초록 ▼

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and men

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.

대표청구항 ▼

What is claimed is: 1. A method for preparing a physiologically compatible film, said method comprising: mixing at least one water soluble film former and at least one stabilizing agent selected from the group consisting of xanthan gum, locust bean gum, carrageenan, guar gum and mixtures thereof to

What is claimed is: 1. A method for preparing a physiologically compatible film, said method comprising: mixing at least one water soluble film former and at least one stabilizing agent selected from the group consisting of xanthan gum, locust bean gum, carrageenan, guar gum and mixtures thereof to provide a film-forming mixture; providing water soluble ingredients capable of forming electrolytes when dissolved in water; dissolving the water-soluble ingredients in water to provide an electrolyte containing aqueous solution; combining said film-forming mixture and the aqueous solution to provide a hydrated polymer gel; mixing oils to form an oil mixture that comprises at least one essential oil selected from the group consisting of thymol, methyl salicylate, eucalyptol, and menthol wherein the total amount of the oils in the oil mixture is at least about 5 wt % of the total weight of ingredients; adding said oil mixture to said hydrated polymer gel and mixing to provide a uniform gel; casting the uniform gel on a substrate; and drying the cast gel to provide said film. 2. The method according to claim 1, wherein at least one surfactant is mixed into said oil mixture. 3. The method according to claim 2, wherein said total amount of oils is at least about 15 wt %. 4. The method according to claim 1, wherein said drying is conducted until said film has a moisture content of about 3 wt % to about 8 wt %. 5. The method according to claim 1, wherein, prior to being combined with said aqueous solution, said film-forming mixture is hydrated with water at a temperature of about 25 to about 50�� C. and subsequently chilled to a temperature of about 4 to about 30�� C. for about 2 to 48 hours. 6. The method according to claim 1, wherein said film-forming mixture is a powder, which is directly combined with said aqueous solution. 7. The method according to claim 6, wherein said hydrated polymer gel is formed without heating. 8. The method according to claim 7, wherein said hydrated polymer gel is stirred at room temperature for about 2 to about 48 hours. 9. The method according to claim 8, wherein said oil mixture is prepared by mixing thymol and menthol in a flavor oil, and subsequently adding methyl salicylate and eucalyptol. 10. A non-self-adhering film produced according to the method of claim 1. 11. The method according to claim 1, wherein the water soluble film former is selected from the group consisting of pullulan, hydroxyproplymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, polyvinyl pyrrolidone, carboxymethyl cellulose, polyvinyl alcohol, sodium alginate, polyethylene glycol, tragacanth gum, guar gum, acacia gum, arabic gum, polyacrylic acid, methylmethacrylate copolymer, carboxyvinyl polymer, amylose, high amylose starch, hydroxypropylated high amylose starch, dextrin, pectin, chitin, chitosan, levan, elsinan, collagen, gelatin, zein, gluten, soy protein isolate, whey protein isolate, casein and mixtures thereof. 12. The method according to claim 11, wherein said water soluble polymer is pullulan.