Aortic prosthetic devices
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
출원번호
US-0563384
(2004-07-06)
등록번호
US-7429269
(2008-09-30)
국제출원번호
PCT/IL04/000601
(2004-07-06)
§371/§102 date
20060420
(20060420)
국제공개번호
WO05/002466
(2005-01-13)
발명자
/ 주소
Schwammenthal,Ehud
Tuval,Yossi
Benary,Raphael
출원인 / 주소
대리인 / 주소
인용정보
피인용 횟수 :
295 인용 특허 :
45
초록
▼
A prosthetic device is provided for treatment of an aortic valve, having a compressed state for transarterial delivery and being expandable to an expanded state for implantation. The device includes an expandable support implantable in the expanded state of the prosthetic device in an aortic annulus
A prosthetic device is provided for treatment of an aortic valve, having a compressed state for transarterial delivery and being expandable to an expanded state for implantation. The device includes an expandable support implantable in the expanded state of the prosthetic device in an aortic annulus, and an inner envelope having an upstream portion that lines the inner surface of the support, and a downstream portion which, when the prosthetic device is in the expanded state, extends into an aorta and defines a diverging conical section having a diameter that gradually increases from an upstream end of the section to a downstream end of the section. The section is configured to produce, during systole, a non-turbulent blood flow into the aorta with pressure recovery at the downstream end of the section. Other embodiments are also described.
대표청구항
▼
What is claimed is: 1. A prosthetic device for use in the treatment of an aortic valve of a patient's heart, said prosthetic device having a compressed state for transarterial delivery and being expandable to an expanded state for implantation, said prosthetic device comprising: an expandable suppo
What is claimed is: 1. A prosthetic device for use in the treatment of an aortic valve of a patient's heart, said prosthetic device having a compressed state for transarterial delivery and being expandable to an expanded state for implantation, said prosthetic device comprising: an expandable support constructed so as to be implantable in the expanded state of the prosthetic device in an aortic annulus of the aortic valve; an inner envelope having an upstream portion that lines the inner surface of the support, and a downstream portion which, when the prosthetic device is in the expanded state, is configured to extend into an aorta and defines a diverging conical section having a diameter that gradually increases from an upstream end of the diverging conical section to a downstream end of the section, which diverging conical section is configured to produce, during systole, a non-turbulent blood flow into the aorta with pressure recovery at the downstream end of the diverging conical section; and a prosthetic valve coupled to the downstream portion of the envelope at the downstream end of the diverging conical section. 2. The prosthetic device according to claim 1, wherein, in the expanded state of the prosthetic device, said diverging conical section has an upstream end of 5-20 mm in diameter and a downstream end of 15-30 mm in diameter, and is of 15-45 mm in length. 3. The prosthetic device according to claim 2, wherein said upstream portion of the inner envelope includes a short straight section of uniform diameter within said aortic annulus effective to avoid flow separation through said upstream portion of the envelope. 4. The prosthetic device according to claim 3, wherein said short straight section has a length of 2-10 mm. 5. The prosthetic device according to claim 1, wherein said support includes two annular clamps engageable with the opposite sides of native leaflets of said aortic valve in the native leaflets' open positions for clamping the support to said leaflets. 6. The prosthetic device according to claim 5, wherein each of said two annular clamps includes an annular array of fingers. 7. The prosthetic device according to claim 6, wherein said support includes an annular array of bracing elements engageable with an inner surface of the aorta for bracing the prosthetic device within the aorta. 8. The prosthetic device according to claim 7, wherein said bracing elements are integrally formed at one end with said annular array of fingers of one of said annular clamps. 9. The prosthetic device according to claim 1, wherein said support, when the prosthetic device is in the expanded state extends to said downstream end of the diverging conical section, such that said inner envelope serves as a liner lining the inner surface of the support from said upstream end to said downstream end of the diverging conical section. 10. The prosthetic device according to claim 1, wherein said prosthetic valve comprises a plurality of leaflets movable to open and closed positions. 11. The prosthetic device according to claim 10, wherein said leaflets of the prosthetic valve are integral with said inner envelope. 12. The prosthetic device according to claim 1, wherein said diverging conical section of said inner envelope comprises a flexible pliable material. 13. The prosthetic device according to claim 1, wherein said diverging conical section of said inner envelope comprises a plurality of axially-extending reinforcing struts. 14. The prosthetic device according to claim 13, wherein said reinforcing struts are hingedly connected to said support. 15. The prosthetic device according to claim 1, wherein the support comprises a metal base.
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Seguin, Jacques; Börtlein, Georg, Prosthetic valve for transluminal delivery.
Seguin, Jacques; Börtlein, Georg, Prosthetic valve for transluminal delivery.
Seguin, Jacques; Börtlein, Georg, Prosthetic valve for transluminal delivery.
Sèguin, Jacques; Börtlein, Georg, Prosthetic valve for transluminal delivery.
Tuval, Yosi; Kovalsky, Igor, Prosthetic valve having tapered tip when compressed for delivery.
Kovalsky, Igor; Tuval, Yossi, Prosthetic valve support structure.
Hariton, Ilia; Harari, Boaz, Prosthetic valve with axially-sliding frames.
Vidlund, Robert; Schankereli, Kemal; Lozonschi, Lucian; Lutter, Georg, Prosthetic valves and related inventions.
Vidlund, Robert; Schankereli, Kemal; Lozonschi, Lucian; Lutter, Georg, Prosthetic valves and related inventions.
Rolando, Giovanni; Gaschino, Paolo; Achiluzzi, Monica F.; Carlino, Felice G., Prosthetic vascular conduit.
Rolando, Giovanni; Gaschino, Paolo; Achiluzzi, Monica; Carlino, Felice Giuseppe, Prosthetic vascular conduit and assembly method.
Rolando, Giovanni; Gaschino, Paolo; Achiluzzi, Monica; Carlino, Felice Giuseppe, Prosthetic vascular conduit and assembly method.
Rowe, Stanton J.; Wood, Larry L.; Bourang, Henry; Bakis, George; Spenser, Benjamin; Benichou, Netanel; Bash, Assaf; Keidar, Yaron, Rapid deployment prosthetic heart valve.
Pintor, Rafael; Scott, Michael J.; Chien, Thomas; Chen, Harvey H.; Yambao, August R.; Farhat, Lawrence J.; Phung, Andrew; Brunnett, William C.; Cristea, Carey L.; Walls, Sara M.; Zheng, Kevin W.; Kalam, Faisal; Zeng, Qinggang, Rapidly deployable surgical heart valves.
Pintor, Rafael; Scott, Michael J.; Zeng, Qinggang; Kim, Grace Myong; Chung, Visith; Campbell, Louis A.; Lin, David S.; Norasing, Peng; Ta, Edwin T., Rapidly deployable surgical heart valves.
Shalev, Alon, Reduced-strain extra-vascular ring for treating aortic aneurysm.
Quadri, Arshad; Ratz, J. Brent, Replacement heart valve and method.
Quadri, Arshad; Ratz, J. Brent; Michiels, Robrecht, Replacement heart valve and method.
Ratz, J. Brent; Pesce, Luca; Vad, Siddharth; Johnson, Garrett Dallas, Replacement heart valves and methods of delivery.
Quadri, Arshad; Ratz, J. Brent, Replacement heart valves, delivery devices and methods.
Quadri, Arshad; Ratz, J. Brent, Replacement heart valves, delivery devices and methods.
Quadri, Arshad; Ratz, J. Brent, Replacement heart valves, delivery devices and methods.
Ratz, J. Brent; Pesce, Luca; Rabito, Glen T.; Nguyen, Christine Thanh, Replacement mitral valve.
Rowe, Stanton J.; Wood, Larry L.; Bourang, Henry; Bakis, George; Spenser, Benjamin; Benichou, Netanel; Bash, Assaf; Keidar, Yaron, Replacement prosthetic heart valves.
Ryan, Timothy R.; Bonhoeffer, Philipp, Replacement prosthetic heart valves and methods of implantation.
Ryan, Timothy R.; Morrow, Joseph C., Replacement prosthetic heart valves and methods of implantation.
Quadri, Arshad; Ratz, J. Brent; Michiels, Robrecht, Replacement valve and method.
Brunnett, William C.; Stanislaus, Charles, Retaining mechanisms for prosthetic heart valves.
Meiri, Oded; Levi, Tamir S.; Witzman, Ofir, Retaining mechanisms for prosthetic valves.
Meiri, Oded; Levi, Tamir S.; Witzman, Ofir, Retaining mechanisms for prosthetic valves.
Meiri, Oded; Levi, Tamir; Witzman, Ofir, Retaining mechanisms for prosthetic valves.
Olson, Christopher; Rabito, Glen T.; Armer, Dustin P.; Ma, Minh; Marr, Devin; Huang, Mark; Okabe, Hiroshi; Stewart, Kevin; Curtis, Alison S.; Corso, Jr., Philip P., Retaining mechanisms for prosthetic valves.
Rowe, Stanton; Maisano, Francesco; Meiri, Oded, Retaining mechanisms for prosthetic valves and methods for using.
Hacohen, Gil, Rotation-based anchoring of an implant.
Lane, Randy Matthew; Nyuli, Colin A.; Marko, Alexei J.; Neale, Krista L., Sequentially deployed transcatheter mitral valve prosthesis.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Sinus-engaging valve fixation member.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Sinus-engaging valve fixation member.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Sinus-engaging valve fixation member.
Tuval, Yossi; Benary, Raphael; Kilemnik, Ido, Sinus-engaging valve fixation member.
Tuval, Yossi; Benary, Raphael; Kilemnik, Ido, Sinus-engaging valve fixation member.
Tuval, Yossi; Benary, Raphael; Kilemnik, Ido, Sinus-engaging valve fixation member.
DiPerna, Paul M., Slideable flow metering devices and related methods.
Brown, David, Solute concentration measurement device and related methods.
Pesce, Luca; Ratz, J. Brent, Stent.
Shalev, Alon, Stent fixation with reduced plastic deformation.
Tabor, Charles; Eberhardt, Carol E.; Laske, Timothy G.; Ryan, Timothy R.; Morrow, Joseph C.; Tam, Tammy Y.; Glynn, Brian A.; Rubin, Ann L. Brody; Tuchek, Michael J., Stent for prosthetic heart valves.
Tuval, Yosi; Sudin, Yuri; Kilemnik, Ido; Kovalsky, Igor; Benary, Raphael; Ezekiel, Guy, Stent loading tool and method for use thereof.
Shalev, Alon, Stent-graft with fixation elements that are radially confined for delivery.
Shalev, Alon, Stent-grafts with post-deployment variable radial displacement.
Lashinski, Randall T.; Bishop, Gordon B., Stentless aortic valve replacement with high radial strength.
Eberhardt, Carol E.; Tabor, Charles; Majkrzak, Carolyn; Ryan, Timothy R.; Denton, Melissa; Botrous, Maria; Shay, Janice L., Stents for prosthetic heart valves.
Eberhardt, Carol E.; Tabor, Charles; Majkrzak, Carolyn; Ryan, Timothy R.; Young, Melissa; Awad, Maria; Shay, Janice L., Stents for prosthetic heart valves.
Tabor, Charles; Eberhardt, Carol E.; Laske, Timothy G.; Ryan, Timothy R.; Morrow, Joseph C.; Tam, Tammy Y.; Glynn, Brian A.; Brody Rubin, Anne L.; Tuchek, J. Michael, Stents for prosthetic heart valves.
Tabor, Charles; Eberhardt, Carol E.; Laske, Timothy G.; Ryan, Timothy R.; Morrow, Joseph C.; Tam, Tammy Y.; Glynn, Brian A.; Brody Rubin, Anne L.; Tuchek, J. Michael, Stents for prosthetic heart valves.
Tabor, Charles; Eberhardt, Carol E.; Laske, Timothy G.; Ryan, Timothy R.; Morrow, Joseph C.; Tam, Tammy Y.; Glynn, Brian A.; Rubin, Anne L. Brody; Tuchek, J. Michael, Stents for prosthetic heart valves.
Benary, Raphael; Shalev, Alon, Stents incorporating a plurality of strain-distribution locations.
Christianson, Mark; Perrin, Chad; Tegels, Zachary; Ekvall, Craig; Vidlund, Robert, Structural members for prosthetic mitral valves.
Rolando, Giovanni; Gaschino, Paolo; Marchisio, Andrea; Achiluzzi, Monica, Support device for valve prostheses and corresponding kit.
Rolando, Giovanni; Ercolani, Mauro; Gaschino, Paolo; Marchisio, Andrea, Sutureless anchoring device for cardiac valve prostheses.
Rolando, Giovanni; Ercolani, Mauro; Gaschino, Paolo; Marchisio, Andrea, Sutureless anchoring device for cardiac valve prostheses.
Rosinko, Michael J.; Kruse, Geoffrey A.; Harris, Paul, System and method for detecting occlusions in an infusion pump.
Rosinko, Mike; Kruse, Geoffrey; Harris, Paul, System and method for detecting occlusions in an infusion pump.
Nguyen, Than; Seguin, Jacques; Komatsu, Stan; Nguyen, Hung; Boertlein, Georg, System and method for transapical delivery of an annulus anchored self-expanding valve.
Jimenez, Jorge H.; Greene, James L., Systems and methods for anchoring and sealing a prosthetic heart valve.
Quadri, Arshad; Ratz, J. Brent; Rabito, Glen T.; Johnson, Garrett Dallas, Systems and methods for sealing openings in an anatomical wall.
Pintor, Rafael; Scott, Michael J.; Chien, Thomas; Chen, Harvey H.; Yambao, August R.; Farhat, Lawrence J.; Phung, Andrew; Brunnett, William C.; Cristea, Carey L.; Walls, Sara M.; Zheng, Kevin W.; Kalam, Faisal; Zeng, Qinggang, Systems for rapidly deploying surgical heart valves.
Metzmaker, Thomas; Saint, Sean; Michaud, Michael; Rosinko, Michael J.; Swanson, Vance, Systems including vial adapter for fluid transfer.
Gross, Yossi; Hacohen, Gil; Miller, Eran; Zipory, Yuval, Techniques for percutaneous mitral valve replacement and sealing.
Gross, Yossi; Hacohen, Gil; Miller, Eran; Zipory, Yuval; Reich, Tal, Techniques for percutaneous mitral valve replacement and sealing.
Gross, Yossi; Hacohen, Gil; Miller, Eran; Zipory, Yuval; Reich, Tal; Kutzik, Meir, Techniques for percutaneous mitral valve replacement and sealing.
Gross, Yossi; Hacohen, Gil; Miller, Eran; Zipory, Yuval; Reich, Tal; Kutzik, Meir; Neeman, Rotem, Techniques for percutaneous mitral valve replacement and sealing.
Hacohen, Gil; Gross, Yossi; Miller, Eran; Zipory, Yuval; Reich, Tal, Techniques for percutaneous mitral valve replacement and sealing.
Vidlund, Robert; Schankereli, Kemal, Tethers for prosthetic mitral valve.
Shalev, Alon, Thermal energy application for prevention and management of endoleaks in stent-grafts.
Christianson, Mark; Perrin, Chad; Tegels, Zachary; Ekvall, Craig; Vidlund, Robert; Mai, Son; Evans, Michael, Thrombus management and structural compliance features for prosthetic heart valves.
Holecek, Arin N.; Majkrzak, Carolyn; Eberhardt, Carol E.; Millwee, Billie J.; Nguyen, Thao M.; Shay, Janice L.; Chiu, Cynthia H.; Kupumbati, Tara S., Tissue attachment devices and methods for prosthetic heart valves.
Tuval, Yosi; Benary, Raphael, Transapical delivery system with ventruculo-arterial overlfow bypass.
Weber, Josef, Transcatheter atrio-ventricular valve prosthesis.
Weber, Josef, Transcatheter atrio-ventricular valve prosthesis.
Seguin, Jacques; Bortlein, Georg, Transcatheter heart valves.
Seguin, Jacques; Bortlein, Georg, Transcatheter heart valves.
Seguin, Jacques; Bortlein, Georg, Transcatheter heart valves.
Lane, Randy Matthew; Nyuli, Colin A., Transcatheter mitral valve prosthesis.
Rust, Matthew J., Transcatheter valve structure and methods for valve delivery.
Quill, Jason; Clague, Cynthia T.; Rothstein, Paul T., Transcatheter valve with torsion spring fixation and related systems and methods.
Quill, Jason; Clague, Cynthia T.; Rothstein, Paul T., Transcatheter valve with torsion spring fixation and related systems and methods.
Bishop, Gordon B.; Uong, Do; Lashinski, Randall T., Translumenally implantable heart valve with formed in place support.
Bishop, Gordon B.; Uong, Do; Lashinski, Randall T., Translumenally implantable heart valve with formed in place support.
Lashinski, Randall T.; Bishop, Gordon B., Translumenally implantable heart valve with formed in place support.
Lashinski, Randall T.; Bishop, Gordon B., Translumenally implantable heart valve with multiple chamber formed in place support.
Shalev, Alon, Triple-collar stent-graft.
Lutter, Georg; Lozonschi, Lucian, Truncated cone heart valve stent.
Lutter, Georg; Lozonschi, Lucian, Truncated cone heart valve stent.
Lutter, Georg; Lozonschi, Lucian, Truncated cone heart valve stent.
Lutter, Georg; Lozonschi, Lucian, Truncated cone heart valve stent.
DiPerna, Paul M., Two chamber pumps and related methods.
Pintor, Rafael; Chau, Mark; Oba, Travis; Yambao, August; Campbell, Louis A.; Huntley, Tammy; Zeng, Qinggang; Cristea, Carey; Kalam, Faisal, Unitary quick connect prosthetic heart valve and deployment system and methods.
Pintor, Rafael; Chau, Mark; Oba, Travis; Yambao, August R.; Campbell, Louis A.; Huntley, Tammy; Zeng, Qinggang; Cristea, Carey L.; Kalam, Faisal, Unitary quick-connect prosthetic heart valve deployment methods.
Pintor, Rafael; Chau, Mark; Oba, Travis Zenyo; Yambao, August R.; Campbell, Louis A.; Huntley, Tammy; Zeng, Qinggang; Cristea, Carey L.; Kalam, Faisal, Unitary quick-connect prosthetic heart valve deployment system.
Lashinski, Randall T.; Bishop, Gordon B., Unstented heart valve with formed in place support structure.
Gloss, Michael; Groen, Timothy; Majkrzak, Carolyn; Nadian, Behrooz; Rust, Matthew; Ryan, Timothy; Weston, Matthew; Anderson, Marc; Birmingham, Evelyn; Casley, Mark; McGowan Smyth, Deirdre, Valve delivery tool.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve fixation member having engagement arms.
Ratz, J. Brent; Pesce, Luca; Vad, Siddharth; Landon, David Robert; Cooper, Alexander H.; Rabito, Glen T., Valve frame for a delivery system.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prostheses.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prosthesis fixation techniques using sandwiching.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prosthesis fixation techniques using sandwiching.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prosthesis fixation techniques using sandwiching.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prosthesis fixation techniques using sandwiching.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prosthesis implantation techniques.
Lamphere, David G.; Nguyen, Tuan Anh; Herrmann, Howard C., Valve prosthesis systems and methods.
Tuval, Yosi; Kilemnik, Ido; Benary, Raphael, Valve prosthetic fixation techniques using sandwiching.
Tuval, Yosi; Kovalsky, Igor; Kilemnik, Ido; Ben-Hamou, Eliyahu, Valve suturing and implantation procedures.
Tuval, Yossi; Kovalsky, Igor; Kilemnik, Ido; Benhamou, Eli, Valve suturing and implantation procedures.
Shalev, Alon, Vascular bands and delivery systems therefor.
Quadri, Arshad; Ratz, J. Brent, Vascular implant.
Quadri, Arshad; Ratz, J. Brent, Vascular implant.
Quadri, Arshad; Ratz, J. Brent, Vascular implant.
Quadri, Arshad; Ratz, J. Brent, Vascular implant.
Quadri, Arshad; Ratz, J. Brent, Vascular implant and delivery method.
Quadri, Arshad; Ratz, J. Brent, Vascular implant and delivery system.
Quadri, Arshad; Ratz, J. Brent, Vascular implant and delivery system.
Quadri, Arshad; Ratz, J. Brent, Vascular implant and delivery system.
Quadri, Arshad; Ratz, J. Brent, Vascular implant and delivery system.
Shalev, Alon; Benary, Rafi, Vascular prostheses for treating aneurysms.
Quadri, Arshad, Vascular prosthesis connecting stent.
Shalev, Alon; Benary, Raphael, Vascular prosthesis for treating aneurysms.
Haverkost, Patrick A.; Hill, Jason P.; Shoemaker, Susan M., Venous valve, system, and method with sinus pocket.
Styrc, Mikolaj Witold, valve prosthesis.
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