초록 ▼

Polymeric compositions that include polyurethane polymers derived from a polyisocyanate compound and a polyactive hydrogen compound. The polyurethane compound is at least partially endcapped with a group including at least one antimicrobial quaternary ammonium compound. The polymeric composition of

Polymeric compositions that include polyurethane polymers derived from a polyisocyanate compound and a polyactive hydrogen compound. The polyurethane compound is at least partially endcapped with a group including at least one antimicrobial quaternary ammonium compound. The polymeric composition of the present invention is capable of forming a self-supporting film. The polymeric compositions are suitable for coating substrates to effectively kill or prevent the growth of microorganisms such as bacteria, mold, mildew, algae fungi and the like. The polymeric compositions are particularly useful for protecting construction materials used in moist, outdoor environments to prevent discoloration or decay from microorganisms and for surfaces in health care facilities to mitigate the spread of pathogens.

대표청구항 ▼

We claim: 1. A polymeric composition comprising a polyurethane polymer derived from a polyisocyanate compound and a polyactive hydrogen compound, said polyurethane having an effective amount of covalently bound, antimicrobially active ammonium groups pendant to the polyurethane polymer in a termina

We claim: 1. A polymeric composition comprising a polyurethane polymer derived from a polyisocyanate compound and a polyactive hydrogen compound, said polyurethane having an effective amount of covalently bound, antimicrobially active ammonium groups pendant to the polyurethane polymer in a terminal position and/or as a side chain along the polyurethane polymer backbone, wherein the antimicrobially active ammonium group is derived from a compound of the formula (I): description="In-line Formulae" end="lead"[CH3(CH2)x(C(O)NH(CH2) y)p]qN⊕(R4)m--(CH2)zLHQ⊖ (I)description="In-line Formulae" end="tail" wherein: m is 1 or 2; p is 1; and q=1 or 2 provided that m+q=3; x is 6 to 20; y is 2-8; z is 2-10; L is O, S, NR5 or NH; where R5 is C1-4 alkyl or benzyl; each R4 is independently C1-4 alkyl, phenyl or C6-8 aralkyl; and Q⊖ is halogen, alkyl sulfate, or carboxylate, sulfonate, sulfate, phosphonate or phosphate; or an alkylaminoacrylate compound of the formula (II): wherein: R1 is H or CH3; R5 is a C2-8 alkylene; Q⊖ is a halogen, alkyl sulfate, alkylsulfonate or carboxylate; Z⊕is-N⊕(R4)2R3,-N ⊕R4(R3)2, wherein: R3 is C8-20 alkyl, benzyl, or substituted benzyl; each R4 is independently C1-4 alkyl, phenyl or C6-8 aralkyl; and R6 is H or C1-4 alkyl. 2. The polymeric composition of claim 1, wherein the antimicrobial quaternary ammonium group is derived from a compound of formula (I) and is an alkylamidopropyldimethylhydroxyalkyl ammonium salt. 3. The polymeric composition of claim 1, wherein the polyurethane polymer comprises a cationic stabilizing moiety. 4. The polymeric composition of claim 1, wherein the at least one antimicrobial quaternary ammonium group is derived from an alkylaminoacrylate compound of the formula (II) and is located on an addition polymerized group and wherein said polyurethane polymer is derived from a monol vinylic compound and wherein the total equivalents of isocyanate used to form said polyurethane polymer is greater than the equivalents of active hydrogen groups contributed by said polyactive hydrogen compound used to form said polyurethane polymer and said monol or polyol vinylic compound, and the addition polymerization group is formed by reaction of said monol or polyol vinylic compound with a vinylic compound having at least one antimicrobial quaternary ammonium group and wherein said monol vinylic compound is selected from allyl alcohol, allyl amine, or a hydroxyalkyl acrylic compound of the formula: wherein: Y is O or NH; R1 is H or CH3; R2 is a C2-8 alkylene; or mixtures thereof. 5. The polymeric composition of claim 4, wherein the monol vinylic compound is hydroxyethylmethacrylate or hydroxyethylacrylate. 6. The polymeric composition of claim 1, wherein the alkylaminoacrylate compound of the formula (II) is selected from the group of N,N-dimethyl-N-alkyl-N-alkylmethacroyl ammonium salts such as N,N-dimethyl-N-dodecyl-N-ethylmethacroyl salt, N,N-dimethyl-N-hexadecyl-N-ethylmethacroyl salt, N,N-dimethyl-N-benzyl-N-lauroylmethacoryl salt, N,N-dimethyl-N-(2,4-dichlorobenzyl)-N-ethylmethacroyl salt, N,N-diethyl-N-hexadecyl-N-ethylmethacroyl salt, wherein the counter ion is selected from chloride, bromide, iodide, C1-4 alkyl sulfate, sulfate, or carboxylate. 7. An article comprising a substrate coated with the polymeric composition according to claim 1. 8. A polymeric composition comprising a polyurethane polymer derived from a polyisocyanate compound and a polyactive hydrogen compound, said polyurethane having an effective amount of covalently bound, antimicrobially active ammonium groups pendant to the polyurethane polymer in a terminal position and/or as a side chain along the polyurethane polymer backbone, wherein the antimicrobially active ammonium group is derived from a compound of the formula (III): description="In-line Formulae" end="lead"(CH3(CH2)x)qN ⊕(R4)m--(CH2)zLHQ ⊖ (III)description="In-line Formulae" end="tail" wherein: m is 1 or 2; q=1 or 2 provided that m+q=3; x is 6 to 20; z is 2-10; L is O, S, NR5 or NH; where R5 is C1-4 alkyl or benzyl; each R4 is independently C1-4 alkyl, phenyl or C6-8 aralkyl; and Q⊖ is halogen, alkyl sulfate, or carboxylate, sulfonate, sulfate, phosphonate or phosphate.