Apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment of this invention, the apparatus includes a therapeutic guidewire and at least one optical fiber dispos
Apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment of this invention, the apparatus includes a therapeutic guidewire and at least one optical fiber disposed through the therapeutic guidewire, the optical fiber capable of providing diagnostic information before, during, and after the therapeutic treatment. In an embodiment, diagnostic information includes vessel and blood characteristics such as hemodynamic characteristics, hematological parameters related to blood and blood components, and thermal parameters of the vasculature.
대표청구항▼
We claim: 1. An apparatus configured for being introduced into a patient's anatomy comprising: a therapeutic hollow guidewire having a high strength proximal core section, a flexible distal core section, a lumen extending within the proximal and distal core sections, and a distal end comprising a d
We claim: 1. An apparatus configured for being introduced into a patient's anatomy comprising: a therapeutic hollow guidewire having a high strength proximal core section, a flexible distal core section, a lumen extending within the proximal and distal core sections, and a distal end comprising a distal tip coil bonded to the distal core section and an atraumatic distal tip member bonded to a distal end of the coil; and at least one optical fiber slideably disposed within the lumen of the therapeutic guidewire, having a distal tip which is slidably positionable within the atraumatic distal tip member and which has an optically exposed configuration in which the optical fiber distal tip is in optical contact with the patient's anatomy outside the guidewire from within the distal tip member such that the optical fiber distal tip is configured for light transmission and/or reception so that the optical fiber is configured to sense and transmit diagnostic information from at least one of before, during, and after a therapeutic treatment. 2. The apparatus of claim 1 wherein the apparatus is coupled to a data processing system and the at least one optical fiber is configured to sense vessel and blood characteristics. 3. The apparatus of claim 2 wherein the vessel and blood characteristics are selected from the group consisting of hemodynamic characteristics, hematological parameters related to blood and blood components and thermal parameters of the vasculature. 4. The apparatus of claim 1 wherein the therapeutic guidewire is operatively coupled to a catheter. 5. The apparatus of claim 4 wherein the at least one optical fiber is marked with a radiopaque substance. 6. The apparatus of claim 1, further comprising a polymeric jacket disposed about the distal core section. 7. An apparatus as in claim 1 wherein the optical fiber provides an image of an element from light gathered from the element, the light being conveyed through the optical fiber. 8. An apparatus comprising: a therapeutic hollow guidewire having a high strength proximal core section and flexible distal core section, a coil attached to the distal core section and an atraumatic tip attached to the coil, the therapeutic guidewire configured to operatively receive a treatment device; a polymeric jacket disposed about the distal core section; and at least one optical fiber slideably disposed within the therapeutic hollow guidewire, having a distal tip that extends into said atraumatic tip in which the optical fiber distal tip is in optical contact with the patient's anatomy through the atraumatic tip which is configured for light transmission and/or reception to sense and transmit vessel and blood characteristics. 9. The apparatus of claim 8 wherein the treatment device is selected from the group consisting of intravascular device, intraluminal device, intraductal device and intraorgan device. 10. The apparatus of claim 8 wherein the apparatus is coupled to a data processing system and the vessel and blood characteristics are selected from the group consisting of hemodynamic characteristics, hematological parameters related to blood and blood components and thermal parameters of the vasculature. 11. The apparatus of claim 8 wherein the therapeutic guidewire includes a connecting member coupling the proximal and distal core sections; and an atraumatic distal tip formed at a distal end of the distal core section. 12. The apparatus of claim 11 wherein the atraumatic distal tip includes a clear polymeric material sheath coupled to the distal end of the flexible coil. 13. The apparatus of claim 11 wherein the polymeric jacket is coupled to at least one point along an outer surface of the distal core section, and the atraumatic distal tip is coupled to a distal end of the polymeric jacket. 14. An apparatus as in claim 8 wherein the at least one optical fiber provides an image of an element from light gathered from the element, the light being conveyed through the at least one optical fiber. 15. A system for sensing vessel and blood characteristics, the system comprising: a data processing system; and an apparatus coupled to the data processing system, the apparatus comprising a therapeutic hollow guidewire having a high strength proximal core section and flexible distal core section, a lumen extending within the proximal and distal core sections, and a distal end comprising a distal tip coil bonded to the distal core sections and an atraumatic distal tip member bonded to a distal end of the coil, and at least one optical fiber slidably disposed therein, the optical fiber having a distal tip which has an optically exposed configuration in which the optical fiber distal tip is positioned within said atraumatic distal tip member and in optical contact with the patient's anatomy outside the guidewire, the optical fiber capable to sense vessel and blood characteristics and transmit the sensed vessel and blood characteristics to the data processing system. 16. The system of claim 15 wherein the vessel and blood characteristics are selected from the group consisting of hemodynamic characteristics, hematological parameters related to blood and blood components and thermal parameters of the vasculature. 17. The system of claim 15, further comprising a polymeric jacket disposed about the distal core section. 18. A system as in claim 15 wherein the at least one optical fiber provides an image of an element from light gathered from the element, the light being conveyed through the at least one optical fiber. 19. The system of claim 15 wherein the optical fiber tip is bent away from a centerline of a distal end section of the guidewire. 20. The system of claim 15 wherein an end surface of the optical fiber tip is oriented at an angle relative to a transverse plane perpendicular to a longitudinal axis of the fiber. 21. A method of sensing vessel and blood characteristics, the method comprising: operating a data processing system coupled to a therapeutic hollow guidewire having a lumen, a high strength proximal core section and flexible distal core section having a distal coil capped by an atraumatic distal tip, and at least one optical fiber having a distal tip slideably disposed in the hollow guidewire to be positioned in an optically exposed configuration in which the optical fiber distal tip is in optical contact with the patient's anatomy outside the guidewire from within the atraumatic distal tip of the guidewire such that the optical fiber distal tip is configured for light transmission and/or reception and such that light signals are transmitted to the desired location in the vasculature and reflected light signals are collected by the data processing system; and processing the reflected light signals to provide vessel and blood characteristics. 22. The method of claim 21 wherein the vessel and blood characteristics are selected from the group consisting of hemodynamic characteristics, hematological parameters related to blood and blood components and thermal parameters of the vasculature. 23. A method as in claim 21 wherein the optical fiber provides an image of an element from light gathered from the element, the light being conveyed through the optical fiber. 24. An apparatus configured for being introduced into a patient's anatomy comprising: a) a hollow guidewire having a relatively high strength proximal core section, a relatively flexible distal core section, a lumen extending within the proximal and distal core sections, a distal tip coil on the distal core section, and a clear polymeric distal tip member bonded to a distal end of the coil; and b) at least one optical fiber slidably disposed within the lumen of the guidewire, having a distal tip which is within and surrounded by the clear distal tip member such that the distal tip of the fiber is in optical contact with the patient's anatomy outside the guidewire from within the clear distal tip member and is configured for light transmission and/or reception in the patient's anatomy.
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이 특허에 인용된 특허 (58)
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