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Immunoassay probe 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/553
  • G01N-033/551
  • G01N-021/00
출원번호 UP-0411441 (2003-04-10)
등록번호 US-7514270 (2009-07-01)
발명자 / 주소
  • Achter, Eugene K.
  • Schroeder, Hartmut Richard
  • Trotta, Stephen S.
출원인 / 주소
  • Instrumentation Laboratory Company
대리인 / 주소
    K&L Gates LLP
인용정보 피인용 횟수 : 0  인용 특허 : 216

초록 ▼

An analytical instrument for the immobilization of antigens to be detected in an immunoassay using mangetizable beads. The instrument includes a probe containing magnetizable particles and a plurality of magnetic devices for applying a magnetic field gradient to the particles in the probe reservoir.

대표청구항 ▼

What is claimed is: 1. A device for manipulating a magnetizable particle suspended in a solution, comprising: a first magnet; a second magnet; and a probe for holding and transporting said magnetizable particle comprising an open top and an open bottom, wherein said probe is transportable through a

이 특허에 인용된 특허 (216)

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  137. Christensen Dale A. (both c/o Camas Diagnostic Company ; 1313 Fifth St. SE. Minneapolis MN 55414) Nash Peter (both c/o Camas Diagnostic Company ; 1313 Fifth St. SE. Minneapolis MN 55414), Method and kit for diagnosis of diseases.
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  138. Jukka Tuunanen FI, Method and means for magnetic particle specific binding assay.
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  139. Tuunanen Jukka,FIX, Method and means for magnetic particle specific binding assay.
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  140. Bird Frederick John (Surrey CAX) Dominelli Nicola (Coquitlam CAX) Ashby Gordon R. (Surrey CAX), Method and reagent kit for determining paper degredation in transformers.
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  141. Fujino Naohiko,JPX ; Karino Isamu,JPX ; Ohmori Masashi,JPX ; Yasutake Masatoshi,JPX ; Wakiyama Shigeru,JPX, Method for analyzing minute foreign substance elements.
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  142. Lee Ching-Cherng (Newark DE) Davis James E. (Wilmington DE), Method for automatically processing magnetic solid phase reagents.
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  143. James Samsoondar CA, Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes.
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  144. Fujiwara Koichi (Mito JPX) Mizutani ; deceased Hiromichi (late of Tokyo JPX by Hiroko Mizutani ; Tokyo ; legal representative), Method for collecting and preparing specimens for immune reactions.
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  145. Katopodis Nonda (Stamford CT), Method for determining lipid bound sialic acid in plasma.
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  146. Katopodis Nonda (Stamford CT), Method for determining lipid bound sialic acid in whole blood.
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  147. Katopodis Nonda (Stamford CT), Method for determining sialic acid in plasma.
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  148. Khan ; Waheed N., Method for differential diagnosis of meningitis with a limulus lysate test.
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  149. Takekawa Hiroshi (Sagamihara JPX) Yamada Takashi (Sagamihara JPX), Method for effecting heterogeneous immunological analysis.
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  150. Wang Yuzhou (Wayne PA) Tang Weixin (Landsdale PA) Cronin William J. (Matawan NJ) Liberti Paul A. (Huntingdon Valley PA), Method for magnetic separation featuring magnetic particles in a multi-phase system.
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  151. Iqbal W. Siddiqi, Method for mixing and separation employing magnetic particles.
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  152. Katoot Mohammad W., Method for modifying the surface of an object.
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  153. Oberhardt Bruce J. (Raleigh NC), Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic pa.
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  154. Sterman, Martin D.; Lituri, Paul; Stelter, Richard E., Method for separating magnetized substances from a solution.
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  155. Cassaday Michael M., Method for separation of components in a biochemical reaction utilizing a combination of magnetic and centrifugal processes.
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  156. Tajima Hideji,JPX, Method for sucking/determining liquid and pipetting device driven and controlled according to method.
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  157. Tajima Hideji,JPX, Method for sucking/determining liquid and pipetting device driven and controlled according to method.
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  158. Knobel Rolf (Rotkreuz CHX), Method for suspending particles.
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  159. Zimmermann Joseph J. (Elm Grove WI) Lewis N. Tracey (Brossard CAX) Heft Robert A. (Ville St. Laurent CAX), Method for the enzymatic neutralization of heparin.
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  160. Tajima Hideji,JPX, Method for treating biopolymers, microorganisms or materials by using more than one type of magnetic particles.
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  161. William David Dunfee ; Kerry Lynn Miller, Method for verifying the integrity of a fluid transfer.
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  162. Chuang-Chun Chueh TW, Method of allophycocyanin inhibition of enterovirus and influenza virus reproduction resulting in cytopathic effect.
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  163. Bienhaus Gerhard,DEX ; Stolz Burkhard,DEX ; Schubert Ulrich,DEX, Method of magnetically separating liquid components.
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  164. Mahant Vijay ; Doneen Byron, Method using an apparatus for separation of biological fluids.
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  165. Liberti Paul A. (Huntingdon Valley PA) Wang Yozhou (Media PA), Methods and devices for manipulation of magnetically collected material.
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  166. Miltenyi Stefan (Moitzfeld 60a D-5060 Bergisch Gladbach 1 ; Cologne DEX), Methods and materials for improved high gradient magnetic separation of biological materials.
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  167. Stefan Miltenyi DE, Methods and materials for improved high gradient magnetic separation of biological materials.
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  168. Terstappen Leon W. M. M. ; Liberti Paul A., Methods for biological substance analysis employing internal magnetic gradients separation and an externally-applied transport force.
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  169. Parton Adrian,GBX, Methods of capturing species from liquids and assay procedures.
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  170. Jeffs David H. (Salt Lake City UT) Jessop Paul M. (Salt Lake City UT), Methods of using micro pipette tips.
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  171. Miltenyi, Stefan; Siebenkotten, Gregor; Koester, Mathias, Micro column system.
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  172. Burkovich Robert A. (Newark DE) Lipscomb James H. (Kennett Square PA) Nurse Colin A. (Newark DE) Wong Kin W. (Claymont DE) Zuk Paul J. (Lincoln University PA) Bernstine Robert E. (Chesapeake City MD), Multi-linear automatic apparatus for processing immunoassays.
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  173. Hideji Tajima JP, Multi-vessel container for testing fluids.
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  174. Tajima Hideji,JPX, Multi-vessel container for testing fluids.
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  175. Oxley L. Thomas (Riverwoods IL) Morrisseau Virginia C. (Lindenhurst IL), Multicompartment biological fluid specimen collection bag.
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  176. Hammond Philip W. ; Abrams Ezra S. ; Boles T. Christian ; Muir Andrew R., Multiple sequential polynucleotide displacement reactions for signal amplification and processing.
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  177. Konrad Michael W., Optical detection of position of oligonucleotides on large DNA molecules.
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  178. Hummell, Michael; Pearce, Joseph R., Optical disc adhesive label applicator.
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  179. Olesen S.o slashed.ren-Peter,DKX ; Christophersen Palle,DKX, Patch clamp apparatus and technique having high throughput and low fluid volume requirements.
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  180. Takeshi Taguchi JP; Mitsuo Hiramatsu JP, Pipette adapter, absorbance measuring pipette, tip, absorbance measuring apparatus, and absorbance measuring.
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  181. Fatches Keith R. (6 Crewe St. Bardwell Park ; New South Wales ; 2207 AUX), Pipette and filter combination.
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  182. Columbus Richard L. (Rochester NY), Pipette and liquid transfer apparatus for dispensing liquid for analysis.
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  183. Arpagaus Renato (Chur CHX) Leyssens Herwig (Tamins CHX), Pipette and pipetting apparatus.
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  184. Tajima Hideji,JPX, Pipette tip.
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  185. Kevin S. Bodner ; Andrew P. Sandham, Pipette-loaded bioassay assembly for detecting molecular or cellular events.
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  186. Berger Richard M. (Midlothian VA), Polyethylene terephthalate sheath/thermoplastic polymer core bicomponent fibers, method of making same and products form.
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  187. Quenin John A. (Rochester NY) Porte Johannes J. (Webster NY), Positively engaged pipette and pipette support.
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  188. Pruss Hans-Dieter (Cologne DEX) Bahrs Ltje-Wilhelm (Halstenbek DEX), Preparation of cheese with ropy lactic acid bacteria.
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  189. Marteau d\Autry Eric (72 ; rue Gambetta 95400 Villiers-le-Bel FRX), Process and device for calibrating a sampling and metering pipette.
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  190. Wand Bruce (Randolph Township ; Morris County NJ), Protective shield for capillary pipette.
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  191. Terstappen Leon W. M. M. ; Liberti Paul A., Quantitative cell analysis methods employing magnetic separation.
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  192. Sucholeiki Irving, Reaction plenum with magnetic separation and/or ultrasonic agitation.
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  193. Horner, Glenn A.; Johnson, Shirley J.; Schneider, Robert E.; Smith, Robert J.; Tseo, Gus, Reaction receptacle apparatus.
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  194. LaBudde, Edward V.; Wilson, Anthony D., Reagent dispensing valve.
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  195. Liberti Paul A. (Churchville PA) Pino Maria A. (Philadelphia PA), Resuspendable coated magnetic particles and stable magnetic particle suspensions.
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  196. Zabetakis George (Bethel CT) Gherson Paul G. (Yorktown Heights NY), Reversible direction capsule chemistry sample liquid analysis system and method.
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  197. Leopardi Francesco (Milan ITX) Paoletti Sergio (Milan ITX) Salome Daniele P. (Milan ITX), Safety closing device for biological liquid containers.
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  198. D'Angelo Joseph P., Saliva collector with an aspirating pipette.
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  199. Taku Sakazume JP; Hiroshi Mitsumaki JP, Sample processing system.
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  200. Jukka Tuunanen FI, Separation device for microparticles involving a magnetic rod.
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  201. Tuunanen Jukka,FIX, Separation of magnetic microparticles involving a preconcentration step.
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  202. Torti Victor A. ; Zier Robert H. ; Boucher Jean-Paul G., Small sample volume displacement pipette tips.
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  203. Rampal Jang B. (Fremont CA) Harbaugh Jon F. (Los Altos CA), Solid phase system for sequential reactions.
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  204. Hansen, Timothy Roy; Thomas, Bradley Scott; Bianco, John Joseph; Collis, Matthew P., System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample.
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  205. Svetlana Velkovska ; Kerwin Ng ; Haim Kedar, System and method for single or multiple bead distribution with an adjustable capillary.
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  206. Reichler Allen S. (Owing Mills MD) Antol David J. (Baldwin MD) Lamos Michael L. (Westminster MD) Bourdelle Peter A. (Glen Rock PA) Hildebrand Scott D. (Red Lion PA), System for nucleic acid based diagnostic assay.
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  207. Cork William H. (Brecksville OH), System for optically interrogating liquid samples and for withdrawing selected sample portions.
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  208. Bienhaus Gerhard,DEX ; Schubert Ulrich,DEX ; Kolb Uwe,DEX ; Stolz Burkhard,DEX ; Pasch Manfred,DEX, System for releasing and isolating nucleic acids.
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  209. Becker Thomas,DEX ; Koster Hubert ; Cantor Charles, Systems and methods for performing reactions in an unsealed environment.
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  210. Gavin Robert M. ; Sugarman Jeffrey H. ; Kedar Haim ; Chan Sam, Systems for arraying beads.
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  211. Pellet Regis J. ; Bartley ; Jr. Leonard S. ; Van de Ven Paul M. V., Test kit for measuring the level of carboxylate anion in engine coolant.
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  212. Knesel ; Jr. Ernest A. (Greensboro NC) Shoemaker Daniel R. (Elon College NC) Fansler David V. (Graham NC), Test tube filter/dispenser apparatus and method.
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  213. Bochner Barry (Alameda CA), Testing device for liquid and liquid suspended samples.
    상세보기
  214. Korpela Matti,FIX ; Tuunanen Jukka,FIX, Two-stage separation method.
    상세보기
  215. Roelant Chris,BEX, Use of porphyrins as a universal label.
    상세보기
  216. Tuunanen Jukka (Helsinki FIX) Narvanen Ale (Helsinki FIX) Geysen Mario (Clayton AUX), Washing device.
    상세보기

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