A method of administering a drug whereby a fine drug powder can be accurately administered to a target site (in particular, a target site in the body cavity) via fluidization and spraying with a gas by using a micro tube. Concerning the administration mode, in particular, the drug alone or a biopoly
A method of administering a drug whereby a fine drug powder can be accurately administered to a target site (in particular, a target site in the body cavity) via fluidization and spraying with a gas by using a micro tube. Concerning the administration mode, in particular, the drug alone or a biopolymer is administered or the biopolymer is employed as a carrier in the above method. More specifically speaking, a method of administering a fine drug powder which comprises finely milling one or more types fine particles of the drug and/or the biopolymer, blending them each other, fluidizing the blend with a gas, then transporting the fluidized matter in a micro tube by the gas stream and spraying the fine drug powder from the tip of the micro tube toward the target site. Further, an administration method which comprises concentrically providing a capillary tube in the micro tube, supplying an aqueous solution of the drug and/or the biopolymer from the capillary tube into the gas stream and then mixing it with other fine particles of the drug and/or the biopolymer under transportation by the gas.
대표청구항▼
What is claimed is: 1. A method for administering a biopolymer having hemostatic or adhesion preventing functions, comprising the steps of: fluidizing fine particles of the biopolymer having hemostatic or adhesion preventing functions with a gas to prepare a homogenous mixed-phase fluid; transferri
What is claimed is: 1. A method for administering a biopolymer having hemostatic or adhesion preventing functions, comprising the steps of: fluidizing fine particles of the biopolymer having hemostatic or adhesion preventing functions with a gas to prepare a homogenous mixed-phase fluid; transferring the mixed-phase fluid through at least one micro-tube by flowing the gas; mixing a liquid with the mixed-phase fluid, the liquid being selected from the group consisting of a saline solution, an infusion solution, an aqueous solution of a drug and an aqueous solution of a biopolymer; the liquid being injected into the micro-tube thorough at least one inner tube so that the liquid is mixed with the mixed-phase fluid, wherein the inner tube is configured to be within the micro-tube; spraying the mixed liquid and the mixed-phase fluid toward a target site from an open tip of the micro-tube; wherein the mixed liquid and the mixed-phase fluid become a gel compound after the liquid and the mixed-phase fluid are mixed; whereby the fine particles of the biopolymer are capable of being sprayed as a gel compound toward the targct site to provide a seal upon the target site. 2. The method in accordance with claim 1, wherein the biopolymer is carboxymethyl cellulose. 3. The method in accordance with claim 1, wherein the biopolymer is carboxymethyl cellulose and the liquid is cationic cellulose aqueous solution. 4. The method in accordance with claim 1, wherein the step of fluidizing fine particles of a biopolymer with a gas is a step of fluidizing a finely powdered drug and fine particles of a biopolymer with a gas to prepare a homogenous mixed-phase fluid. 5. The method in accordance with claim 1, wherein the liquid comprises an aqueous solution of drug. 6. The method in accordance with claim 1, wherein the biopolymer comprises at least two types of biopolymers, the two types of biopolymers being a combination of an anionic biopolymer and a cationic biopolymer. 7. The method in accordance with claim 1, wherein the gas is carbon dioxide gas or nitrogen gas. 8. The method in accordance with claim 1, wherein the liquid comprises fibrinogen aqueous solution and thrombin aqueous solution. 9. A method for administering a biopolymer having hemostatic or adhesion preventing functions, comprising the steps of: fluidizing fine particles of the biopolymer having hemostatic or adhesive preventing functions with a gas to prepare a homogenous mixed-phase fluid, wherein the biopolymer comprises at least two types of biopolymers, the two types of biopolymers being a combination of an anionic biopolymer and a cationic biopolymer; transferring the mixed-phase fluid through at least onc micro-tube by flowing the gas; mixing a liquid with the mixed-phase fluid, the liquid being selected from the group consisting of a saline solution, an infusion solution, an aqueous solution of a drug and an aqueous solution of a biopolymer; the liquid being injected into the micro-tube thorough at least one inner tube so that the liquid is mixed with the mixed-phase fluid, wherein the inner tube is contained within the micro-tube; spraying the mixed liquid and the mixed-phase fluid toward a target sitc from an open tip of the micro-tube; wherein the mixed liquid and the mixed-phase fluid become a gel compound after the liquid and the mixed-phase fluid are mixed; whereby the fine particles of the biopolymer are capable of being sprayed as a gel compound toward the target site. 10. A method for administering a biopolymer having hemostatic or adhesion preventing functions, comprising the steps of: fluidizing fine particles of the biopolymer selected from the group consisting carboxymethyl celluloses, carboxyethyl celluloses, oxycelluloses, agaroses, chitins, chitosans, hyluronic acids, starches, glycogens, alginates, pectins, dextrans, chondroitin sulfates, gelatins and collagens with a gas to prepare a homogenous mixed-phase fluid; transferring the mixed-phase fluid through at least one micro-tube by flowing the gas; mixing a liquid with the mixed-phase fluid, the liquid being selected from the group consisting of a saline solution, an infusion solution, an aqueous solution of a drug and an aqueous solution of a biopolymer; thc liquid being injected into the micro-tube thorough at least one inner tube so that the liquid is mixed with the mixed-phase fluid, wherein the inner tube is configured to be within the micro-tube; spraying the mixed liquid and the mixed-phase fluid toward a target site from an open tip of the micro-tube; wherein the mixed liquid and the mixed-phase fluid become a gel compound after the liquid and the mixed-phase fluid are mixed; whereby the fine particles of the biopolymer are capable of being sprayed as a gel compound toward the target site to provide a seal upon the target site.
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이 특허에 인용된 특허 (11)
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Shelton, IV, Frederick E.; Setser, Michael E.; Doll, Kevin R.; Morgan, Jerome R., Articulating surgical stapling instrument incorporating a two-piece E-beam firing mechanism.
Woodard, Jr., James A.; Scheib, Charles J.; Boudreaux, Chad P.; Bruewer, Dean B.; Schwemberger, Richard F.; Schall, Christopher J.; Morgan, Jerome R.; Simms, Robert J.; Swayze, Jeffrey S.; Ouwerkerk, John N., Assembly for fastening tissue comprising a compressible layer.
Hess, Christopher J.; Weisenburgh, II, William B.; Morgan, Jerome R.; Voegele, James W.; Shelton, IV, Frederick E.; Uth, Joshua R., Cartridge assembly having a buttressing member.
Shelton, IV, Frederick E.; Morgan, Jerome R.; Yates, David C.; Baxter, III, Chester O.; Beckman, Andrew T., Charging system that enables emergency resolutions for charging a battery.
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Yates, David C.; Hall, Steven G.; Schellin, Emily A.; Shelton, IV, Frederick E., Conductor arrangements for electrically powered surgical instruments with rotatable end effectors.
Shelton, IV, Frederick E.; Harris, Jason L.; Beckman, Andrew T., Control techniques and sub-processor contained within modular shaft with select control processing from handle.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Detachable motor powered surgical instrument.
Shelton, IV, Frederick E.; Stokes, Michael J.; Parihar, Shailendra K.; Baxter, III, Chester O., Drive system decoupling arrangement for a surgical instrument.
Lytle, IV, Thomas W.; Leimbach, Richard L.; Kerr, Wendy A.; Swensgard, Brett E.; Sackett, Kevin D.; Overmyer, Mark D., Drive system lockout arrangements for modular surgical instruments.
Schmid, Katherine J.; Morgan, Jerome R.; Korvick, Donna L.; Shelton, IV, Frederick E., End effector comprising a tissue thickness compensator and progressively released attachment members.
Leimbach, Richard L.; Shelton, IV, Frederick E.; Morgan, Jerome R.; Schellin, Emily A., End effector detection and firing rate modulation systems for surgical instruments.
Shelton, IV, Frederick E.; Schmid, Katherine J.; Scheib, Charles J.; Aronhalt, Taylor W.; Swayze, Jeffrey S.; Contiliano, Joseph H.; Yang, Chunlin; Henderson, Cortney E.; Aldridge, Jeffrey L., End effector including an implantable arrangement.
Aldridge, Jeffrey L.; Yang, Chunlin; Scheib, Charles J.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Stammen, John L.; Ransick, Mark H.; Mutchler, Stephanie A.; Knight, Gary W., Expandable tissue thickness compensator.
Swayze, Jeffrey S.; Hueil, Joseph C.; Morgan, Jerome R.; Shelton, IV, Frederick E., Fastener cartridge assembly comprising a fixed anvil and a staple driver arrangement.
Swayze, Jeffrey S.; Hueil, Joseph C.; Morgan, Jerome R.; Shelton, IV, Frederick E., Fastener cartridge assembly comprising a fixed anvil and different staple heights.
Aronhalt, Taylor W.; Vendely, Michael J.; Widenhouse, Christopher W.; Shelton, IV, Frederick E., Fastener cartridge comprising a cutting member for releasing a tissue thickness compensator.
Aronhalt, Taylor W.; Vendely, Michael J.; Weaner, Lauren S.; Lloyd, Brandon J.; Shelton, IV, Frederick E.; Miller, Michael J.; Isaacs, Michael T.; Schellin, Emily A.; Hunt, John V.; Feds, John E., Fastener cartridge comprising a releasable tissue thickness compensator.
Aronhalt, Taylor W.; Vendely, Michael J.; Lloyd, Brandon J.; Miller, Michael J.; Setser, Michael E.; Shelton, IV, Frederick E., Fastener cartridge comprising a releasably attached tissue thickness compensator.
Weaner, Lauren S.; Aronhalt, Taylor W.; Vendely, Michael J.; Schellin, Emily A.; Shelton, IV, Frederick E., Fastener cartridge comprising a tissue thickness compensator and a gap setting element.
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Harris, Jason L.; Casella, Lucia M.; Zeiner, Mark S.; Smith, Bret W.; Crainich, Lawrence; Shelton, IV, Frederick E.; Morgan, Jerome R.; Worthington, Sarah A., Fastener cartridge for creating a flexible staple line.
Aronhalt, Taylor W.; Shelton, IV, Frederick E.; Vendely, Michael J.; Schellin, Emily A.; Zeiner, Mark S., Fastening system comprising a firing member lockout.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Feedback algorithms for manual bailout systems for surgical instruments.
Morgan, Jerome R.; Swayze, Jeffrey S.; Shelton, IV, Frederick E.; Schellin, Emily A.; Hall, Steven G., Firing member retraction devices for powered surgical instruments.
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Schellin, Emily A.; Vendely, Michael J.; Weaner, Lauren S.; Widenhouse, Christopher W.; Aronhalt, Taylor W.; Reynolds, II, Donald L.; Miller, Michael J.; Shelton, IV, Frederick E.; Barton, Trevor J., Implantable layers and methods for altering one or more properties of implantable layers for use with fastening instruments.
Vendely, Michael J.; Timmer, Mark D.; Donners, Jackie J.; Reynolds, II, Donald L.; Aronhalt, Taylor W.; Barton, Trevor J., Implantable layers and methods for modifying the shape of the implantable layers for use with a surgical fastening instrument.
Leimbach, Richard L.; Lytle, IV, Thomas W.; Kerr, Wendy A.; Swensgard, Brett E.; Sackett, Kevin D.; Overmyer, Mark D., Interchangeable shaft assemblies for use with a surgical instrument.
Overmyer, Mark D.; Swensgard, Brett E.; Adams, Shane R.; Lytle, IV, Thomas W.; Leimbach, Richard L.; Shelton, IV, Frederick E.; Houser, Kevin L., Interface systems for use with surgical instruments.
Hess, Christopher J.; Weisenburgh, II, William B.; Shurtleff, Carl J.; Shelton, IV, Frederick E., Lateral securement members for surgical staple cartridges.
Morgan, Jerome R.; Baxter, III, Chester O.; Shelton, IV, Frederick E.; Knight, Gary W., Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors.
Shelton, IV, Frederick E.; Overmyer, Mark D.; Yates, David C.; Harris, Jason L., Mechanisms for compensating for drivetrain failure in powered surgical instruments.
Hess, Christopher J.; Morgan, Jerome R.; Weisenburgh, II, William B.; Voegele, James W.; Ortiz, Mark S.; Stokes, Michael J.; Shurtleff, Carl J.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Bedi, James J.; Dunki-Jacobs, Adam R., Method for forming a staple.
Parihar, Shailendra K.; Koch, Jr., Robert L.; Shelton, IV, Frederick E., Modular motor driven surgical instruments with alignment features for aligning rotary drive shafts with surgical end effector shafts.
Kimsey, John S.; Nalagatla, Anil K.; Shelton, IV, Frederick E.; Houser, Kevin L., Modular motor driven surgical instruments with status indication arrangements.
Beckman, Andrew T.; Shelton, IV, Frederick E.; Morgan, Jerome R.; Yates, David C.; Baxter, III, Chester O.; Uth, Joshua R.; Savage, Jeffrey L.; Harris, Jason L., Modular stapling assembly.
Shelton, IV, Frederick E.; Morgan, Jerome R.; Harris, Jason L., Monitoring speed control and precision incrementing of motor for powered surgical instruments.
Laurent, Ryan J.; Swensgard, Brett E.; Smith, Bret W.; Schwemberger, Richard F.; Abbott, Daniel J.; Yates, David C.; Smith, Craig S.; Shelton, IV, Frederick E., Motor driven surgical fastener device with cutting member reversing mechanism.
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Swayze, Jeffrey S.; Uth, Joshua R.; Leimbach, Richard L.; Stammen, John L.; Tidwell, Samuel P.; Shelton, IV, Frederick E., Movable member for use with a tissue thickness compensator.
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Baber, Daniel L.; Swayze, Jeffrey S.; Beckman, Andrew T.; Miller, Christopher C.; Scheib, Charles J.; Shelton, IV, Frederick E.; Stokes, Michael J.; Stulen, Foster B., Multiple sensors with one sensor affecting a second sensor's output or interpretation.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Shelton, IV, Frederick E.; Houser, Kevin L., Power management through segmented circuit.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Shelton, IV, Frederick E.; Houser, Kevin L., Power management through segmented circuit and variable voltage protection.
Leimbach, Richard L.; Adams, Shane R.; Swensgard, Brett E.; Overmyer, Mark D., Power management through sleep options of segmented circuit and wake up control.
Smith, Bret W.; Abbott, Daniel J.; Schwemberger, Richard F.; Shelton, IV, Frederick E.; Boudreaux, Chad P.; Swensgard, Brett E.; Laurent, Ryan J., Powered surgical cutting and stapling apparatus with manually retractable firing system.
Smith, Bret W.; Abbott, Daniel J.; Schwemberger, Richard F.; Shelton, IV, Frederick E.; Boudreaux, Chad P.; Swensgard, Brett E.; Laurent, Ryan J., Powered surgical cutting and stapling apparatus with manually retractable firing system.
Aronhalt, Taylor W.; Vendely, Michael J.; Shelton, IV, Frederick E.; Schellin, Emily A.; Reynolds, II, Donald L., Releasable tissue thickness compensator and fastener cartridge having the same.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Morgan, Jerome R.; Scheib, Charles J.; Cropper, Michael S.; Aronhalt, Taylor W.; Hall, Steven G.; Timm, Richard W.; Lang, Matthew M., Retainer assembly including a tissue thickness compensator.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Morgan, Jerome R.; Scheib, Charles J.; Cropper, Michael S.; Aronhalt, Taylor W.; Hall, Steven G.; Timm, Richard W.; Lang, Matthew M., Retainer assembly including a tissue thickness compensator.
Spivey, James T.; Ortiz, Mark S.; Shelton, IV, Frederick E.; Morgan, Jerome R., Robotically-controlled surgical instrument with selectively articulatable end effector.
Leimbach, Richard L.; Overmyer, Mark D.; Swensgard, Brett E.; Adams, Shane R., Sensor arrangements for absolute positioning system for surgical instruments.
Shelton, IV, Frederick E.; Baxter, III, Chester O.; Swayze, Jeffrey S.; Harris, Jason L., Staple cartridge assembly including features for controlling the rotation of staples when being ejected therefrom.
Swayze, Jeffrey S.; Shelton, IV, Frederick E.; Vendely, Michael J.; Baxter, III, Chester O.; Harris, Jason L.; Aronhalt, Taylor W., Staple cartridge assembly without a bottom cover.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Aronhalt, Taylor W.; Schmid, Katherine J., Staple cartridge comprising a compressible layer.
Shelton, IV, Frederick E.; Murray, Michael A.; Hess, Christopher J.; Weisenburgh, II, William B.; Morgan, Jerome R.; Hall, Steven G., Staple cartridge comprising a staple driver arrangement.
Shelton, IV, Frederick E.; Weaner, Lauren S.; Morgan, Jerome R.; Vendely, Michael J.; Aronhalt, Taylor W.; Baxter, III, Chester O.; Zeiner, Mark S., Staple cartridge comprising a tissue thickness compensator.
Shelton, IV, Frederick E.; Baxter, III, Chester O.; Swayze, Jeffrey S.; Morgan, Jerome R.; Rhee, Sora; Aronhalt, Taylor W., Staple cartridge comprising a variable thickness compressible portion.
Shelton, IV, Frederick E.; Weaner, Lauren S.; Morgan, Jerome R.; Vendely, Michael J.; Aronhalt, Taylor W., Staple cartridge comprising an adjunct material.
Shelton, IV, Frederick E.; Baxter, III, Chester O.; Morgan, Jerome R.; Aronhalt, Taylor W.; Sidow, Brian R., Staple cartridge comprising an adjustable distal portion.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Aronhalt, Taylor W.; Schmid, Katherine J., Staple cartridge comprising an implantable layer.
Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Morgan, Jerome R.; Young, Joseph E., Staple cartridge comprising multiple regions.
Hess, Christopher J.; Morgan, Jerome R.; Shelton, IV, Frederick E.; Weisenburgh, II, William B., Staple cartridge comprising staples including a lateral base.
Schmid, Katherine J.; Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E., Staple cartridge including collapsible deck.
Schmid, Katherine J.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E.; Shelton, IV, Frederick E., Staple cartridge including collapsible deck arrangement.
Schmid, Katherine J.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E.; Shelton, IV, Frederick E., Staple cartridge including collapsible deck arrangement.
Swayze, Jeffrey S.; Hueil, Joseph C.; Morgan, Jerome R.; Shelton, IV, Frederick E., Stapling assembly configured to produce different formed staple heights.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Sterilization verification circuit.
Beckman, Andrew T.; Nalagatla, Anil K.; Hibner, John A.; Shelton, IV, Frederick E., Surgical apparatus configured to assess whether a performance parameter of the surgical apparatus is within an acceptable performance band.
Beckman, Andrew T.; Nalagatla, Anil K.; Koch, Jr., Robert L.; Hibner, John A.; Shelton, IV, Frederick E., Surgical apparatus configured to track an end-of-life parameter.
Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status.
Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status.
Huitema, Thomas W.; Scheib, Charles J.; Henderson, Cortney E.; Shelton, IV, Frederick E.; Harris, Jason L., Surgical end effectors with firing element monitoring arrangements.
Huitema, Thomas W.; Schellin, Emily A.; Hueil, Geoffrey C.; Shelton, IV, Frederick E., Surgical fastener cartridges with driver stabilizing arrangements.
Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical fastening apparatus with a rotary end effector drive shaft for selective engagement with a motorized drive system.
Shelton, IV, Frederick E.; Morgan, Jerome R.; Harris, Jason L.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical instrument assembly comprising a flexible articulation system.
Baxter, III, Chester O.; Dunki-Jacobs, Adam R.; Swayze, Jeffrey S.; Baber, Daniel L.; Shelton, IV, Frederick E., Surgical instrument assembly comprising a lockable articulation system.
Parihar, Shailendra K.; Kimsey, John S.; Koch, Jr., Robert L.; Nalagatla, Anil K.; Nguyen, Anthony T., Surgical instrument comprising a gap setting system.
Overmyer, Mark D.; Auld, Michael D.; Adams, Shane R.; Shelton, IV, Frederick E.; Harris, Jason L., Surgical instrument comprising a lockable battery housing.
Lytle, IV, Thomas W.; Overmyer, Mark D.; Adams, Shane R.; Leimbach, Richard L.; Shelton, IV, Frederick E.; Swensgard, Brett E.; Houser, Kevin L., Surgical instrument comprising interactive systems.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Surgical instrument control circuit having a safety processor.
Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument system comprising a firing system including a rotatable shaft and first and second actuation ramps.
Kerr, Wendy A.; Lytle, IV, Thomas W.; Overmyer, Mark D.; Swensgard, Brett E.; Sackett, Kevin D.; Leimbach, Richard L.; Houser, Kevin L.; Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument system comprising lockable systems.
Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument system configured to detect resistive forces experienced by a tissue cutting implement.
Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member.
Shelton, IV, Frederick E.; Baxter, III, Chester O., Surgical instrument with an anvil that is selectively movable about a discrete non-movable axis relative to a staple cartridge.
Hunter, Morgan R.; Schultz, Darwin L.; Worthington, Sarah A.; Shelton, IV, Frederick E.; Weaner, Lauren S.; Vendely, Michael J., Surgical instrument with articulating and axially translatable end effector.
Shelton, IV, Frederick E.; Baxter, III, Chester O.; Harris, Jason L.; Swayze, Jeffrey S., Surgical instruments with articulatable end effectors and improved firing beam support arrangements.
Shelton, IV, Frederick E.; Morgan, Jerome R.; Harris, Jason L.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical instruments with articulatable end effectors and movable firing beam support arrangements.
Hunter, Morgan R.; Schultz, Darwin L.; Dunki-Jacobs, Adam R.; Baxter, III, Chester O.; Swayze, Jeffrey S., Surgical instruments with tensioning arrangements for cable driven articulation systems.
Harris, Jason L.; Shelton, IV, Frederick E.; Baxter, III, Chester O., Surgical staple cartridges with driver arrangements for establishing herringbone staple patterns.
Overmyer, Mark D.; Yates, David C.; Shelton, IV, Frederick E.; Adams, Shane R.; Leimbach, Richard L., Surgical stapler having motor control based on an electrical parameter related to a motor current.
Overmyer, Mark D.; Yates, David C.; Shelton, IV, Frederick E.; Adams, Shane R.; Harris, Jason L., Surgical stapler having temperature-based motor control.
Schmid, Katherine J.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E.; Shelton, IV, Frederick E., Surgical stapler with stationary staple drivers.
Schmid, Katherine J.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E.; Shelton, IV, Frederick E., Surgical stapler with stationary staple drivers.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus including firing force regulation.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus including firing force regulation.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E., Surgical stapling apparatus with interlockable firing system.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E., Surgical stapling apparatuses with lockable end effector positioning systems.
Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling assembly comprising a selector arrangement.
Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Surgical stapling instrument configured to apply a compressive pressure to tissue.
Hess, Christopher J.; Weisenburgh, II, William B.; Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling instrument having a releasable buttress material.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Surgical stapling instrument system.
Huang, Zhifan F.; Boudreaux, Chad P.; Hueil, Joseph C.; Bruewer, Dean B.; Smith, David B., Surgical stapling instrument with an articulatable end effector.
Huang, Zhifan F.; Boudreaux, Chad P.; Hueil, Joseph C.; Bruewer, Dean B.; Smith, David B., Surgical stapling instrument with an articulatable end effector.
Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Surgical stapling instrument with lockout features to prevent advancement of a firing assembly unless an unfired surgical staple cartridge is operably mounted in an end effector portion of the instrument.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Systems and methods for controlling a segmented circuit.
Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Systems and methods for controlling a segmented circuit.
Shelton, IV, Frederick E.; Swensgard, Brett E.; Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Houser, Kevin L., Systems and methods for controlling a segmented circuit.
Shelton, IV, Frederick E.; Harris, Jason L.; Swensgard, Brett E.; Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D., Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures.
Shelton, IV, Frederick E.; Harris, Jason L.; Swensgard, Brett E.; Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D., Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures.
Anim, Jacqueline A.; Onukuri, Samardh; Silvestri, Jr., Anthony; Shelton, IV, Frederick E.; Clem, Michael F.; Vetro-Widenhouse, Tamara S., Tissue stapler having a thickness compensator comprising incorporating a hemostatic agent.
Shelton, IV, Frederick E.; Vetro-Widenhouse, Tamara S.; Yoo, Andrew C., Tissue stapler having a thickness compensator incorporating an anti-inflammatory agent.
Ming, Xintian; Huitema, Thomas W.; Rothenburger, Stephen J.; Shelton, IV, Frederick E., Tissue stapler having a thickness compensator incorporating an anti-microbial agent.
Henderson, Cortney E.; Aronhalt, Taylor W.; Yang, Chunlin; Scheib, Charles J.; Mandakolathur Vasudevan, Venkataramanan; Yoo, Andrew C.; Shelton, IV, Frederick E., Tissue stapler having a thickness compensator incorporating an oxygen generating agent.
Timm, Richard W.; Timmer, Mark D.; Widenhouse, Tamara; Lang, Matthew M.; Stammen, John L.; Knight, Gary W.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Mutchler, Stephanie A.; Ransick, Mark H.; Schmid, Katherine J.; Shelton, IV, Frederick E.; Baxter, III, Chester O., Tissue thickness compensator and method for making the same.
Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Yang, Chunlin; Henderson, Cortney E.; Aronhalt, Taylor W.; Scheib, Charles J.; Aldridge, Jeffrey L.; Schmid, Katherine J., Tissue thickness compensator comprised of a plurality of materials.
Mandakolathur Vasudevan, Venkataramanan; Aronhalt, Taylor W.; Aldridge, Jeffrey L.; Scheib, Charles J.; Yang, Chunlin; Schall, Christopher J.; Baxter, III, Chester O.; Chun, Iksoo; Bezwada, Rao S.; Conlon, Sean P.; Cropper, Michael S.; Uth, Joshua R.; Leimbach, Richard L.; Korvick, Donna L., Tissue thickness compensator comprising a plurality of capsules.
Gonzalez, Hamilton E.; Swayze, Jeffrey S.; Cropper, Michael S.; Scheib, Charles J.; Shelton, IV, Frederick E.; Johnson, Gregory W., Tissue thickness compensator comprising a plurality of layers.
Mandakolathur Vasudevan, Venkataramanan; Henderson, Cortney E.; Aronhalt, Taylor W.; Aldridge, Jeffrey L.; Scheib, Charles J.; Yang, Chunlin; Schall, Christopher J.; Baxter, III, Chester O.; Shelton, IV, Frederick E.; Contiliano, Joseph H.; Widenhouse, Tamara; Korvick, Donna L., Tissue thickness compensator comprising a reservoir.
Shelton, IV, Frederick E.; Schmid, Katherine J.; Scheib, Charles J.; Aronhalt, Taylor W.; Lang, Matthew M.; Hall, Steven G.; Baxter, III, Chester O., Tissue thickness compensator comprising at least one medicament.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Scheib, Charles J.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Stammen, John L.; Ransick, Mark H.; Mutchler, Stephanie A.; Knight, Gary W.; Cropper, Michael S.; Conlon, Sean P.; Swayze, Jeffrey S., Tissue thickness compensator comprising controlled release and expansion.
Timmer, Mark D.; Contiliano, Joseph H.; Aronhalt, Taylor W.; Yang, Chunlin; Scheib, Charles J.; Schmid, Katherine J.; Shelton, IV, Frederick E., Tissue thickness compensator comprising fibers to produce a resilient load.
Swayze, Jeffrey S.; Shelton, IV, Frederick E.; Widenhouse, Tamara; Widenhouse, Christopher W.; Aronhalt, Taylor W.; Scheib, Charles J., Tissue thickness compensator comprising structure to produce a resilient load.
Barton, Trevor J.; Vendely, Michael J.; Torain, Stephen M.; Hunt, John V.; Hueil, Geoffrey C.; Anim, Jacqueline A.; Attenweiler, Pamela M.; Shelton, IV, Frederick E.; Leimbach, Richard L.; Korvick, Donna L.; Uth, Joshua R.; Onukuri, Samardh, Tissue thickness compensator having improved visibility.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Aronhalt, Taylor W.; Johnson, Gregory W.; Stammen, John L.; Knight, Gary W.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Mutchler, Stephanie A.; Bedard, Timothy S., Tissue thickness compensators.
Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Aronhalt, Taylor W.; Johnson, Gregory W.; Stammen, John L.; Knight, Gary W.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Mutchler, Stephanie A.; Bedard, Timothy S., Tissue thickness compensators.
Alexander, III, Johnny H.; Henderson, Cortney E.; Miller, Christopher C.; Measamer, John P.; Schmid, Katherine J.; Shelton, IV, Frederick E.; Mutchler, Stephanie A.; Smith, Bret W.; Cropper, Michael S., Tissue thickness compensators for circular surgical staplers.
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