$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

4-(2-Fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D)pyrimidine in the treatment of functional bowel disorder 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/497
  • A61K-031/4965
  • C07D-471/04
  • C07D-471/00
  • C07D-237/00
  • A01N-043/54
  • A01N-043/48
출원번호 US-0519594 (2003-07-09)
등록번호 US-7470690 (2008-12-30)
우선권정보 GB-0216027.3(2002-07-10); GB-0304648.9(2003-02-23)
국제출원번호 PCT/GB03/002974 (2003-07-09)
§371/§102 date 20041228 (20041228)
국제공개번호 WO04/004734 (2004-01-15)
발명자 / 주소
  • Cavalla,David
  • Gristwood,Robert William
출원인 / 주소
  • Dynogen Pharmaceuticals, Inc.
대리인 / 주소
    Hamilton, Brook, Smith & Reynolds, P.C.
인용정보 피인용 횟수 : 0  인용 특허 : 41

초록

Use of 4-(2-Fluorophenyl)-6-Methyl-2-(1-Piperazinyl)Thieno[2,3-D]Pyrimidine or a salt thereof for the manufacture of a medicament for the treatment of functional bowel disorder.

대표청구항

The invention claimed is: 1. A method for the treatment of an irritable bowel syndrome selected from diarrhea-predominant irritable bowel syndrome, alternating constipation/diarrhea bowel syndrome, and constipation-predominant irritable bowel syndrome wherein said method comprises orally administer

이 특허에 인용된 특허 (41)

  1. Kato Shiro,JPX ; Hirokawa Yoshimi,JPX ; Morie Toshiya,JPX ; Harada Hiroshi,JPX ; Yoshida Naoyuki,JPX, (R)-5-bromo-N-(1-ethyl-4-methylhexahydr o-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridinecarboxamide, proces.
  2. Gerd Steiner DE; Uta Dullweber DE; Dorothea Starck DE; Alfred Bach DE; Karsten Wicke DE; Hans-Jurgen Teschendorf DE; Francisco-Javier Garcia-Ladona DE; Franz Emling DE, 3-substituted 3,4,5,7-tetrahedropyrrolo[3',4':4,5]thieno-[2,3-d]pyrimidine derivatives, their preparation and use.
  3. Oakley Nigel R. (Cambridge GB2) Coates Ian H. (Hertford GB2) North Peter C. (Royston GB2) Oxford Alexander W. (Royston GB2), 5-HT3 receptor antagonists for the treatment of autism.
  4. Kelley James Leroy ; Musso David Lee, Amide derivatives and their therapeutic use.
  5. McInally Thomas,GBX ; Tinker Alan,GBX, Aminopyrimidine derivatives, processes for their preparation, compositions containing them and their use as pharmaceuticals.
  6. Bonnacker Ingo,DEX ; Koehn Hartmut,DEX ; Kristen Gerhard,DEX ; Reichel Christine,DEX, Cilansetron pharmaceutical preparation stabilized against racemization.
  7. Gidda Jaswant S. (Carmel IN) Schaus John M. (Zionsville IN), Isoxazole derivatives for the treatment of irritable bowel syndrome.
  8. Cautreels, Werner L. M.; Steinborn, Claus Rudolf; Krause, Heinz Guenter; Caras, Steven David; Biesheuvel, Egbertus Hendrikus Evert; Plekkenpol, Albertus Hermannus Dirk, Medicament containing cilansetron for the treatment of non-obstipative male irritable bowel syndrome patients.
  9. Mangel Allen Wayne ; Northcutt Allison Ruth, Medicaments for the treatment of non-constipated female irritable bowel syndrome.
  10. Crain Stanley M. ; Shen Ke-fei ; Fleischner Gerald M., Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists.
  11. Raymond J. Bergeron, Jr., Method and composition for treatment of irritable bowel disease.
  12. Rubin Walter ; Dave Bhavin, Method for alleviation of lower gastrointestinal disorders in a human patient.
  13. Eeckhout Christian (Bad Pyrmont DEX) Preuschoff Ulf (Uelzen DEX) David Samuel (Hanover DEX), Method of treating colon disturbances with pharmaceutical compositions containing imidazol-1-yl compounds.
  14. Landau,Steven B.; Miller,Cheryl L.; Thor,Karl B., Method of treating nausea, vomiting, retching or any combination thereof.
  15. Eeckhout Christian,DEX ; Sann Holger,DEX, Method of treating or inhibiting functional disturbances or illnesses of the lower intestinal tracts, particularly abdominal visceral pain which accompanies them.
  16. Erik H. F. Wong ; Saeeduddin Ahmed ; Robert C. Marshall ; Robert McArthur ; Duncan P. Taylor ; Lars Birgerson ; Pasquale Cetera, Method of treating or preventing chronic pain with a highly selective norepinephrine reuptake inhibitor.
  17. Lin Henry C., Methods and compositions for improving digestion and absorption in the small intestine.
  18. Lin, Henry C., Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia.
  19. Young James W., Methods for treating behavioral and other disorders using optically pure R(+) ondansetron.
  20. Young James W. (Palo Alto CA), Methods for treating emesis and nausea using optically pure R(+) ondansetron.
  21. Allen Wayne Mangel ; Allison Ruth Northcutt, Methods for treating irritable bowel syndrome.
  22. Mangel, Allen Wayne; Northcutt, Allison Ruth, Methods for treating irritable bowel syndrome.
  23. Fairbanks Carolyn A. ; Wilcox George L. ; Stone Laura S.,CAX ; Kitto Kelley F., Methods of using moxonidine to inhibit nociceptive pain.
  24. Thomas P. Jerussi ; Chrisantha H. Senanayake ; Qun K. Fang, Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction.
  25. Gonsalves Susan F. (Stonington CT), NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis.
  26. Haeck Hans H. (Weesp NLX) Hamminga Derk (Weesp NLX) Van Wijngaarden Ineke (Weesp NLX) Wouters Wouter (Weesp NLX), New anellated indole derivatives.
  27. Sanger Gareth J. (Harlow GB2) Marr Helen E. (Harlow GB2), Novel treatment.
  28. Davies Huw M. L. ; Childers Steven R. ; Bennett Barbara, Process for blocking 5-HT and dopamine uptake with biologically active tropane derivatives.
  29. van der Meij Paulus F. C. (Weesp NLX) Verbeek Jan-Maarten (Weesp NLX), Process for the preparation of enantiomerically pure imidazolyl compounds.
  30. Lothar Farber DE; Wolfgang Muller CH; Thomas Stratz DE, Systemic use of 5-HT3 receptor antagonists against rheumatic inflammatory processes.
  31. Ninomiya Kunihiro (Machida JPX) Nitta Issei (Machida JPX) Tobe Akihiro (Yokohama JPX) Egawa Mitsuo (Machida JPX) Kikumoto Ryoji (Machida JPX), Thieno[2,3-d]pyrimidine derivatives and salts thereof.
  32. Maruyama Akira (Kashima JPX) Ogawa Shigeru (Machida JPX) Yamazaki Satoshi (Sagamihara JPX) Tobe Akihiro (Yokohama JPX), Thieno[3,2-b]pyridine derivatives.
  33. Wilfried Fischer DE; Axel Stierle DE, Transdermal systems for release of 5-HT3 receptor antagonists and their use in anti-emetic treatment.
  34. Cari Loder GB; David F. Horrobin GB, Treatment of fatigue, head injury and stroke.
  35. Fairbanks Carolyn A. ; Wilcox George L. ; Laughin Tinna M., Treatment of neuropathic pain.
  36. Cavalla,David; Gristwood,Robert William, Use of 4-(2-Flurophenyl)-6-methyl-2-(1-piperazinyl)thieno(2,3-D)-pyrimidine for treating of urinary incontinence.
  37. Azcona Alberto E. (Basel CHX) Taylor Pamela (Basel CHX), Use of 5-HT3 receptor antagonists in treating panic disorders or obsessive compulsive disorders.
  38. Megens Antonius A. H. P.,BEX, Use of 5HT3, antagonists for promoting intestinal lavage.
  39. Meulemans Ann Louise Gabrielle,BEX ; Bosmans Jean-Paul Rene Marie Andre,BEX, Use of 5HT4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors.
  40. Sawynok Jana,CAX ; Esser Mike,CAX ; Reid Allison,CAX, Use of antidepressants for local analgesia.
  41. Muller Wolfgang,CHX ; Stratz Thomas,DEX, Use of serotonin antagonists for treating fibromyalgia.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로