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Unit dose capsules for use in a dry powder inhaler 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61M-015/00
출원번호 US-0621092 (2000-07-21)
등록번호 US-7305986 (2007-12-11)
발명자 / 주소
  • Steiner,Solomon S.
  • Feldstein,Robert
  • Fog,Per B.
  • Poole,Trent
출원인 / 주소
  • MannKind Corporation
대리인 / 주소
    Pabst Patent Group LLP
인용정보 피인용 횟수 : 74  인용 특허 : 23

초록

Described are capsules to contain a drug for use in an inhaler. The capsules may be two-part capsules where each half has apertures which may correspond to apertures in the other half. The first half fits snugly within the second half and the two halves may be rotated around their longitudinal axes

대표청구항

What is claimed is: 1. A capsule to contain drug for use in an inhaler comprising at least one keying surface on an outside surface of a distal end of the capsule that is adapted to orient the capsule within the inhaler or identifies the drug to be placed in the capsule and at least one hole allowi

이 특허에 인용된 특허 (23)

  1. Clark, Andrew; Foulds, George H., Aerosolized active agent delivery.
  2. Kriesel Marshall S. (Saint Paul MN) Thompson Thomas (Richfield MN), Closed drug delivery system.
  3. Keritsis Gus D. (Richmond VA), Container for additive materials for smoking articles.
  4. Keritsis Gus D. (Richmond VA), Container for additive materials for smoking articles.
  5. Haber Terry M. (Lake Forest CA) Smedley William H. (Lake Elsinor CA) Foster Clark B. (Laguna Niguel CA), Controlled multi-pharmaceutical inhaler.
  6. Valentini Luigi (Milan ITX) Ceschel Giancarlo (Milan ITX), Disposable inhaler with pre-pierced capsule.
  7. Stimpson Philip G. (Welford GBX), Drug dispensing system.
  8. Yang Joo H. (Seoul KRX), Empty medicinal and food capsule.
  9. Kreamer Jeffry W., Indicator for a medicament inhaler.
  10. Kulessa Gerhard (Stollberg DT) Mommertz Elmar (Laurentsberg near Aachen DT), Inhalator for agglomeratable pulverulent solids.
  11. Cook Robert Stanley,GBX ; Hobbs Michael Anthony,GBX ; Leighton Ann-Marie,GBX ; Simpkin Gordon Thomas,GBX ; Trunley Roy,GBX, Inhaler.
  12. Grayson Robert E. (Rte. 2 S. Box 2186 Great Falls MT 59401), Locking capsule.
  13. Schwarz Erwin (Eberbach ; Baden DT), Locking hard gelatin capsule.
  14. Casper Robert A. (Raleigh NC) McCartney Michael L. (Durham NC) Jochem Warren J. (Cary NC) Parr Alan F. (Cary NC), Medical capsule device actuated by radio-frequency (RF) signal.
  15. Zoltan Bart J. (Old Tappan NJ) Laube Beth L. (Baltimore MD) Adams ; III George K. (Baltimore MD) Bow Clark F. (Newton NJ) Devito Ralph J. (Stanhope NJ) Harrington Walter (Flanders NJ) Hoffman Louis S, Medication delivery system phase two.
  16. Kim Myung K. (Seoul KRX), Medicinal capsule.
  17. Schultz Robert ; Witham Clyde ; Hill Malcolm, Methods of dry powder inhalation.
  18. Sayer William J. (1618 Willow Rd. Palo Alto CA 94304), Mouthpiece with a tongue retractor.
  19. Hobbs Michael A.,GBX ; Calvert John R.,GBX ; Cook Robert S.,GBX ; Trunley Roy,GBX ; Simpkin Gordon T.,GBX, Multi dose inhaler apparatus.
  20. LeBlond J. Paul (Burnaby CAX), Personal repellent device.
  21. Clarke Alastair Robert,GBX ; Sleath Clive,GBX ; Shepherd Michael Trevor,GBX, Powder inhaler with breath flow regulation valve.
  22. Clarke Alastair Robert,GBX ; Sleath Clive,GBX ; Shepherd Michael Trevor,GBX, Powder inhaler with breath flow regulation valve.
  23. Schuler, Carlos; Paboojian, Steve; Tuttle, Derrick J.; Smith, Adrian E.; Rasmussen, Dennis R.; Bakshi, Aneesh; Clark, Andrew; Ward, Brian R. S.; Alston, Jr., William W.; Nason, Kevin S., Systems and methods for aerosolizing pharmaceutical formulations.

이 특허를 인용한 특허 (74)

  1. Adamo, Benoit; Polidoro, John M.; Overfield, Dennis; Sahi, Carl R.; Laurenzi, Brendan; Smutney, Chad C.; Kinsey, P. Spencer, Apparatus and method for simulating inhalation efforts.
  2. Adamo, Benoit; Polidoro, John M.; Overfield, Dennis; Sahi, Carl R.; Laurenzi, Brendan; Smutney, Chad C.; Kinsey, Spencer P., Apparatus and method for simulating inhalation efforts.
  3. Adamo, Benoit; McLean, Scott; Smutney, Chad C.; Polidoro, John M.; Sahi, Carl R., Apparatus, system and method for measuring resistance of an inhaler.
  4. Adamo, Benoit; McLean, Scott; Smutney, Chad C.; Polidoro, John M.; Sahi, Carl R., Apparatus, system and method for measuring resistance of an inhaler.
  5. Adamo, Benoit; McLean, Scott; Smutney, Chad C.; Polidoro, John M.; Sahi, Carl R., Apparatus, system and method for measuring resistance of an inhaler.
  6. Stevenson, John J.; Moye-Sherman, Destardi, Catalysis of diketopiperazine synthesis.
  7. Stevenson, John J.; Moye-Sherman, Destardi, Catalysis of diketopiperazine synthesis.
  8. Pruiett, Jason W., Container and cap assembly.
  9. Seeney, Philip; Jennings, Douglas Ivan, Delivery devices.
  10. Seeney, Philip; Jennings, Douglas Ivan, Delivery devices.
  11. Richardson, Peter; Baughman, Robert A.; Leone-Bay, Andrea; Costello, Donald, Delivery of active agents.
  12. Grant, Marshall L.; Stowell, Grayson W.; Menkin, Paul, Diketopiperazine microparticles with defined specific surface areas.
  13. Grant, Marshall L.; Stowell, Grayson W.; Menkin, Paul, Diketopiperazine microparticles with defined specific surface areas.
  14. Leone-Bay, Andrea; Moye-Sherman, Destardi; Wilson, Bryan R., Diketopiperazine salts for drug delivery and related methods.
  15. Leone-Bay, Andrea; Moye-Sherman, Destardi; Wilson, Bryan R., Diketopiperazine salts for drug delivery and related methods.
  16. Jones, Andrew; Miller, Richard L., Dose delivery device for inhalation with first and second portions to open a dose chamber.
  17. Smutney, Chad C.; Adamo, Benoit; Polidoro, John M.; Kinsey, P. Spencer; Overfield, Dennis; Sahi, Carl R.; Billings, Christine; Marino, Mark T., Dry powder drug delivery system.
  18. Smutney, Chad C.; Adamo, Benoit; Polidoro, John M.; Kinsey, P. Spencer; Overfield, Dennis; Sahi, Carl R.; Billings, Christine; Marino, Mark T., Dry powder drug delivery system.
  19. Smutney, Chad C.; Adamo, Benoit; Laurenzi, Brendan F.; Kinsey, P. Spencer, Dry powder drug delivery system and methods.
  20. Smutney, Chad C.; Adamo, Benoit; Polidoro, John M.; Kinsey, P. Spencer; Overfield, Dennis; Sahi, Carl; Billings, Christine; Marino, Mark T., Dry powder drug delivery system and methods.
  21. Smutney, Chad C.; Adamo, Benoit; Polidoro, John M.; Kinsey, P. Spencer; Overfield, Dennis; Sahi, Carl; Billings, Christine; Marino, Mark T., Dry powder drug delivery system and methods.
  22. Dunne, Stephen T., Dry powder inhaler.
  23. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
  24. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
  25. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
  26. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony; He, Tom; Mann, Alfred, Dry powder inhaler and system for drug delivery.
  27. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
  28. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
  29. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
  30. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfiled, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
  31. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfileld, Dennis; Bryant, Anthony; He, Tom; Mann, Alfred, Dry powder inhaler and system for drug delivery.
  32. Denny, John; King, Michael; Lopath, Patrick D.; Warden, Jeffrey Alan, Dry powder inhalers.
  33. Fabio, Karine; Guarneri, Joseph J.; Curley, Kieran; Grant, Marshall L.; Leone-Bay, Andrea, Heat-stable dry powder pharmaceutical compositions and methods.
  34. Grant, Marshall; Menkin, Paul; Stowell, Grayson W., High capacity diketopiperazine microparticles and methods.
  35. Grant, Marshall; Menkin, Paul; Stowell, Grayson W., High capacity diketopiperazine microparticles and methods.
  36. Hokenson, Mark; Oberg, Keith A., Increasing drug affinity for crystalline microparticle surfaces.
  37. Smutney, Chad C.; Leone-Bay, Andrea; Galarza, Jose M.; Munoz, Hector; Martin, George R.; Grant, Marshall L., Inhalable vaccine compositions and methods.
  38. Poole, Trent; Steiner, Solomon S., Inhalation apparatus.
  39. Trent, Poole; Steiner, Solomon S., Inhalation apparatus.
  40. Kreutzmann, Vera; Rosenbeiger, Sven; Mornhinweg, Markus; Kummer, Frank; Selzer, Titus, Inhalation therapy device comprising a valve.
  41. Dunne, Stephen Terence; Besseler, Jens; Frentzel-Beyme, Jessica; Holakovsky, Holger; Kladders, Heinrich; Weiler, Claudius; Zumblick, Ole, Inhalator and capsule for an inhalator.
  42. Adamo, Benoit; Shah, Saiyam; Smutney, Chad C., Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution.
  43. Kinsey, P. Spencer; Adamo, Benoit, Inhaler device.
  44. Overfield, Dennis; Sahi, Carl R.; Adamo, Benoit; Kinsey, P. Spencer; McLean, Scott; Polidoro, John M.; Smutney, Chad C., Interactive apparatus and method for real-time profiling of inhalation efforts.
  45. Adamo, Benoit; Shah, Saiyam; Smutney, Chad C., Laser diffraction with inhaler enclosed in positive pressure chamber.
  46. Boyes, Robert Nichol; Braithwaite, Philip Wilson, Medicament unit dose cartridge and delivery device.
  47. Leone-Bay, Andrea; Stowell, Grayson W.; Guarneri, Joseph J.; Carlson, Dawn M.; Grant, Marshall; Smutney, Chad C., Method and composition for treating migraines.
  48. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
  49. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
  50. Hokenson, Mark; Oberg, Keith A., Method of drug formulation.
  51. Hokenson, Mark; Oberg, Keith A., Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces.
  52. Hokenson, Mark; Oberg, Keith A., Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces.
  53. Oberg, Keith A.; Sulner, Joseph; Grant, Marshall L., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
  54. Oberg, Keith A.; Sulner, Joseph; Grant, Marshall L., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
  55. Richardson, Peter; Baughman, Robert A.; Costello, Donald, Method of preventing adverse effects by GLP-1.
  56. Richardson, Peter; Baughman, Robert A.; Potocka, Elizabeth; Boss, Anders Hasager; Petrucci, Richard, Method of treating diabetes type 2 by administering ultrarapid acting insulin.
  57. Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Methods and compositions for delivering peptides.
  58. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
  59. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
  60. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
  61. Boss, Anders Hasager; Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Potentiation of glucose elimination.
  62. Boss, Anders Hasager; Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Potentiation of glucose elimination.
  63. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  64. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  65. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  66. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  67. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  68. Denny, John; King, Michael; Lopath, Patrick D.; Warden, Jeffrey Alan, Tubular dry powder drug containment systems, associated inhalers and methods.
  69. Steiner, Solomon S.; Feldstein, Robert; Fog, Per B.; Poole, Trent A., Unit dose capsules and dry powder inhaler.
  70. Steiner, Solomon S.; Feldstein, Robert; Fog, Per B.; Poole, Trent A., Unit dose capsules and dry powder inhaler.
  71. Steiner, Solomon S.; Fog, Per B.; Poole, Trent; Feldstein, Robert, Unit dose capsules and dry powder inhaler.
  72. Steiner, Solomon S.; Fog, Per B.; Poole, Trent; Feldstein, Robert, Unit dose capsules and dry powder inhaler.
  73. Steiner, Solomon S.; Poole, Trent A.; Fog, Per B.; Pohl, Roderike; Crick, Michael; Feldstein, Robert, Unit dose cartridge and dry powder inhaler.
  74. Richardson, Peter; Baughman, Robert A.; Potocka, Elizabeth; Boss, Anders Hasager; Petrucci, Richard, Use of ultrarapid acting insulin.
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