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특허 상세정보

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내보내기 페이스북 공유 카카오톡 공유

Method of treating secretory diarrhea with enteric formulations of proanthocyanidin polymer

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A01N-065/00   
미국특허분류(USC) 424/725; 514/183; 514/732; 514/867
출원번호 US-0712033 (2000-11-14)
등록번호 US-7341744 (2008-03-11)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    King & Spalding, LLP
인용정보 피인용 횟수 : 37  인용 특허 : 5
초록
▼

Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from a Croton spp. or a Calophyllum spp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations w...

대표
청구항
▼

What is claimed is: 1. A method of treatment for secretory diarrhea in animals, including humans, said method comprising: administering, via the oral route of administration to a non-human animal selected from the group consisting of bovine, ovine, swine, poultry, equine, canine and feline animals or a human suffering from secretory diarrhea, a dosage of from 0.1 to 100 mg/kg/day of a pharmaceutical composition comprising an aqueous soluble proanthocyanidin polymer composition isolated from a Croton species or a Calophyllum species, said aqueous soluble...

이 특허에 인용된 특허 (5)

  1. Virdalm Carl A. (Starevagen 10 872 00 Kramfors SEX). Method for suppressing states of illness in the digestive system. USP1989084857327.
  2. Masquelier Jack (Parc des Tourelles FRX). Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof. USP1987104698360.
  3. Tempesta Michael S. (Moss Beach CA). Proanthocyanidin polymers having antiviral activity and methods of obtaining same. USP1993055211944.
  4. Wrsch Pierre (La Tour-De-Peil CHX). Treatment of diarrhoea with compositions derived from carob pod. USP1991085043160.
  5. Welsh Michael J. (Riverside IA) Sheppard David N. (Coralville IA). Use of sulfonylureas and other potassium channel regulators to treat secretory diarrhea. USP1993085234922.

이 특허를 인용한 특허 피인용횟수: 37

  1. Huang, Alexander L.; Wu, Gin. Antibacterial having an extract of pomegranate combined with hydrogen peroxide. USP2014058734867.
  2. Quart, Barry D.. Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer. USP2018069987250.
  3. Quart, Barry D.. Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer. USP2014108852649.
  4. Rozhon, Edward James; Khandwala, Atul S.; Sabouni, Akram; Balwani, Gul P.; Chan, Jody Wai-Han; Sesin, David F.. Compositions and methods of treatment with proanthocyanidin polymer antidiarrheal compositions. USP2013118574634.
  5. Jones, Graham Peter; Doyle, Kevin James. Compounds, compositions and methods comprising isoxazole derivatives. USP2012088236838.
  6. Jones, Graham Peter; Doyle, Kevin James. Compounds, compositions and methods comprising oxadiazole derivatives. USP2012068207205.
  7. Jones, Graham Peter; Doyle, Kevin James. Compounds, compositions and methods comprising oxadiazole derivatives. USP2014088796321.
  8. Penrose, Stephen David; Doyle, Kevin James. Compounds, compositions and methods comprising pyrazole derivatives. USP2013018343976.
  9. Quart, Barry D.; Rosenbaum, David P.. Method for treatment of constipation-predominant irritable bowel syndrome. USP2015099138450.
  10. Quart, Barry D.; Rosenbaum, David; Neenan, Thomas; Blanks, Robert C.. Method for treatment of diarrhea-predominant irritable bowel syndrome. USP2018059980938.
  11. Huang, Alexander L; Wu, Gin. Method of killing a bacteria with a plant-based biocidal solution. USP2017059636361.
  12. Huang, Alexander L.; Wu, Gin. Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide. USP2015119192635.
  13. Forbes, William; Bortey, Enoch; King, Steven; Chaturvedi, Pravin. Methods and compositions for treating HIV-associated diarrhea. USP2017039585868.
  14. Forbes, William; Bortey, Enoch; King, Steven; Chaturvedi, Pravin. Methods and compositions for treating HIV-associated diarrhea. USP2015028962680.
  15. Huang, Alexander L; Wu, Gin. Methods of inhibiting a bacterial virulence in a subject. USP2017039603883.
  16. Huang, Alexander L; Wu, Gin. Methods of treating a gastrointestinal spasm associated with chemotherapy or radiation therapy. USP2016089408869.
  17. Huang, Alexander L; Wu, Gin. Methods of treating a treatment-resistant gastrointestinal spasm. USP2018039907818.
  18. Huang, Alexander L; Wu, Gin. Methods of treating a treatment-resistant gastrointestinal spasm with an oxidized tannin. USP20180810039784.
  19. Huang, Alexander L; Wu, Gin. Methods of treating drug side-effects that include a gastrointestinal spasm. USP2015079089596.
  20. Huang, Alexander L; Wu, Gin. Methods of treating gastroesophageal reflux disease. USP2017039603871.
  21. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms. USP2014058716351.
  22. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms in a subject having Crohn's Disease or ulcerative colitis. USP2014058716353.
  23. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms in a subject having colorectal cancer. USP2014078772352.
  24. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms in a subject having diverticulitis. USP2014078772350.
  25. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms triggered by stress. USP2014088809399.
  26. Huang, Alexander L; Wu, Gin. Methods of treating malnutrition. USP2015028946304.
  27. Huang, Alexander L; Wu, Gin. Methods of treating necrotic enteritis. USP2015059023895.
  28. Huang, Alexander L.; Wu, Gin. Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. USP2014058722040.
  29. Huang, Alexander L; Wu, Gin. Tannin formulation for treating GI spasms. USP2014058716352.
  30. Huang, Alexander L; Wu, Gin. Tannin formulation for treating GI spasms in a subject having Crohn's disease or ulcerative colitis. USP2014078765818.
  31. Huang, Alexander L; Wu, Gin. Tannin formulation for treating gastrointestinal spasms in a subject having colorectal cancer. USP2014098822544.
  32. Huang, Alexander L; Wu, Gin. Tannin formulation for treating gastrointestinal spasms in a subject having diverticulitis. USP2014078772351.
  33. Huang, Alexander L; Wu, Gin. Tannin formulation for treating gastrointestinal spasms triggered by stress. USP2014098822545.
  34. Huang, Alexander L; Wu, Gin. Tannin formulation for treating malnutrition. USP2015028952072.
  35. Huang, Alexander L.; Wu, Gin. Therapeutic composition produced using punica granatum and hydrogen peroxide. USP2013018343552.
  36. Huang, Alexander L.; Wu, Gin. Treating a bacteria-induced gastric disorder with a mixture having pomegranate and hydrogen peroxide. USP2014058722116.
  37. Huang, Alexander L; Wu, Gin. Treating inflammation with a binding system. USP2014078790640.

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