either being formed during deposition or after deposition by selective removal of sections of the deposited film. The implantable medical grafts are suitable for use as endoluminal or surgical grafts and may be used as vascular grafts, stent-grafts, skin grafts, shunts, bone grafts, surgical patches, non-vascular conduits, valvular leaflets, filters, occlusion membranes, artificial sphincters, tendons and ligaments.
대표청구항
▼
What is claimed is: 1. An implantable medical graft, comprising: a. a tubular graft member comprising a vacuum deposited metal film having a first surface, a second surface and a thickness intermediate the first surface and the second surface wherein said thickness is less than 75 μm; and b. a
What is claimed is: 1. An implantable medical graft, comprising: a. a tubular graft member comprising a vacuum deposited metal film having a first surface, a second surface and a thickness intermediate the first surface and the second surface wherein said thickness is less than 75 μm; and b. a plurality of microperforations formed in and passing through the thickness of the vacuum deposited metal film and communicating between the first surface and the second surface. 2. The implantable medical graft according to claim 1, wherein the vacuum deposited metal film is made of a metallic material selected from the group consisting of titanium, vanadium, aluminum, nickel, tantalum, zirconium, chromium, silver, gold, silicon, magnesium, niobium, scandium, platinum, cobalt, palladium, manganese, molybdenum and alloys thereof. 3. The implantable graft according to claim 1, wherein the each of the plurality of microperforations is capable of undergoing geometric deformation. 4. The implantable graft according to claim 1, wherein the plurality of microperforations are arrayed in at least one pattern that imparts at least one of compliance and pliability to the body member. 5. The implantable graft according to claim 1, wherein the plurality of microperforations is arrayed in at least one pattern sufficient to permit dimensional change of at least a portion of the device. 6. The implantable graft according to claim 5, wherein the dimensional change comprises at elastic one of elastic, plastic, shape memory and superelastic compliance. 7. The implantable medical graft according to claim 1, wherein the tubular graft member further comprises a first surface including a luminal surface and a second surface including an abluminal surface. 8. The implantable medical graft according to claim 1, wherein the tubular graft member further comprises a generally planar member. 9. The implantable medical graft according to claim 1, wherein the plurality of microperforations each further comprise a generally co-planar tri-leg configuration. 10. An implantable medical device, comprising a generally tubular, non-coiled, graft member consisting essentially of: a. a vacuum deposited metal film having a first surface, a second surface and a thickness intermediate the first surface and the second surface wherein said thickness is less than 75 μm; and b. a plurality of microperforations formed in and passing through the thickness of the vacuum deposited metal film and communication between the first surface and the second surface, each of the plurality of microperforations having an open surface area less than about 2 mm2 when the graft member is in a non-diametrically enlarged state. 11. The implantable medical graft according to claim 10, wherein the vacuum deposited metal film is made of a metallic material selected from the group consisting of titanium, vanadium, aluminum, nickel, tantalum, zirconium, chromium, silver, gold, silicon, magnesium, niobium, scandium, platinum, cobalt, palladium, manganese, molybdenum and alloys thereof. 12. The implantable graft according to claim 10, wherein the each of the plurality of microperforations is capable of undergoing geometric deformation. 13. The implantable graft according to claim 10, wherein the plurality of microperforations are arrayed in at least one pattern that imparts at least one of compliance and pliability to the body member. 14. The implantable graft according to claim 10, wherein the plurality of microperforations is arrayed in at least one pattern sufficient to permit dimensional change of at least a portion of the device. 15. The implantable graft according to claim 14, wherein the dimensional change comprises at elastic one of elastic, plastic, shape memory and superelastic compliance. 16. The implantable medical graft according to claim 10, wherein the tubular graft member further comprises a first surface including a luminal surface and a second surface including an abluminal surface. 17. The implantable medical graft according to claim 10, wherein the tubular graft member further comprises a generally planar member. 18. The implantable medical graft according to claim 10, wherein the plurality of microperforations each further comprise a generally co-planar tri-leg configuration.
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