초록 ▼

A system for filtering and processing blood that is simple to implement and that reduces the need for human intervention. The system may be used to collect red blood cells (RBCs). For such a system, a disposable set may be provided with an inlet port, an RBC container, a centrifuge rotor having a va

A system for filtering and processing blood that is simple to implement and that reduces the need for human intervention. The system may be used to collect red blood cells (RBCs). For such a system, a disposable set may be provided with an inlet port, an RBC container, a centrifuge rotor having a variable total volume, and a filter, along with tubing connecting the port, the container, the rotor and the filter. The filter is located in tubing between the inlet port and the rotor. A control unit is also provided and includes a spinner in which the rotor may be held, a flow-control arrangement for controlling flow among the various components of the disposable set, and an electronic controller. The whole blood is directed by the flow-control arrangement from the inlet through the filter to the rotor. The rotor includes an elastic diaphragm, and the control unit's flow-control arrangement includes a pump or other device for applying a positive and negative pressure to the rotor's elastic diaphragm. The spinner rotates the rotor so as to separate the whole blood into plasma and RBCs. Preferably, the plasma is urged out of the rotor first and returned to the donor, while the rotor is still being spun. After the plasma has been removed from the rotor, the RBCs are urged from the rotor to an RBC container. In preferred embodiments, the filter is a white blood cell filter, so that white blood cells are filtered from the blood before it reaches the rotor.

대표청구항 ▼

What is claimed is: 1. A system for processing blood, the system comprising: a disposable set having a port for permitting the introduction of blood from a whole blood source into the disposable set, a variable-volume centrifuge rotor wherein the whole blood is separated into components, a filter t

What is claimed is: 1. A system for processing blood, the system comprising: a disposable set having a port for permitting the introduction of blood from a whole blood source into the disposable set, a variable-volume centrifuge rotor wherein the whole blood is separated into components, a filter that is located in a fluid path between the port and rotor, and a blood-component container for storing a separated blood component, the blood-component container being in fluid communication with the rotor; and a control unit having a flow-control arrangement which urges a blood component from the rotor to the blood-component container after the blood has been separated, the control unit further including means for spinning the rotor and for varying the volume of the rotor. 2. The system according to claim 1, wherein the centrifuge rotor includes an elastic diaphragm which defines the volume of the rotor, and wherein the control unit includes means for varying gas pressure adjacent the elastic diaphragm. 3. The system according to claim 2, wherein the means for varying gas pressure includes means for applying a vacuum to the elastic diaphragm, so as to draw blood into the rotor. 4. The system according to claim 1, wherein the filter is capable of filtering white blood cells from whole blood passing through the filter. 5. A system for collecting red blood cells from a donor, the system comprising: a disposable set having a port for permitting the introduction of blood from the donor into the disposable set; a centrifuge rotor having a variable total volume; a filter that is located in a fluid path between the port and rotor; return means for permitting return of plasma to the donor, the return means being in fluid communication with the centrifuge rotor; and an RBC container in fluid communication with the centrifuge rotor; and a control unit having a spinner that holds the rotor, the spinner being able to spin the rotor so as to separate blood into blood components; and a flow-control arrangement which urges a blood component from the rotor while the rotor is being spun. 6. The system according to claim 5, wherein the control unit further includes means for varying the volume of the rotor. 7. The system according to claim 6, wherein the centrifuge rotor includes an elastic diaphragm which defines the volume of the rotor, and wherein the control unit includes means for varying gas pressure adjacent the elastic diaphragm. 8. The system according to claim 7, wherein the means for varying gas pressure includes means for applying a vacuum to the elastic diaphragm, so as to draw blood into the rotor. 9. The system according to claim 7, wherein the filter is capable of filtering white blood cells from whole blood passing through the filter. 10. The system according to claim 5, wherein the return means includes a temporary storage container.