Method and apparatus for determining cardiac output
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/08
A61B-005/02
출원번호
US-0763971
(2004-01-23)
등록번호
US-7367954
(2008-05-06)
발명자
/ 주소
Starr,Eric W
Pennock,Bernard
Kandis,Mouhyieldin
출원인 / 주소
RIC Investments, LLC
대리인 / 주소
Haas,Michael W.
인용정보
피인용 횟수 :
15인용 특허 :
29
초록▼
A method and apparatus for use in determining the cardiac output. The method includes measuring a first parameter indicative of a patient's oxygen uptake and a second parameter indicative of the patient's fractional arterial oxygen concentration. The method also includes inducing a change in the pa
A method and apparatus for use in determining the cardiac output. The method includes measuring a first parameter indicative of a patient's oxygen uptake and a second parameter indicative of the patient's fractional arterial oxygen concentration. The method also includes inducing a change in the patient's arterial oxygen concentration while taking these measurements to monitor the effects of the change in the patient's arterial oxygen concentration. The cardiac output is determined from the data collected regarding the effects of the change in the patient's arterial oxygen concentration.
대표청구항▼
What is claimed is: 1. An apparatus for measuring cardiac output comprising: means for measuring a first parameter indicative of a patient's oxygen uptake; means for measuring a second parameter indicative of such a patient's fractional arterial oxygen concentration; means for inducing a change in
What is claimed is: 1. An apparatus for measuring cardiac output comprising: means for measuring a first parameter indicative of a patient's oxygen uptake; means for measuring a second parameter indicative of such a patient's fractional arterial oxygen concentration; means for inducing a change in such a patient's arterial oxygen concentration; a processor adapted to determine an estimate of such a patient's cardiac output based on the output of the first parameter and the second parameter; and outputting means for outputting a result indicative of such a patient's cardiac output. 2. The apparatus according to claim 1, wherein the means for measuring the second parameter is a pulse oximetry system including a pulse oximeter sensor in contact with such a patient. 3. The apparatus according to claim 1, wherein the second parameter indicative of fractional arterial oxygen concentration is one of SaO2, PaO2, CaO2 or SpO2. 4. The apparatus according to claim 1, wherein the patient flow measuring system includes a flow sensor operatively coupled to such a patient's airway such that gas inhaled and exhaled by the patient passes through the flow sensor. 5. The apparatus according to claim 1, wherein the oxygen analyzing system includes an oxygen analyzing element comprising (a) an airway adapter having an optical window and (b) an oxygen transducer having an photoemitter and a photodetector, and wherein the oxygen analyzing element is disposed proximate to such a patient's airway such that gas inhaled and exhaled by such a patient passes in front of the optical window. 6. The apparatus according to claim 1, wherein the means for inducing a change in such a patient's arterial oxygen concentration comprises a system for introducing a non-oxygen breathing gas into a stream of gas to be inhaled by such a patient or a system for introducing oxygen into the stream of gas to be inhaled by such a patient. 7. The apparatus according to claim 1, wherein the means for inducing a change in such a patient's arterial oxygen concentration comprises a rebreathing system for causing such a patient to rebreathe gas exhaled by such a patient. 8. The apparatus according to claim 7, wherein the rebreathing system further comprises means for removing carbon dioxide CO2 from the exhaled gas before the exhaled gas is rebreathed. 9. The apparatus according to claim 1, wherein the processor determines: (a) a deviation of such a patient's oxygen uptake from a baseline oxygen uptake level occurring responsive to an induced a change in such a patient's arterial oxygen concentration; (b) a deviation of such a patient's arterial oxygen concentration from a baseline arterial oxygen concentration level occurring responsive to an induced a change in such a patient's arterial oxygen concentration; and (c) a comparison of the deviation in oxygen uptake to the deviation in arterial oxygen concentration. 10. The apparatus according to claim 9, wherein the processor determines the deviation of such a patient's oxygen uptake by determining an effective area between the baseline oxygen uptake level and an oxygen uptake curve occurring responsive to the induced change in such a patient's arterial oxygen concentration, and determines a deviation of such a patient's arterial oxygen concentration by determining an effective area between the baseline arterial oxygen concentration level and an arterial oxygen concentration curve occurring responsive to the induced change in such a patient's arterial oxygen concentration. 11. The apparatus according to claim 9, wherein the processor determines the deviation of such a patient's oxygen uptake by determining a slope of a line extending between the baseline oxygen uptake level and a point on an oxygen uptake curve occurring responsive to the induced change in such a patient's arterial oxygen concentration, and determines the deviation of such a patient's arterial oxygen concentration by determining a slope of a line extending between the baseline arterial oxygen concentration level and a point on an arterial oxygen concentration curve occurring responsive to the induced change in such a patient's arterial oxygen concentration. 12. The apparatus according to claim 9, wherein the processor determines the deviation of such a patient's oxygen uptake by determining a magnitude between the baseline oxygen uptake level and a point on an oxygen uptake curve occurring responsive to the induced change in such a patient's arterial oxygen concentration, and determines the deviation of such a patient's arterial oxygen concentration by determining a magnitude between the baseline arterial oxygen concentration level and a point on an arterial oxygen concentration curve occurring responsive to the induced change in such a patient's arterial oxygen concentration. 13. A method for measuring cardiac output comprising: (1) measuring a first parameter indicative of a patient's oxygen uptake and a second parameter indicative of such a patient's fractional arterial oxygen concentration; (2) inducing a change in such a patient's arterial oxygen concentration; (3) repeating the first parameter and the second parameter measurements set forth in step (1); and (4) determining an estimate of the patient's cardiac output based on the first parameter and the second parameter information collected in steps (1) and (3). 14. The method according to claim 1, wherein the second parameter indicative of fractional arterial oxygen concentration is one of SaO2, PaO2, CaO2 or SpO2. 15. The method according to claim 1, wherein measuring the first parameter includes providing a flow sensor operatively coupled to such a patient's airway, wherein the flow sensor outputs a flow signal indicative of a flow of breathing to or from such a patient. 16. The method according to claim 1, wherein measuring the first parameter includes providing an oxygen analyzing element operatively coupled to such a patient's airway, wherein the oxygen analyzing element outputs an oxygen concentration signal indicative of an amount of oxygen in gas passing through the oxygen sensor. 17. The method according to claim 1, wherein measuring the second parameter includes providing a pulse oximeter sensor in contact with such a patient, wherein the pulse oximeter sensor outputs a signal indicative of an oxygen saturation SpO2 of such a patient. 18. The method according to claim 1, wherein inducing a change in such a patient's arterial oxygen concentration includes introducing a non-oxygen breathing gas into a stream of gas to be inhaled by such a patient or introducing oxygen into the stream of gas to be inhaled by such a patient. 19. The method according to claim 1, wherein inducing a change in such a patient's arterial oxygen concentration includes rebreathing gas exhaled by such a patient. 20. The method according to claim 19, wherein rebreathing includes removing carbon dioxide CO2 from the exhaled gas before the exhaled gas is rebreathed. 21. The method according to claim 1, wherein determining an estimate of the patient's cardiac output includes: determining a deviation of such a patient's oxygen uptake from a baseline oxygen uptake level occurring responsive to the induced change in such a patient's arterial oxygen concentration in step (2); determining a deviation of such a patient's arterial oxygen concentration from a baseline arterial oxygen concentration level occurring responsive to the induced change in such a patient's arterial oxygen concentration in step (2); and comparing the deviation in oxygen uptake to the deviation in arterial oxygen concentration. 22. The method according to claim 21, wherein determining the deviation of such a patient's oxygen uptake includes determining an effective area between the baseline oxygen uptake level and an oxygen uptake curve occurring responsive to the execution of step (2), and wherein determining the deviation of such a patient's arterial oxygen concentration includes determining an effective area between the baseline arterial oxygen concentration level and an arterial oxygen concentration curve occurring responsive to the execution of step (2). 23. The method according to claim 21, wherein determining the deviation of such a patient's oxygen uptake includes determining a slope of a line extending between the baseline oxygen uptake level and a point on an oxygen uptake curve occurring responsive to the execution of step (2), and wherein determining the deviation of such a patient's arterial oxygen concentration includes determining a slope of a line extending between the baseline arterial oxygen concentration level and a point on an arterial oxygen concentration curve occurring responsive to the execution of step (2). 24. The method according to claim 21, wherein determining the deviation of such a patient's oxygen uptake includes determining a magnitude between the baseline oxygen uptake level and a point on an oxygen uptake curve occurring responsive to the execution of step (2), and wherein determining the deviation of such a patient's arterial oxygen concentration includes determining a magnitude between the baseline arterial oxygen concentration level and a point on an arterial oxygen concentration curve occurring responsive to the execution of step (2). 25. The method according to claim 1, further comprising outputting, in human perceivable form, an indication of the cardiac output determined in step (4).
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (29)
Nobile John R. ; Triunfo ; Jr. John A. ; Sandor John L., Airway valve to facilitate re-breathing, method of operation, and ventilator circuit so equipped.
Walls James A. (71 Hampton Park E. Branford CT 06405) Howard Robert P. (E. Hartford CT), Method and apparatus for obtaining non-invasive cardio-pulmonary measurements.
Band David Marston,GBX ; Linton Nicholas William Fox,GBX ; Linton Robert Antony Fox,GBX ; O'Brien Terence Kevin,GBX, Method and apparatus for the measurement of cardiac output.
Orr Joseph A. ; Jaffe Michael B. ; Kuck Kai,DEX ; Haryadi Dinesh G.,INX, Method for compensating for non-metabolic changes in respiratory or blood gas profile parameters.
Orr Joseph A. ; Jaffe Michael B. ; Kuck Kai,DEX ; Haryadi Dinesh G.,INX, Method of continuously, non-invasively monitoring pulmonary capillary blood flow and cardiac output.
Haryadi Dinesh G.,INX ; Orr Joseph A. ; Kuck Kai,DEX ; Jaffe Michael B., Methods of measuring cardiac output using a non-invasively estimated intrapulmonary shunt fraction.
Haryadi Dinesh G.,INX ; Orr Joseph A. ; Kuck Kai,DEX ; Jaffe Michael B., Methods of non-invasively estimating intrapulmonary shunt fraction and measuring cardiac output.
Jerry M. Calkins ; Tadeusz M. Drzewiecki, Non-invasive cardiac output and pulmonary function monitoring using respired gas analysis techniques and physiological modeling.
Daniels Rich H. ; DelFavero John R. ; Feldman Barry J. ; Gunneson Paul B. ; Jaffe Michael B. ; Wigforss Eric P., Respiratory profile parameter determination method and apparatus.
Lynn, Lawrence A.; Lynn, Eric N., Centralized hospital monitoring system for automatically detecting upper airway instability and for preventing and aborting adverse drug reactions.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.