IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
UP-0442659
(2003-05-21)
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등록번호 |
US-7563282
(2009-07-29)
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발명자
/ 주소 |
- Lambrecht, Greg H.
- Moore, Robert Kevin
- Einhorn, Jacob
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출원인 / 주소 |
- Intrinsic Therapeutics, Inc.
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대리인 / 주소 |
Knobbe, Martens, Olson & Bear, LLP
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인용정보 |
피인용 횟수 :
30 인용 특허 :
276 |
초록
▼
Systems for minimally invasive disc augmentation include an anulus augmentation component and a nucleus augmentation component. Both are suited for minimally invasive deployment. The nucleus augmentation component restores disc height and/or replaces missing nucleus pulposus. The anulus augmentatio
Systems for minimally invasive disc augmentation include an anulus augmentation component and a nucleus augmentation component. Both are suited for minimally invasive deployment. The nucleus augmentation component restores disc height and/or replaces missing nucleus pulposus. The anulus augmentation component shields weakened regions of the anulus fibrosis and/or resists escape of natural nucleus pulposus and/or the nucleus augmentation component. Methods and deployment devices are also disclosed. Method of supporting and augmenting a nucleus pulposus by inserting a flexible biocompatible material into the disc space using an anchoring means are also provided.
대표청구항
▼
What is claimed is: 1. A method of supporting and augmenting a nucleus pulposus of an intervertebral disc in a spine comprising: inserting a flexible one-piece biocompatible nucleus augmentation device into the disc space through and entirely beyond a defect in a posterior portion of an anulus; whe
What is claimed is: 1. A method of supporting and augmenting a nucleus pulposus of an intervertebral disc in a spine comprising: inserting a flexible one-piece biocompatible nucleus augmentation device into the disc space through and entirely beyond a defect in a posterior portion of an anulus; wherein said nucleus augmentation device comprises an anchor, a connection member and a nucleus augmentation material, the nucleus augmentation material being at least partially attached to an anchor; anchoring said nucleus augmentation material to a site within an anterior portion of the anulus or a vertebral body adjacent said anterior portion of the anulus; providing a connection member; wherein the connection member provides stiffness under tension and partially or fully prevents said nucleus augmentation material from migrating farther posterior with respect to the anchor; and wherein the augmentation material comprises a channel or slit that receives the connection member and permits sliding along the connection member. 2. The method of claim 1, wherein one or more additional nucleus augmentation devices or nucleus augmentation materials are inserted into the disc. 3. A method of supporting and augmenting a nucleus pulposus of an intervertebral disc in a spine comprising: inserting a flexible one-piece biocompatible nucleus augmentation device into the disc space through and entirely beyond a defect in a posterior portion of an anulus; wherein said nucleus augmentation device comprises an anchor, a connection member and a nucleus augmentation material, the nucleus augmentation material being at least partially attached to an anchor; anchoring said nucleus augmentation material to a site within an anterior portion of the anulus or a vertebral body adjacent said anterior portion of the anulus; providing a connection member; wherein the connection member provides stiffness under tension and partially or fully prevents said nucleus augmentation material from migrating farther posterior with respect to the anchor; and threading the connection member through the augmentation material. 4. The method of claim 3, wherein the nucleus augmentation material is disc-shaped, cube-like, spheroid, ellipsoid, rhombohedral, cylindrical, or amorphous. 5. The method of claim 3, further comprising supporting at least one portion of an anulus fibrosus of the disc. 6. The method of claim 5, wherein the step of supporting at least one portion of an anulus fibrosus comprises supporting at least one portion of a region selected from the group consisting of one or more of following regions: anterior, anterior medial, anterior lateral, posterior, and lateral portion of the anulus fibrosus. 7. The method of claim 3, wherein the nucleus augmentation material comprises collagen. 8. The method of claim 3, wherein the nucleus augmentation material comprises hydrogel. 9. The method of claim 3, wherein the nucleus augmentation material comprises cellulose. 10. The method of claim 3, wherein the step of providing at least one connection member comprises providing at least one connector selected from the group consisting of: sutures, wires, rigid rods, broad bands, pins, woven tubes and webs. 11. The method of claim 3, wherein one or more additional nucleus augmentation devices or nucleus augmentation materials are inserted into the disc. 12. A method of supporting and augmenting a nucleus pulposus of an intervertebral disc in a spine comprising: installing a first anchor in a site in an anterior portion of an anulus or a vertebral body adjacent said anterior portion of the anulus; coupling at least one connector to said anchor; positioning at least one plug of nucleus augmentation material entirely within the volume of the disc nucleus; coupling said plug with said at least one connector; wherein the connector provides stiffness under tension and partially or fully prevents nucleus augmentation material from migrating further posterior with respect to the anchor; and inserting a barrier into an interior of the disc, entirely within the disc nucleus, and proximal to a defect in an anulus, thereby preventing passage of nucleus augmentation material through said defect. 13. The method of claim 12, further comprising affixing said barrier to said anulus. 14. The method of claim 12, wherein inserting said barrier comprises inserting a barrier with a larger area than an area of said defect. 15. The method of claim 12, wherein inserting said barrier comprises inserting a barrier comprising at least one of woven material, polyamide, polyester, polyethylene, an expanded material, expanded polytetrafluoroethylene, a biologic material, cross-linked collagen, and cellulose. 16. The method of claim 12, wherein inserting said barrier comprises inserting a barrier comprising an expandable component. 17. A method of supporting and augmenting a nucleus pulposus of an intervertebral disc in a spine comprising: installing a first anchor in an anterior portion of the spine within a first endplate; inserting a nucleus augmentation support member entirely within the region occupied by a disc nucleus; coupling a connection member to said anchor, wherein the connection member is stiff under tension and partially or fully prevents the nucleus augmentation material from migrating further posterior with respect to the anchor; coupling said nucleus augmentation support member to said connection member; and wherein coupling said nucleus augmentation support member to said connection member comprises threading the connection member into said nucleus augmentation support member. 18. A method of supporting and augmenting a nucleus pulposus of an intervertebral disc in a spine comprising: installing a first anchor in an anterior portion of the spine within a first endplate; inserting a nucleus augmentation support member entirely within the region occupied by a disc nucleus; coupling a connection member to said anchor; wherein the connection member is stiff under tension and partially or fully prevents the nucleus augmentation material from migrating further posterior with respect to the anchor; coupling said nucleus augmentation support member to said connection member; and wherein coupling said nucleus augmentation support member to said second connection member comprises sliding the connection member into a slit or channel contained in said nucleus augmentation support member.
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