IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0768865
(2004-01-30)
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등록번호 |
US-7380550
(2008-06-03)
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발명자
/ 주소 |
- Sexton,Douglas A.
- Childers,Winthrop D.
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출원인 / 주소 |
- Hewlett Packard Development Company, L.P.
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인용정보 |
피인용 횟수 :
9 인용 특허 :
23 |
초록
▼
An inhalation system is disclosed that, in an exemplary embodiment, includes an ejector that ejects medicated droplets during an activation event, a conduit fluidically coupled to the ejector and configured to transport the droplets to a patient during an in-breath, and a particle detection system c
An inhalation system is disclosed that, in an exemplary embodiment, includes an ejector that ejects medicated droplets during an activation event, a conduit fluidically coupled to the ejector and configured to transport the droplets to a patient during an in-breath, and a particle detection system configured to determine whether the droplets have properly passed through the conduit and to the patient during an activation event. Also disclosed are methods for detecting particles in an inhaler system, with an exemplary method including generating a dose of medicament particles from an inhaler system; detecting particles emitted in the inhaler system; and determining if a desired particle flux has been achieved for inhalation by a patient.
대표청구항
▼
The invention claimed is: 1. An inhaler system, comprising: an inhaler housing; a conduit disposed within the inhaler housing configured to support particle flux therethrough; an inhaler control system disposed within the inhaler housing; a medicament supply system communicatively coupled to the in
The invention claimed is: 1. An inhaler system, comprising: an inhaler housing; a conduit disposed within the inhaler housing configured to support particle flux therethrough; an inhaler control system disposed within the inhaler housing; a medicament supply system communicatively coupled to the inhaler control system, wherein the medicament supply system includes a medicament ejector; and a detection system positioned to allow detection of particles in the conduit, wherein the detection system is adapted to differentiate between particles being inhaled by a patient and particles being exhaled by the patient. 2. The inhaler system of claim 1, further comprising at least one of the following components disposed within the housing: a display, an audio enunciator, and an activation switch. 3. The inhaler system of claim 1, further comprising at least one indicator communicatively coupled to the detection system, wherein the indicator is configured to alert a patient if the patient has not inhaled a desired dosage amount. 4. The inhaler system of claim 1, wherein the detection system includes: a laser disposed downstream from the medicament ejector, and a detector that detects the particles scattered by the laser. 5. The inhaler system of claim 1, wherein the detection system further includes a timer that is configured to communicate with the laser and detector to measure particle flux. 6. The inhaler system of claim 1, wherein the medicament ejector has an ejector face, the detection system configured to detect particles in a portion of the conduit, the portion is spaced sufficiently far from the ejector face to differentiate between droplets ejected from the medicament ejector and droplets properly passing through the conduit during the in-breath. 7. The inhaler system of claim 1, further comprising a warning device for warning the user if the proper particle flux has not been delivered through the conduit. 8. The inhaler system of claim 7, wherein the warning device is selected from the group consisting of: a light emitting device, an audible device, and a display device. 9. The inhaler system of claim 1, wherein the inhaler control system includes control electronics coupled to the medicament ejector and the detection system, the control electronics configured to respond in the event that the droplets have not passed through the conduit during an activation event. 10. An inhalation system comprising: an ejector that ejects medicated droplets during an activation event; a conduit fluidically coupled to the ejector and configured to transport the droplets to a patient during an in-breath; a particle detection system configured to determine whether the droplets have properly passed through the conduit and to the patient during an activation event; an information storage device storing calibration information indicative of a correlation estimation between medication absorbed by a patient versus a number of drops ejected from the ejector; and control electronics coupled to the ejector and the detection system, wherein the control electronics utilize the calibration information to select a number of drops to be ejected, and the control electronics updates the calibration information based on information received from the particle detection system. 11. An inhalation system comprising: an ejector that elects medicated droplets during an activation event; a conduit fluidically coupled to the ejector and configured to transport the droplets to a patient during an in-breath; a particle detection system configured to determine whether the droplets have properly passed through the conduit and to the patient during an activation event; and an inhaler control system communicatively coupled to the particle detection system and adapted to adjust at least one delivery parameter of the inhalation system, whereby the difference between desired dose and estimated delivered dose is reduced. 12. The inhalation system of claim 11, wherein the inhaler control system signals to the patient to increase the residence time of the particulate in the patient's lungs. 13. A method, comprising the steps of: generating a dose of medicament particles from an inhaler system; detecting particles emitted in the inhaler system; determining if a desired particle flux has been achieved for inhalation by a patient detecting particles exhaled into the inhaler system by the patient; and determining if a desired amount of dose of medicament has been delivered to a patient. 14. The method of claim 13, further comprising the step of ceasing the generation of medicament particles if a desired particle flux has not been achieved. 15. The method of claim 13, further comprising the step of indicating a fault to the patient if a desired particle flux has not been achieved. 16. The method of claim 15, further comprising the steps of: waiting for the particles to settle; and indicating to the patient that another dose of medicament particles may be taken. 17. The method of claim 13, further comprising the steps of: the inhaler system calibrating itself to compensate for any shortfall in the amount of dose delivered to the patient; and generating a subsequent dose of medicament particles from an inhaler system. 18. The method of claim 13, further comprising the step of ceasing the generation of medicament particles if a desired amount of dose has been achieved. 19. The method of claim 13, further comprising the step of indicating a fault to the patient if a desired amount of dose has not been achieved. 20. A method, comprising the steps of: generating a dose of medicament particles from an inhaler system; detecting particles emitted in the inhaler system; determining if a desired particle flux has been achieved for inhalation by a patient; and adjusting at least one delivery parameter of the inhaler, whereby the difference between desired dose and estimated delivered dose is reduced. 21. A method , comprising the steps of: generating a dose of medicament particles from an inhaler system; detecting particles emitted in the inhaler system; determining if a desired particle flux has been achieved for inhalation by a patient; and adjusting at least one delivery parameter of the inhaler, whereby variance between estimated delivered doses to the patient is reduced. 22. A method, comprising the steps of: generating a dose of medicament particles from an inhaler system; detecting particles emitted in the inhaler system; and determining if a desired particle flux has been achieved for inhalation by a patient; wherein the method is a feedback to an inhaler system controller that makes adjustments to delivery parameters based on the estimated delivered dose. 23. An inhaler system, comprising: means for generating a dose of medicament particles from an inhaler system; means for detecting particles emitted in the inhaler system; means for determining if a desired particle flux has been achieved for inhalation by a patient; means for indicating to patient that another dose of medicament particles may be taken; means for detecting particles exhaled into the inhaler system by the patient; and means for determining if a desired amount of dose of medicament has been delivered to a patient. 24. The inhaler system of claim 23, further comprising means for ceasing the generation of medicament particles if a desired particle flux has not been achieved. 25. The inhaler system of claim 23, further comprising means for indicating a fault to the patient if a desired particle flux has not been achieved. 26. The inhaler system of claim 23, further comprising means for ceasing the generation of medicament particles if a desired amount of dose has been achieved. 27. An inhaler system, comprising: means for generating a dose of medicament particles from an inhaler system; means for detecting particles emitted in the inhaler system; means for determining if a desired particle flux has been achieved for inhalation by a patient; means for indicating a fault to the patient if a desired amount of dose has not been achieved; means for calibrating the inhaler system to compensate for any shortfall in the amount of dose delivered to the patient; and means for generating a subsequent dose of medicament particles from an inhaler system.
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