초록 ▼

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.

대표청구항 ▼

What is claimed is: 1. An extracardiac pumping system for supplementing blood circulation through a patient without any component thereof being connected to the patient's heart, the extracardiac system comprising: a pump configured to pump blood through the patient at subcardiac volumetric rates, s

What is claimed is: 1. An extracardiac pumping system for supplementing blood circulation through a patient without any component thereof being connected to the patient's heart, the extracardiac system comprising: a pump configured to pump blood through the patient at subcardiac volumetric rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; a first conduit having a first distal end sized and configured to fluidly couple to a non-primary blood vessel, the first conduit also being fluidly coupled to the pump to conduct blood between the pump and the non-primary blood vessel; and a second conduit having a first distal end sized and configured to be positioned at least in part within the non-primary blood vessel and within the first conduit, the second conduit being fluidly coupled to the pump to conduct blood between the pump and the patient, the first conduit configured to permit the second conduit to sealably extend through a wall of said first conduit to form an internal lumen within the conduit; whereby the first conduit may be fluidly coupled to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure through a single site. 2. The extracardiac pumping system of claim 1, wherein the first conduit is configured as an inflow conduit and the second conduit is configured as an outflow conduit. 3. The extracardiac pumping system of claim 1, wherein the first conduit is configured as an outflow conduit and the second conduit is configured as an inflow conduit. 4. The extracardiac pumping system of claim 1, wherein the first conduit comprises an insertion site in said first conduit wall sized to tightly fit over the exterior wall of the second conduit extending therethrough and configured to permit a reliable seal between the first conduit wall and the exterior of the second conduit. 5. The extracardiac pumping system of claim 4, further comprising a branched portion on the first conduit located between the first and second end of said first conduit, the insertion site being positioned on said branched portion. 6. The extracardiac pumping system of claim 1, wherein the first conduit comprises a connector extending from said first conduit configured to sealably connect to a distal end of said second conduit; the first conduit further comprising an internal lumen in sealed fluid communication with said connector to permit fluid communication between the second conduit and the internal lumen when the distal end of the second conduit is connected to the connector without said fluid residing in said second conduit significantly leaking into the first conduit. 7. The extracardiac pumping system of claim 1, wherein the pump is a rotary pump. 8. The extracardiac pumping system of claim 1, wherein the pump is implantable. 9. The extracardiac pumping system of claim 1, wherein the system is implantable. 10. The extracardiac pumping system of claim 1, wherein the first conduit is configured to couple to the blood vessel via an anastomosis procedure. 11. A method for treating a patient comprising: connecting a first end of a first conduit to a first blood vessel using a minimally invasive procedure to permit the flow of blood between a pump and the first blood vessel,; fluidly coupling a distal end of a second conduit, which is fluidly coupled to the pump at a proximal end, to the patient's vasculature through the first conduit and through at least a part of the first blood vessel ;and operating the pump to perfuse blood through the patient's circulatory system at volumetric rates that are on average subcardiac between the first blood vessel and the same or different blood vessel. 12. The method of claim 11, wherein the step of fluidly coupling a distal end of the second conduit to the patient's vasculature comprises directing the distal end of the second conduit through an insertion site positioned on said first conduit. 13. The method of claim 11, wherein the step of fluidly coupling a distal end of the second conduit to the patient's vasculature comprises connecting the distal end of the second conduit to a connector extending from said first conduit. 14. The extracardiac pumping system of claim 11, wherein the first conduit is configured to couple to the blood vessel via an anastomosis procedure.