[특허]Specific coupling reaction measuring method

Specific coupling reaction measuring method 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	G01N-033/553 G01N-033/551
출원번호	UP-0507011 (2006-08-21)
등록번호	US-7553676 (2009-07-09)
우선권정보	JP-2002-328056(2002-11-12)
발명자 / 주소	Kamei, Akihito Shigetoh, Nobuyuki Kawamura, Tatsurou
출원인 / 주소	Panasonic Corporation
대리인 / 주소	McDermott Will & Emery LLP
인용정보	피인용 횟수 : 0 인용 특허 : 25

초록 ▼

A specific coupling reaction measuring method of this invention for measuring a content of a subject substance in a sample includes the steps of (a) constructing a reaction system including the sample and a magnetic particle on which a specific coupling substance for specifically coupling with the subject substance is immobilized; (b) measuring an optical characteristic of the reaction system; and (c) removing, from the reaction system, an agglutination complex including the subject substance, the specific coupling substance and the magnetic particle by utilizing magnetic force.

대표청구항 ▼

What is claimed is: 1. A specific coupling reaction measuring method for measuring a plurality of subject substances in a sample, comprising the steps of: (a) constructing a reaction system including said sample and a specific coupling substance for specifically coupling with a first subject substance; (b) measuring an optical characteristic of said reaction system; (c) adding, to said reaction system, a magnetic complex including a magnetic particle and a substance capable of coupling with an agglutination complex including said first subject substance and said specific coupling substance; (d) removing, by utilizing magnetic force, said agglutination complex coupled with said magnetic complex from said reaction system; (e) adding, to said reaction system, another specific coupling substance for specifically coupling with another subject substance; and (f) measuring an optical characteristic of said reaction system after the step (e). 2. The specific coupling reaction measuring method of claim 1, wherein said optical characteristic is an intensity of scattered light or a quantity of transmitted light. 3. The specific coupling reaction measuring method of claim 1, wherein each said magnetic particles has a diameter of approximately 0.05 through 2 μm. 4. The specific coupling reaction measuring method of claim 1, wherein a portion of said magnetic particles are included in said agglutination complex and other magnetic particles remain in said reaction system in the step (a), and said other magnetic particles remaining in said reaction system are removed from said reaction system in the step (d). 5. The specific coupling reaction measuring method of claim 1, wherein said reaction system includes 2 through 6 wt % of polyethylene glycol in the step (e). 6. The specific coupling reaction measuring method of claim 1, wherein said another specific coupling substance is composed of an antigen or antibody for specifically coupling with said another subject substance and a nonmagnetic particle on which said antigen or antibody is immobilized. 7. The specific coupling reaction measuring method of claim 6, wherein said magnetic particle has a diameter of approximately 0.05 through 2 μm and said nonmagnetic particle has a diameter of approximately 0.05 through 2 μm. 8. The specific coupling reaction measuring method of claim 1, wherein a combination of said first subject substance and said another subject substance is a combination of human hemoglobin and human albumin.

이 특허에 인용된 특허 (25)

Terstappen Leon W. M. M. (Huntingdon Valley PA) Rao Galla C. (Princeton NJ) Gohel Dhanesh I. (Levittown PA) Feeley Brian P. (Easton PA) Gross Steven (Ambler PA) Church Ellen S. (Trenton NJ) Liberti P, Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population th.
상세보기
Yguerabide, Juan; Yguerabide, Evangelina E.; Kohne, David E.; Jackson, Jeffrey T., Analyte assay using particulate labels.
상세보기
Imai Kyoko (Katsuta JPX) Imai Kazumichi (Katsuta JPX) Nomura Yasushi (Mito JPX), Analytical system useful in diagnosis of the condition of a disease.
상세보기
D. Jed Harrison CA; Richard Oleschuk CA; Loranelle Shultz-Lockyear ; Cameron Skinner CA; Paul Li CA, Apparatus and method for trapping bead based reagents within microfluidic analysis systems.
상세보기
Forrest Gordon C. (Chelmsford GB2) Jay Ronald F. (New Malden GB2) Clements John A. (Wallington GB2), Automatic apparatus and method for the assay of fluid samples.
상세보기
Blackburn Gary ; Creager Stephen E. ; Fraser Scott ; Irvine Bruce D. ; Meade Thomas J. ; O'Connor Stephen D. ; Terbrueggen Robert H. ; Vielmetter Jost G. ; Welch Thomas W., Binding acceleration techniques for the detection of analytes.
상세보기
Cox Daniel E. (Franklin MA) Abril Obsidiana (Cambridge MA) Bauminger Sara (Newton MA) Neri Bruce P. (N. Andover MA) Shinefeld Lisa (Lexington MA), Double capture assay method employing a capillary flow device.
상세보기
Sorin, Takaaki, Immunoassay.
상세보기
Niiyama Yasushi,JPX ; Uchida Hiroyasu,JPX ; Tao Ryuji,JPX, Immunoassay method and analyzer using magnetic particles.
상세보기
Ithakissios ; Dionyssis S., In vitro diagnostic test.
상세보기
Farzad Pourahmadi ; William A. McMillan ; Jesus Ching ; Ronald Chang ; Lee A. Christel ; Gregory T. A. Kovacs ; M. Allen Northrup ; Kurt E. Petersen, Integrated fluid manipulation cartridge.
상세보기
Kausch Albert P. (Stonington CT) Narayanswami Sandya (Irvine CA) Manning Jerry E. (San Clemente CA) Hamkalo Barbara A. (Laguna Beach CA), Isolation of biological materials using magnetic particles.
상세보기
Fujiwara Koichi (Mito JPX) Noda Juichi (Mito JPX) Misutani Hiroko (Tokyo JPX) Mizutani ; deceased Hiromichi (late of Tokyo JPX by Hiroko Mizutani ; legal representative), Laser magnetic immunoassay method and apparatus thereof.
상세보기
Hansen W. Peter (20 E. 35th St. ; Apt. 7G New York NY 10016) Cennerazzo Michael (9 Oak St. Weehauken NJ 07087), Light scatter-based immunoassay without particle self aggregation.
상세보기
Ullman Edwin F. (Atherton CA) Ghazarossian Vartan E. (Palo Alto CA) Kurn Nurith (Palo Alto CA) Weng Litai (Mt. View CA), Magnetic composition for particle separation.
상세보기
Pivarnik Philip ; Cao He ; Letcher Stephen V. ; Rand A. Garth, Magnetic focusing immunosensor for the detection of pathogens.
상세보기
Mehta, Tammy Burd; Kopf-Sill, Anne R.; Parce, J. Wallace; Chow, Andrea W.; Bousse, Luc J.; Knapp, Michael R.; Nikiforov, Theo T.; Gallagher, Steve, Manipulation of microparticles in microfluidic systems.
상세보기
Anderson, N. Leigh, Method and apparatus for protein manipulation.
상세보기
Gert Blankenstein DE, Micro-flow system for particle separation and analysis.
상세보기
Vorpahl John (Livermore CA) Ghazarossian Vartan (Menlo Park CA) Ullman Edwin F. (Atherton CA), Multiparameter particle analysis.
상세보기
Jeng Tzyy-Wen ; McDowell Larry L. ; Pezzaniti Joseph Larry ; Oosta Gary M. ; Shain Eric B., Reagentless analysis of biological samples.
상세보기
Hansen W. Peter (New York NY), Simultaneous multiple assays.
상세보기
Hansen W. Peter (New York NY), Simultaneous multiple assays.
상세보기
Ullman, Edwin F.; Pirio, Marcel; Ericson, Mary C.; Wagner, Daniel B.; Davalian, Dariush, Simultaneous screening of multiple analytes.
상세보기
Uchida, Shinya; Konishi, Aya; Torii, Tsuneyoshi; Nakashima, Kazuhiro, Whole blood immunoassay.
상세보기

IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Specific coupling reaction measuring method 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허에 인용된 특허 (25)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Specific coupling reaction measuring method 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허에 인용된 특허 (25)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트