Flexible mixing bag for mixing solids, liquids, and gases
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B01F-015/00
B01F-013/06
B01F-013/00
B01F-015/02
B01F-015/06
B01F-007/18
B65D-030/10
출원번호
US-0831735
(2007-07-31)
등록번호
US-7431494
(2008-10-07)
발명자
/ 주소
Zambaux,Jean Pascal
출원인 / 주소
Advanced Technology Materials, Inc.
대리인 / 주소
Gustafson,Vincent K.
인용정보
피인용 횟수 :
14인용 특허 :
19
초록▼
In an embodiment, an apparatus includes a disposable and flexible mixing tank, configurable as a bag, having a sealed sleeve therein for arrangement of a mixing device. The volume of the mixing tank is defined by an inner wall of the mixing tank and an inner wall of the sleeve. The mixing tank may b
In an embodiment, an apparatus includes a disposable and flexible mixing tank, configurable as a bag, having a sealed sleeve therein for arrangement of a mixing device. The volume of the mixing tank is defined by an inner wall of the mixing tank and an inner wall of the sleeve. The mixing tank may be used to mix, store, reconstitute and/or dispense materials therein. Draining of a mixture may be aided with pressurized gas. Heating or cooling of the contents of a mixing tank may be accomplished with a thermal exchange fluid disposed within a thermal exchange vessel and in thermal communication with the tank.
대표청구항▼
What is claimed is: 1. A mixing apparatus comprising: a hollow mixing container having at least one interior wall; a mixing paddle adapted to engage a support rod mechanically coupleable to receive kinetic energy from a kinetic energy source, the mixing paddle having at least one widened paddle por
What is claimed is: 1. A mixing apparatus comprising: a hollow mixing container having at least one interior wall; a mixing paddle adapted to engage a support rod mechanically coupleable to receive kinetic energy from a kinetic energy source, the mixing paddle having at least one widened paddle portion that is wider than a nominal diameter or cross-sectional width of the support rod; a coupling guide joined to the mixing container, the coupling guide defining an aperture sized to permit pivotal arrangement of the support rod between the kinetic energy source and the mixing container; an integral sleeve sealingly and permanently welded proximate the coupling guide aperture to any of the container and the coupling guide, the sleeve having a closed end protruding into the interior of the hollow container, having at least one exterior wall, and defining a cavity containing the mixing paddle, the cavity having at least one widened cavity portion disposed about the at least one widened paddle portion; a drain port associated with the mixing container; and at least one inlet port associated with the mixing container; wherein (i) the at least one interior wall of the mixing container and the at least one exterior wall of the sleeve encloses a volume, (ii) the sleeve serves as an isolation barrier between the volume and the mixing paddle, and (iii) the mixing container is adapted to permit pressure-assisted draining of any contents thereof. 2. The mixing apparatus of claim 1, wherein the mixing container comprises a mixing bag comprising a substantially transparent polymeric film material. 3. The mixing apparatus of claim 1, wherein said at least one inlet port is adapted for coupling to a source of pressurized gas. 4. The mixing apparatus of claim 3, coupled in fluid-receiving relationship to a source of pressurized gas. 5. The mixing container of claim 1, wherein the sleeve is sized and shaped to be substantially form-fitting around the mixing paddle. 6. The mixing container of claim 1, wherein any of the mixing container and the sleeve comprises a polymeric film. 7. The mixing container of claim 1, wherein each of the mixing bag and the sleeve comprises a polymeric film, and the polymeric film of the mixing bag has substantially the same composition as the polymeric film of the sleeve. 8. A mixing system including the mixing apparatus of claim 1 coupled to a kinetic energy source. 9. A mixing method employing a mixing apparatus including (i) a kinetic energy source, (ii) a hollow mixing bag having a flexible integral sleeve joined thereto with a closed end of the sleeve protruding into the mixing bag, and having an associated drain port and an associated at least one inlet port, and (iii) a mixing paddle enveloped by the sleeve and adapted to receive a support rod coupleable to the kinetic energy source, wherein at least one interior wall of the bag and an exterior wall of the sleeve defines an interior volume, and the sleeve serves as an isolation barrier between the interior volume and the mixing paddle, the method comprising the steps of: supplying at least two components of a mixture to the interior volume; engaging the support rod between the kinetic energy source and the mixing paddle; mixing the at least two components by moving the enveloped mixing paddle in a closed curvilinear path within the interior volume without continuous rotation of the support rod about a longitudinal axis defined by the support rod to combine the at least two components and form said mixture; supplying pressurized gas to the container via any inlet port of the at least one inlet port; and draining at least a portion of said mixture via said drain port. 10. The method of claim 9, wherein the moving step comprises moving the mixing element within the tank through a defined path at a nonzero angle relative to a substantially central vertical axis of the tank. 11. The method of claim 9, wherein the closed curvilinear path comprises a substantially circular path. 12. The method of claim 9, wherein the mixing bag comprises a coupling guide defining an aperture sized and shaped to permit pivotal arrangement of the support rod between the kinetic energy source and the mixing bag, and the mixing step includes pivotally moving support rod through the coupling guide to direct the mixing paddle in the closed curvilinear path. 13. The method of claim 9, wherein said supplying of at least two components to the interior volume is performed through any of the at least one inlet port. 14. A mixing apparatus comprising: a hollow mixing container having at least one interior wall; a mixing paddle adapted to engage a support rod mechanically coupleable to receive kinetic energy from a kinetic energy source, the mixing paddle having at least one widened paddle portion that is wider than a nominal diameter or cross-sectional width of the support rod; a coupling guide joined to the mixing container, the coupling guide defining an aperture sized to permit pivotal arrangement of the support rod between the kinetic energy source and the mixing container; an integral sleeve sealingly and permanently welded proximate the coupling guide aperture to any of the container and the coupling guide, the sleeve having a closed end protruding into the interior of the hollow container, having at least one exterior wall, and defining a cavity containing the mixing paddle, the cavity having at least one widened cavity portion disposed about the at least one widened paddle portion; a thermal exchange vessel arranged to contain a thermal exchange fluid in thermal communication with at least a portion of the mixing container; and a thermal exchange element disposed in at least intermittent thermal communication with the thermal exchange fluid; wherein the at least one interior wall of the mixing container and the at least one exterior wall of the sleeve encloses a volume, and the sleeve serves as an isolation barrier between the volume and the mixing paddle. 15. The mixing apparatus of claim 14, wherein the mixing container comprises a mixing bag comprising a substantially transparent polymeric film material. 16. The mixing apparatus of claim 14, wherein the thermal exchange vessel comprises a secondary containment vessel containing at least a substantial portion of said mixing container. 17. The mixing apparatus of claim 14, wherein the thermal exchange vessel substantially envelops the mixing container. 18. The mixing apparatus of claim 14, wherein the thermal exchange vessel is disposed exterior to the mixing container. 19. The mixing apparatus of claim 14, wherein said the thermal exchange vessel and said mixing container define a substantially sealed gap or space therebetween adapted to contain said thermal exchange fluid. 20. The mixing apparatus of claim 14, further comprising a circulation element adapted to circulate the thermal exchange fluid in or through the thermal exchange vessel. 21. The mixing apparatus of claim 14, further comprising a temperature control element, wherein said apparatus is adapted to alter any of temperature and circulation of said thermal exchange fluid responsive to a signal provided by said temperature control element. 22. The mixing apparatus of claim 14, further comprising a temperature control element controlling temperature of said mixture by affecting any of temperature and circulation of said thermal exchange fluid. 23. The mixing container of claim 14, wherein the sleeve is sized and shaped to be substantially form-fitting around the mixing paddle. 24. The mixing container of claim 14, wherein any of the mixing container and the sleeve comprises a polymeric film. 25. The mixing container of claim 14, wherein each of the mixing bag and the sleeve comprises a polymeric film, and the polymeric film of the mixing bag has substantially the same composition as the polymeric film of the sleeve. 26. A mixing system including the mixing apparatus of claim 14 coupled to a kinetic energy source. 27. A material processing method employing a mixing apparatus including (i) a kinetic energy source, (ii) a hollow mixing bag having a flexible integral sleeve joined thereto with a closed end of the sleeve protruding into the mixing bag, and (iii) a mixing paddle enveloped by the sleeve and adapted to receive a support rod coupleable to the kinetic energy source, wherein at least one interior wall of the bag and an exterior wall of the sleeve defines an interior volume, and the sleeve serves as an isolation barrier between the interior volume and the mixing paddle, and (iv) a thermal exchange vessel arranged to contain a thermal exchange fluid in thermal communication with at least a portion of the mixing container, the method comprising the steps of: supplying at least two components of a mixture to the interior volume; engaging the support rod between the kinetic energy source and the mixing paddle; mixing the at least two components by moving the enveloped mixing paddle in a closed curvilinear path within the interior volume without continuous rotation of the support rod about a longitudinal axis defined by the support rod to combine the at least two components and form said mixture; and controlling temperature of said mixture by altering any of temperature and circulation of said thermal exchange fluid. 28. The method of claim 27, wherein the moving step comprises moving the mixing element within the tank through a defined path at a nonzero angle relative to a substantially central vertical axis of the tank. 29. The method of claim 27, wherein the closed curvilinear path comprises a substantially circular path. 30. The method of claim 27, wherein the mixing bag comprises a coupling guide defining an aperture sized and shaped to permit pivotal arrangement of the support rod between the kinetic energy source and the mixing bag, and the mixing step includes pivotally moving support rod through the coupling guide to direct the mixing paddle in the closed curvilinear path. 31. The method of claim 27, wherein the thermal exchange vessel comprises a secondary containment vessel containing at least a substantial portion of said mixing container. 32. The method of claim 27, wherein the thermal exchange vessel substantially envelops the mixing container. 33. The method of claim 27, wherein the thermal exchange vessel is disposed exterior to the mixing container. 34. The method of claim 27, further comprising circulating said thermal exchange fluid in or through the thermal exchange vessel. 35. The method of claim 27, further comprising altering any of temperature and circulation of said thermal exchange fluid responsive to a signal provided by a temperature control element. 36. The method of claim 27, further comprising controlling temperature of said mixture by affecting any of temperature and circulation of said thermal exchange fluid.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (19)
Priebe,Ryan; O'Dougherty,Kevin T.; Cheesebrow,Nicholas, Apparatus and method for dispensing high-viscosity liquid.
Cadogan, David Phillip; Davidson, Scott Lester; Edwards, Thomas Joseph; Lin, John Kun Hung; Lloyd, Steven Michael; McKee, Tony Ray, Bioprocess container, bioprocess container mixing device and method of use thereof.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.