Device and method for drug delivery to animals
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-031/00
A61M-037/00
A61M-005/14
A61M-005/00
출원번호
US-0612484
(2003-07-02)
등록번호
US-7488309
(2009-02-10)
발명자
/ 주소
Kissinger,Candice B.
Hampsch,James M.
Bougher,Joseph A.
출원인 / 주소
Bioanalytical Systems, Inc.
대리인 / 주소
Ice Miller LLP
인용정보
피인용 횟수 :
5인용 특허 :
18
초록▼
A drug delivery device that utilizes a fluid subsystem with a switching device to deliver multiple drugs to an animal without causing contamination. The fluid subsystem can further comprise disposable syringes, fluid reservoirs, disposable tubing and a catheter. In the embodiments that utilize multi
A drug delivery device that utilizes a fluid subsystem with a switching device to deliver multiple drugs to an animal without causing contamination. The fluid subsystem can further comprise disposable syringes, fluid reservoirs, disposable tubing and a catheter. In the embodiments that utilize multiple disposable syringes, the drug delivery device allows a user to deliver multiple drugs to an animal through a catheter without contaminating the switching devices that control the flow of fluid. The drug delivery device can further utilize a controller to control the switching devices and a controller and syringe pumps to control the operation of the syringes.
대표청구항▼
We claim: 1. A drug delivery device for animals, the device comprising: a. at least a first syringe coupled with a first tube connector and a second syringe coupled with a second tube connector; b. a plurality of disposable tubes, including at least a first tube, a second tube, a third tube and a f
We claim: 1. A drug delivery device for animals, the device comprising: a. at least a first syringe coupled with a first tube connector and a second syringe coupled with a second tube connector; b. a plurality of disposable tubes, including at least a first tube, a second tube, a third tube and a fourth tube; c. at least one catheter adapted to be placed into an animal; d. at least a first and second pinch valve, each pinch valve having a first position and a second position, the first position and the second position each configured to receive one of the plurality of disposable tubes therethrough and for control of fluid flowing through the plurality of disposable tubes without being in fluid communication with the fluid; e. a first reservoir containing a first fluid, wherein the first tube passes through the first position of the first pinch valve and is configured to allow the first fluid to flow between the first reservoir and the first syringe through the first tube connector; f. at least one second reservoir containing a drug fluid, wherein the second tube passes through the first position of the second pinch valve and is configured to allow the drug fluid to flow between the second reservoir and the second syringe through the second tube connector; and g. a third tube connector in fluid communication with the at least one catheter, wherein the third tube passes through the second position of the second pinch valve and is configured to allow the drug fluid to flow between the second syringe and the catheter through the third tube connector, and wherein the fourth tube passes through the second position of the first pinch valve and is configured to allow the first fluid to flow from the first syringe to the catheter through the third tube connector. 2. The drug delivery device of claim 1, further comprising a first and second syringe pump, wherein the first syringe pump is associated with the first syringe and the second syringe pump is associated with the second syringe, such that the first and second syringe pumps operate each of the first and second syringes independently of each other. 3. The drug delivery device of claim 2, further comprising a third syringe. 4. The drug delivery device of claim 3, further comprising a third syringe pump operably connected to the third syringe. 5. The drug delivery device of claim 4, further comprising a third reservoir. 6. The drug delivery device of claim 5, further comprising a fourth tube connector in fluid communication with the third reservoir and the third syringe, a fifth tube connector in fluid communication with the at least one catheter and the third syringe and a third pinch valve, wherein a fifth tube passes through the first position of the third pinch valve and is configured to allow fluid to flow from the third reservoir to the third syringe through the fourth tube connector, and wherein a sixth tube passes through the second position of the third pinch valve and is configured to allow fluid to flow from the third syringe to the at least one catheter through the fifth tube connector. 7. The drug delivery device of claim 6, wherein the plurality of disposable tubes further comprises a system outlet that connects the fifth tube connector to the at least one catheter. 8. The drug delivery device of claim 7, wherein the at least one catheter comprises a catheter connected to the system outlet by a catheter outlet. 9. The drug delivery device of claim 8, further comprising a fourth pinch valve with its first position containing the catheter outlet. 10. The drug delivery device of claim 9, further comprising a waste outlet that is connected to the system outlet and that is contained by the second position of the fourth pinch valve, so that when the first position of the fourth pinch valve is open, the second position of the fourth pinch valve is closed and fluid is allowed to pass between the system outlet and the catheter outlet, and when the second position of the fourth pinch valve is open, the first position of the fourth valve is closed and fluid is allowed to pass between the system outlet and the waste outlet. 11. The drug delivery device of claim 10, wherein the controller is operably connected to the first, second, and third syringe pumps and is operably connected to the first, second, third, and fourth pinch valves, such that the controller automatically controls the movement of the first, second, and third syringe pumps and controls the movement of the first and second positions of each of the first, second, third, and fourth pinch valves. 12. The drug delivery device of claim 4, wherein the first reservoir contains a drug. 13. The drug delivery device of claim 4, wherein the first reservoir contains a saline solution. 14. The drug delivery device of claim 1, further comprising a controller that is operably connected to the first and second syringes and operably connected to the at least one pinch valve, wherein the controller is capable of operating the first and second syringes and the pinch valves to prime the at least one catheter, to flush the plurality of disposable tubes and/or the at least one catheter, and to deliver the first fluid or drug fluid to the animal. 15. A drug delivery device for animals comprising a housing that holds: a. at least a first, second and third tube connector; b. at least a first and second syringe inlet tube, each with a first end and a second end, wherein the second end of the first syringe inlet tube is connected to the first tube connector and the second end of the second syringe inlet tube is connected to the second tube connector; c. at least a first and second syringe, the first and second syringes being connected to the first and second tube connector, respectively; d. at least a first and second syringe outlet tube, each with a first end and a second end, wherein the first end of the first syringe outlet tube is connected to the first tube connector and the second end of the first syringe outlet tube is connected to the third tube connector and wherein the first end of the second syringe outlet tube is connected to the second tube connector and the second end of the second syringe outlet tube is connected to the third tube connector; e. at least a first and second reservoir wherein the first reservoir is connected to the first end of the first syringe inlet tube and the second reservoir is connected to the first end of the second syringe inlet tube; f. at least one catheter adapted to be placed into an animal; g. a system outlet tube with a first end and a second end, wherein the first end of the system outlet tube is connected to the catheter and the second end of the outlet tube is connected to the third tube connector; h. at least a first and second pinch valve, the first pinch valve having a first position through which the first syringe inlet tube passes and a second position through which the first syringe outlet tube passes and the second pinch valve having a first position through which the second syringe inlet tube passes and a second position through which the second syringe outlet tube passes, wherein in each of the first and second pinch valves only one of the first or second positions opens while the other position remains closed, without being in communication with the fluid, in order to control fluid passing through the syringe inlet tubes, the syringe outlet tubes, the system outlet tube and the catheter; and i. electronic circuitry that controls the opening and closing of the first and second positions of each of the first and second valves, such that the electronic circuitry operates to prime the at least one catheter, flush the system outlet tube and/or the at least one catheter and deliver fluid to the animal. 16. The drug delivery device of claim 15 wherein the first and second syringe inlet tubes, the first and second syringe outlet tubes, and the system outlet tubes are all disposable tubes. 17. The drug delivery device of claim 15 further comprising a fourth tube connector connected to the first end of the system outlet, a waste tube with a first end and a second end, wherein the first end is connected to the fourth tube connector, and a catheter inlet tube with a first end connected to the fourth tube connector and the second end connected to the catheter. 18. The drug delivery device of claim 17 further comprising a third pinch valve with a first position through which the catheter inlet tube passes and a second position through which the waste tube passes, wherein only one of the first or second position opens while the other position remains closed in order to allow fluid to either pass through the waste tube or catheter inlet tube.
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이 특허에 인용된 특허 (18)
Wallach Mark (New York NY), Animal injector apparatus.
Reilly, David M.; Hirschman, Alan D.; Griffiths, David M.; Crookston, Currie, Delivery methods, systems and components for use with hazardous pharmaceutical substances.
Epstein Paul (Brookline MA) Petschek Harry (Lexington MA) LaWhite Eric (South Royalton VT) Strohl Clair (Norfolk MA) Coyne Henry (Framingham MA) Kaleskas Edward (Jefferson MA) Adaniya George (Swampsc, Infusion system having plural fluid input ports and at least one patient output port.
Halls Justin A. T. (147 Briar Road Kingswood ; Garston ; Watford ; Herts GB2) Hawes David W. (40 Leighfield Mortimer ; Reading ; Berks GB2) Wolff Heinz S. (53 Meadway London NW11 GB2) Vahrman Richard, Method and apparatus for taking samples from or administering medication to a patient.
Kissinger Candice B. ; Bohs Curtis E. ; Evans Donnie A. ; Schmidt William J. ; Peters Scott R. ; Gunaratna W. Gamini ; Hampsch James M., Movement-response system for conducting tests on freely-moving animals.
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