초록 ▼

A natural preservative composition obtained from plant materials provides antimicrobial activity for use as an antifungal agent. The antifungal agent is effective in inhibiting the growth of Epidermophyton floccosum, Trichophyton mentagrophytes and Microsporum canis. The antimicrobial agent has a M

A natural preservative composition obtained from plant materials provides antimicrobial activity for use as an antifungal agent. The antifungal agent is effective in inhibiting the growth of Epidermophyton floccosum, Trichophyton mentagrophytes and Microsporum canis. The antimicrobial agent has a MIC as low as 0.03 μl/ml capable of inhibiting and/or killing these organisms. The antimicrobial agent includes selective mixtures of Origanum vulgare L., Thymus vulgaris L., Cinnamomum zeylanicum Nees, Rosmarinus officinalis L., Lavandula officinalis L., Mentha piperita L., Citrus Limon L., Hydrastis canadensis L. and Olea europaea L.

대표청구항 ▼

What is claimed is: 1. A process for inhibiting the growth of fungus, said process comprising the step of applying an effective amount of an antifungal agent to the fungus, said antifungal agent including a mixture of plant materials comprising about 20 wt % to about 40 wt % Origanum vulgare L., ab

What is claimed is: 1. A process for inhibiting the growth of fungus, said process comprising the step of applying an effective amount of an antifungal agent to the fungus, said antifungal agent including a mixture of plant materials comprising about 20 wt % to about 40 wt % Origanum vulgare L., about 20 wt % to about 40 wt % Thymus vulgaris L., about 10 wt % to about 30 wt % Rosmarinus officinalis L., and about 5 wt % to about 15 wt % Lavandula officinalis L. wherein each of said plant materials is included in an amount effective to provide an antifungal effect and where the percentages are based on the total weight of the antifungal agent. 2. The process of claim 1, wherein said antifungal agent further comprises about 5 wt % to 15 wt % Cinnamomum zeylanicum Nees. 3. The process of claim 1, wherein said antifungal agent further comprises Hydrastis canadensisL. 4. The process of claim 1, wherein said fungus is selected from the group consisting of pathogenic Epidermophyton, Trichophyton, and Microsporum. 5. The process of claim 1, wherein said antifungal agent comprises at least 30 wt % Origanum vulgare L., and at least 30 wt % Thymus vulgaris L. and at least 20 wt % Rosmarinus officinalis L., based on the total weight of the antifungal agent. 6. The process of claim 5, wherein said antifungal agent further comprises at least 10 wt % Cinnamomum zeylanicum Nees based on the total weight of the antifungal agent. 7. The process of claim 1, wherein said antifungal agent comprises at least 10 wt % Lavandula officinalis L. 8. The process of claim 7, wherein said antifungal agent further comprises about 0.001 wt % to about 0.005 wt % Olea europaea L. 9. The process of claim 1, wherein said antifungal agent is dispersed in an aqueous camer. 10. The process of claim 1, wherein said antifungal agent further comprises Olea europaea L., Mentha piperita L. and Citrus Limon L. 11. The process of claim 1, wherein said plant materials are plant extracts and are included in amounts effective to provide an antifungal effect. 12. The process of claim 1, wherein said plant materials are present in effective amounts to provide an antifungal amount of a compound selected from the group consisting of carvacrol, thymol, cinnamaldehyde, eugenol, cineole, camphor, α-pinene, rosmarinic acid, linalol, linalyl acetate, berberine and hydrastine, and mixtures thereof. 13. A process for treating dermatophytes on the skin or nail of an animal, said process comprising the steps of: topically contacting the dennatophytes on the skin or nail of an animal in need thereof with an antifungal composition including an effective amount of an antifungal agent, said antifungal agent comprising a mixture of about 20 wt % to 40 wt % Origanum vulgare L., about 20 wt % to 40 wt % Thymus vulgaris L., about 10 wt % to 30 wt % Rosmarinus officinalis L., Lavandula officinalis L., Hydrastis canadensis L, and Olea europaea, where the percentages are based on the total weight of the antifungal agent. 14. The process of claim 13, wherein said antifungal composition further comprises an aqueous camer. 15. The process of claim 13, wherein said antifungal agent further comprises Cinnamomum zeylanicum Nees. 16. The process of claim 13, wherein said antifungal agent comprises at least 30 wt % Origanum vulgare L., at least 30 wt % Thymus vulgaris L., and at least 20 wt % Rosmarinus officinalis L. 17. The process of claim 13, wherein said antifungal agent further comprises about 5 wt % to 15 wt % Cinnamomum zeylanicum Nees in an amount effective to provide an antifungal effect. 18. The process of claim 13, wherein said antifungal agent further comprises about 1 wt % to 5 wt % Mentha piperita L. and about 1 wt % to 5 wt % Citrus Limon L. 19. The process of claim 13, wherein said dermatophytes are selected from the group consisting of Epidermophyton, Trichophyton, and Microsporum. 20. An antidermatophytic composition, comprising: an antidermatophytic agent comprising a mixture of plant material extracts of about 20 wt % to 40 wt % Origanum vulgare L., about 20 wt % to 40 wt % Thymus vulgaris L., about 10 wt % to 30 wt % Rosmarinus officinalis L., and about 5 wt % to 15 wt % Lavandula officinalis L. in amounts effective to provide an antidermatophytic effect when applied topically to an animal, and a carrier for said antidermatophytic agent, wherein said antidermatophytic agent is present in said carrier in an amount effective to provide an antifungal effect. 21. The composition of claim 20, wherein said antidermatophytic agent is effective in inhibiting the growth of Epidermophyton, Trichophyton, and Microsporum. 22. The composition of claim 20, wherein said carrier is an aqueous carrier. 23. The composition of claim 20, wherein said plant materials are present in amounts to provide a dermatophytic inhibiting amount of a compound selected from the group consisting of carvacrol, thymol, cinnamaldehyde, eugenol, cineole, camphor, α-pinene, rosmarinic acid, linalol, linalyl acetate, berberine and hydrastine, and mixtures thereof. 24. The composition of claim 20, wherein said antidermatophytic agent further comprises about 0.001 wt % to about 0.005 wt % Olea europaea L. 25. The composition of claim 24, wherein said antidermatophytic agent comprises about 5 wt % to 15 wt % Cinnamomum zeylanicum Nees. 26. The composition of claim 20, wherein said antidermatophytic agent consists essentially of Origanum vulgare L., Thymus vulgaris L., Cinnamomum zeylanicum Nees, Rosmarinus officinalis L., Lavandula officinalis L., Hydrastis canadensis L. 27. The composition of claim 20, wherein said antidermatophytic agent consists essentially of Origanum vulgare L., Thymus vulgaris L., Cinnamomum zeylanicum Nees, Rosmarinus officinalis L., Lavandula officinalis L., Hydrastis canadensis L., Olea europaea L., Mentha piperita L. and Citrus Limon L.