IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0821442
(2004-04-09)
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등록번호 |
US-7470124
(2008-12-30)
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발명자
/ 주소 |
|
출원인 / 주소 |
- Nomir Medical Technologies, Inc.
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대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
11 인용 특허 :
52 |
초록
▼
A system and process for thermolytic eradication of bacteria and biofilm in the root canal of a human tooth involve an elongated and flexible optical probe and a laser oscillator that provides the probe with low infrared energy. The optical probe is sufficiently long for insertion into substantially
A system and process for thermolytic eradication of bacteria and biofilm in the root canal of a human tooth involve an elongated and flexible optical probe and a laser oscillator that provides the probe with low infrared energy. The optical probe is sufficiently long for insertion into substantially the entire length of the root canal of the tooth. The optical probe causes lateral dispersion of the radiation from the probe throughout the root canal. The radiation is provided at an energy density and for a period of time that are necessary to selectively target bacteria and live biofilm in the dentinal tubules of an entire root canal system, at once, thereby (1) inhibiting creation of a blackbody "hot tip", and (2) inducing laser interstitial thermotherapy (LITT) within the root-canal space.
대표청구항
▼
What is claimed is: 1. A system for the thermolytic eradication of microorganisms and biofilm in the root canal of a human tooth, said system comprising an elongated and flexible optical probe, a laser oscillator communicating with the distal end of said optical probe through at least one optical f
What is claimed is: 1. A system for the thermolytic eradication of microorganisms and biofilm in the root canal of a human tooth, said system comprising an elongated and flexible optical probe, a laser oscillator communicating with the distal end of said optical probe through at least one optical fiber, a power supply operatively connected to said laser oscillator, and a control operatively connected to said power supply and said laser oscillator; (a) said optical probe being composed of a member of the class consisting of sapphire and zirconium, and having an optically diffusive surface dispersing optical energy throughout 360�� laterally of said optical probe and along the entire length of said optical probe; (b) said optical fiber ranging in diameter between 400 to 1000 μm; (c) said optical probe ranging in diameter from ISO 20 to ISO 70; (d) said laser oscillator generating radiation in two near infrared wavelengths including about 870 nm and 930 nm, respectively; (e) said optical fiber being operatively connected between said laser oscillator and an ingress at the proximal end of said optical probe; (f) said optical probe being sufficiently long for insertion into substantially the entire length of the root canal of said tooth; (g) said optical probe causing lateral dispersion of said radiation from said probe throughout said root canal; and (h) said control being configured and arranged for energizing said laser oscillator for disperation of said radiation at an energy density and for a period of time sufficent to thermolyze said microorganisms and said biofilm in said root canal. 2. The system of claim 1, wherein said period of time is sufficent to destroy pathogenic microorganisms in said root canal. 3. The system of claim 1, wherein said laser oscillator is a diode, and said radiation is continuous mode radiation. 4. The system of claim 1, wherein said laser oscillator is a diode, and said radiation is gated continuous mode radiation. 5. The system of claim 1, wherein said laser oscillator is configured such that said radiation emitted as pulsed mode radiation. 6. A process for treatment of the root canal of a human tooth, said process comprising: (a) preliminary removal of bacteria and biofilm from the entire elongated space of said root canal; (b) debridement of said entire elongated space; (c) insertion of an elongated optical probe into said entire elongated space; (d) transmission of low infrared radiation of two wavelengths including about 870 nm and 930 nm, respectively, longitudinally into the entire length of said optical probe and laterally through the surface of said elongated probe to the surface of said root canal defining said space, and through the dentinal tubules adjoining said root canal space; (e) said transmission being of sufficient energy density and sufficient time duration to thermolyze said biofilm and destroy remnants of said bacteria and adjacent to said root canal; and (g) obturation of said space with an apical seal. 7. The process of claim 6, wherein said optical probe is composed of a member of the class consisting of sapphire and ziconium. 8. The process of claim 6, wherein said optical probe has an optically diffusive surface dispersing optical energy throughout 360�� laterally of said optical probe and along the entire length of said optical probe. 9. The process of claim 6, wherein said radiation is transmitted from said laser to said probe via at least one optical fiber ranging in diameter between 400 to 1000 μm. 10. The process of claim 6, wherein said optical probe ranges in diameter from ISO 20 to ISO 70. 11. The process of claim 6, wherein said laser oscillator generates radiation at duel wavelengths including 780 nm and 930 nm, respectively. 12. A process for treatment of an infection in the root canal of a human tooth, said process comprising: (a) mechanical and chemical removal of bacteria and biofilm from the elongated space of said root canal; (b) mechanical shaping of said elongated space; (c) insertion of an elongated optical probe into said elongated space; (d) transmission of low infrared radiation longitudinally into the entire length of said optical probe and laterally through the surface of said elongated probe to the surface of said root canal defining said space; (e) said transmission being of sufficient energy density and sufficient time duraiton to destroy remnants of said bacteria and biofilm in and adjacent to said root canal; and (f) obturation of said space with an apical seal; (g) said optical probe being composed of a member of the class consisting of sapphire and zirconium; (h) said optical probe having an optically diffusive surface dispersing optical energy throughout 360�� laterally of said optical probe and along substantially the entire lenghth of said optical probe; (i) said radiation being transmitted from said laser to said probe via at least one optical fiber ranging in diameter between 400 to 1000 μm; (j) said optical probe ranging in diameter from ISO 20 to ISO 70; and (k) said laser oscillator being configured and arranged for generating radiatoion in two near infrared wavelengths including about 870 nm to 930 nm, respectively. 13. The process of claim 12, wherein the infection includes Fusobacterium. 14. The process of claim 12, wherein the infection includes Peptostreptococcus. 15. The process of claim 12, wherein the infection includes Eubacterium. 16. The process of claim 12, wherein the infection includes Prevotella. 17. The process of claim 12, wherein the infection includes Lactobacillus. 18. The process of claim 12, wherein the infection includes Streptococcus. 19. The process of claim 12, wherein the infection includes Bacteroides. 20. The process of claim 12, wherein the infection includes Enterococcus. 21. The process of claim 12, wherein the infection includes Actinomyces. 22. The process of claim 12, wherein the infection includes Propionibacterium. 23. A system for creating a photodamage effect for the eradicaition of microorganisms and biofilm that can be applied for the treatment of a root canal of a human tooth, said system comprising an elongated and flexible optical probe, a laser oscillator communicating with the distal end of said optical probe through at least one optical fiber, a power supply operatively connected to said laser oscillator, and a control operatively connected to said power supply and said laser oscillator; (a) said optical probe being composed of a member of the class consisting of sapphire and zirconium, and having an optically diffusive surface dispersing optical energy throughout 360�� laterally of said optical probe and along the entire length of said optical probe; (b) said optical fiber ranging in diameter between 400 to 1000 μm; (c) said optical probe ranging in diameter from ISO 20 to ISO 70; (d) said laser oscillator generating radiation at two near infrared wavelengths including about 870 nm and 930 nm, respectively; (e) said optical fiber being operatively connected between said laser oscillator and an ingress at the proximal end of said optical probe; (f) said optical probe being sufficiently long for insertion into substantially the entire length ot the root canal of said tooth; (g) said optical probe causing lateral dispersion of said radiation from said probe throughout said root canal; and (h) said control being configured and arranged for energizing said laser oscillator for dispersion of said radiation at an energy density and for a period of time sufficient to produce a desired photodamage effect in said microorganisms and said biofilm. 24. The system of claim 23, wherein said period of time is suficient to destroy pathogenic microorganisms in said root canal. 25. The system of claim 23, wherein said laser oscillator is a diode, and said radiation is continuous mode radiation. 26. The system of claim 23, wherein said laser oscillator is a diode, and said radiation is gated continuous mode radiation. 27. The system of claim 23, wherein said laser oscillator is configured such that said radiation emitted as pulsed mode radiation. 28. A process for treatment of the root canal of a human tooth, said process comprising: (a) preliminary removal of bacteria and biofilm from the entire elongated space of said root canal; (b) debridement of said entire elongated space; (c) insertion of an elongated optical probe into said entire elongated space; (d) transmission of low infrared radiation at two wavelengths including about 870 nm and 930 nm, respectively, longitudinally into the entire length of said optical probe and laterally through the surface of said elongated probe to the surface of said root canal defining said space, and through the dentinal tubules adjoining said root canal space; (e) said transmission being of sufficient energy density and sufficient time duration to produce a desired photodamage effect in said biofilm and destroy remnants of said bacteria in and adjacent to aid root canal; and (g) obturation of said space with an apical seal. 29. The process of claim 28, wherein said optical probe is composed of a member of the class consisting of sapphire and zirconium. 30. The process of claim 28, wherein said optical probe has an opticall diffusive surface dispersing optical energy throughout 360�� laterally of said optical probe and along the entire length of said optical probe. 31. The process of claim 28, wherein said radiation is transmitted from said laser to said probe via at least one optical fiber ranging in diameter between 400 to 1000 μm. 32. The process of claim 28, wherein said optical probe ranges in diameter from ISO 20 to ISO 70.
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